Results 11 to 20 of about 4,345 (137)

Mechanisms, prevention, and management of aminoglycoside-induced hearing loss in neonates and children: a translational review [PDF]

Frontiers in Pharmacology
ObjectiveAminoglycoside antibiotics remain essential for treating serious neonatal and pediatric infections, yet carry a well-documented risk of permanent auditory and vestibular toxicity.
Sílvia M. Illamola, Catherine M. Sherwin, Catherine M. Sherwin, Catherine M. Sherwin, Catherine M. Sherwin, Lauren C. Ferguson, Angela K. Birnbaum, Angela K. Birnbaum, Angela K. Birnbaum, Ravindhra G. Elluru, Janelle D. Vaughns, Janelle D. Vaughns   +11 more
doaj   +2 more sources

Monitoring Ototoxicity in Cancer Patients Undergoing Platinum-Based Chemotherapy and Radiation in Saudi Arabia: Challenges and Solutions [PDF]

Journal of Multidisciplinary Healthcare
Arwa AlJasser Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi ArabiaCorrespondence: Arwa AlJasser, Department of Rehabilitation Sciences, College of Applied Medical Sciences, King Saud ...
AlJasser A
doaj   +2 more sources

Mobile Audiometry for Use in Ototoxicity Monitoring Programs: A Scoping Review. [PDF]

J Audiol Otol
Ototoxicity monitoring programs (OMPs) for cisplatin-induced hearing loss have not been widely adopted in clinical practice for various reasons. Mobile audiometry (MA) offers cost and convenience advantages over conventional pure-tone audiometry (CA) and it is currently used in hearing screening. However, there is no consensus on whether MA can replace
Yim PWC, Lim ZH.
europepmc   +3 more sources

Improving ototoxicity monitoring in patients receiving aminoglycosides using a novel digital approach: a quality improvement project [PDF]

BMJ Open Quality
Aminoglycoside antibiotics cause ototoxicity for which baseline audiometric testing is recommended but often not done. Barriers to successful implementation include limited availability of sound-booths and audiologists.
Andrew Jones, Francis Drobniewski, Michael Loebinger, Emily Frost, Julie Wilkins, Presanna Premachandra, Anand Shah, Su Madge, Nicholas J Simmonds, Ricardo J José, Jamie Cheong, Shereen Boreland, Elaine Shattock, Elaine Bowman, Barbara Belkarty, Imogen Felton, Emem-Fong Ukor, Janet Stowell   +17 more
doaj   +2 more sources

Exploring and Overcoming Challenges for Efficient Audiological Testing in Children Under 5 Years of Age—Screening with Otoacoustic Emissions [PDF]

Audiology Research
Background/Objectives: Cisplatin-exposed pediatric cancer patients are at increased risk of ototoxicity, particularly those under 5 years of age. In this group, audiological monitoring is challenging, as interpretation of otoacoustic emissions (OAEs) and
Nienke Streefkerk, Franciscus A. Diepstraten, Evangeline A. Huis in ’t Veld, Antoinette am Zehnhoff-Dinnesen, Martine van Grotel, Katrin Neumann, Annelot J. M. Meijer, Frédéric Amant, Ross Parfitt, L’udmila Verešpejová, Penelope R. Brock, Lisa L. Hunter, Hiske W. Helleman, Beth Brooks, Kaukab M. Rajput, Kristin Knight, Marry M. van den Heuvel-Eibrink, Alexander E. Hoetink   +17 more
doaj   +2 more sources

Audiologic Assessment and Management of Teprotumumab-Associated Ototoxicity: An Updated Narrative Review [PDF]

Audiology Research
Introduction: Teprotumumab (Tepezza®), an insulin-like growth factor-1 receptor (IGF-1R) antagonist, is the first FDA-approved targeted therapy for thyroid eye disease (TED).
John Williams, Alex Elkins, Alp Sarigul, Mary Frances Johnson, Charles E. Bishop   +4 more
doaj   +2 more sources

Community-Based Ototoxicity Monitoring for Drug-Resistant Tuberculosis in South Africa: An Evaluation Study [PDF]

International Journal of Environmental Research and Public Health, 2021
Lucia Jane Stevenson, Leigh Biagio-De Jäger, Marien Alet Graham   +2 more
exaly   +2 more sources

Platinum-Induced Ototoxicity in Pediatric Cancer Patients: A Comprehensive Approach to Monitoring Strategies, Management Interventions, and Future Directions [PDF]

Children
Platinum-induced ototoxicity constitutes a significant adverse effect in pediatric oncology, frequently resulting in permanent hearing impairment with profound implications for quality of life, language acquisition, and scholastic performance.
Antonio Ruggiero, Alberto Romano, Palma Maurizi, Dario Talloa, Fernando Fuccillo, Stefano Mastrangelo, Giorgio Attinà   +6 more
doaj   +2 more sources

Clinical Considerations of Amikacin Pharmacotherapy in Adults—A Narrative Review with Focus on Safety and TDM [PDF]

Antibiotics
Background: Amikacin remains a key agent in the treatment of severe and complicated infections due to its bactericidal activity and low risk of Clostridioides difficile infection. It retains activity against most aerobic Gram-negative bacteria, including
Daniel Orzechowski, Aleksandra Mroczkowska, Adrian Bryła, Anna Rapacz   +3 more
doaj   +2 more sources

Evoked otoacoustic emissions — an approach for monitoring cisplatin induced ototoxicity in children

International Journal of Pediatric Otorhinolaryngology, 2001
Cisplatin chemotherapy is associated with an increased risk of ototoxic changes. The incidence of hearing loss after the 1st cisplatin-infusion session is only scarcely mentioned in the international literature. With increasing survival rates, prevention and/or early detection of ototoxicity are important for providing management options.
P Stavroulaki
exaly   +4 more sources