A Retrospective Evaluation of Ototoxicity Monitoring in a Cohort of Pediatric Patients With Solid Tumors, Treated in the Dutch National Cancer Center [PDF]
Cancer ReportsOtotoxicity is an adverse effect of childhood cancer treatment with a negative impact on speech‐language development and quality of life. This study aimed to retrospectively assess ototoxicity monitoring in a national cohort of pediatric patients with ...
Harm Van Tinteren +2 more
exaly +3 more sources
Ototoxicity Associated with Antineoplastic Agents in the Pediatric Population: An Evidence-Based Review of Auditory Monitoring Strategies and Contemporary Diagnostic Frameworks—Narrative Review [PDF]
DiagnosticsOtotoxicity represents a clinically significant complication of anticancer therapy in pediatric patients. Cytotoxic agents used in oncology, particularly platinum-based chemotherapy, may induce damage to the auditory and vestibular systems, resulting in ...
Aleksandra Wojno +4 more
doaj +3 more sources
Ototoxicity monitoring through the eyes of the treating physician: Perspectives from pulmonology and medical oncology [PDF]
International Journal of Audiology, 2018 Objectives: Integrating audiological management into the care pathways of clinical specialties that prescribe ototoxic medications for essential, often life-preserving medical care that is critical for early hearing loss identification and remediation ...
Dawn Konrad-Martin +2 more
exaly +3 more sources
Monitoring Ototoxicity in Cancer Patients Undergoing Platinum-Based Chemotherapy and Radiation in Saudi Arabia: Challenges and Solutions [PDF]
Journal of Multidisciplinary HealthcareArwa AlJasser Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi ArabiaCorrespondence: Arwa AlJasser, Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud ...
AlJasser A
doaj +3 more sources
Ototoxicity monitoring in children treated with platinum chemotherapy [PDF]
International Journal of Audiology, 2018 Objective: To review the prevalence, mechanisms, clinical presentation, risk factors and implications of platinum-induced ototoxicity in paediatric cancer patients based on published evidence, discuss options for monitoring hearing in young children ...
Kristin Knight, Beth Brooks
exaly +4 more sources
The audiogram: Detection of pure-tone stimuli in ototoxicity monitoring and assessments of investigational medicines for the inner ear. [PDF]
J Acoust Soc Am, 2022 Pure-tone thresholds have long served as a gold standard for evaluating hearing sensitivity and documenting hearing changes related to medical treatments, toxic or otherwise hazardous exposures, ear disease, genetic disorders involving the ear, and ...
Le Prell CG, Brewer CC, Campbell KCM.
europepmc +2 more sources
Improving ototoxicity monitoring in patients receiving aminoglycosides using a novel digital approach: a quality improvement project. [PDF]
BMJ Open QualAminoglycoside antibiotics cause ototoxicity for which baseline audiometric testing is recommended but often not done. Barriers to successful implementation include limited availability of sound-booths and audiologists.
Cheong J +17 more
europepmc +2 more sources
Long-Term Variability of Distortion-Product Otoacoustic Emissions in Infants and Children and Its Relation to Pediatric Ototoxicity Monitoring. [PDF]
Ear Hear, 2020 Supplemental Digital Content is available in the text. Objective: Distortion-product otoacoustic emissions (DPOAEs) provide a rapid, noninvasive measure of outer hair cell damage associated with chemotherapy and are a key component of pediatric ...
Konrad-Martin D +5 more
europepmc +2 more sources
Applying U.S. national guidelines for ototoxicity monitoring in adult patients: perspectives on patient populations, service gaps, barriers and solutions. [PDF]
Int J Audiol, 2018 Objectives: To promote establishment of effective ototoxicity monitoring programs (OMPs), this report reviews the U.S. national audiology guidelines in relation to “real world” OMP application. Background is provided on the mechanisms, risks and clinical
Konrad-Martin D +6 more
europepmc +2 more sources
BMC Health Services Research, 2022 Background Ototoxicity monitoring is uncommon in South Africa, despite the increased use of ototoxic medication to manage the burden of disease in the country.
Jessica Paken +3 more
doaj +2 more sources