Results 21 to 30 of about 8,213 (210)
Aim: The study explored the South African healthcare context for ototoxicity assessment and management from the audiologists’ perspectives. Materials and Methods: This was done through a survey research methodology that adopted a cross-sectional research
Katijah Khoza-Shangase, Nothando Masondo
doaj +1 more source
Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity [PDF]
Cisplatin-induced ototoxicity is one of the major factors limiting cisplatin chemotherapy. Ototoxicity results from damage to outer hair cells (OHCs) and other regions of the cochlea.
Bhatta, Puspanjali +12 more
core +2 more sources
Ototoxicity: A review of South African studies
Background: Ototoxicity is damage to cells in the inner ear after administering a toxic drug, with a resultant hearing loss. Drugs used to treat illnesses such as cancer, tuberculosis, human immuno-deficiency virus (HIV) and infections are potentially ...
Selvarani Moodley +2 more
doaj +1 more source
Ototoxicity monitoring in children treated with platinum chemotherapy [PDF]
To review the prevalence, mechanisms, clinical presentation, risk factors and implications of platinum-induced ototoxicity in paediatric cancer patients based on published evidence, discuss options for monitoring hearing in young children during treatment and review long-term follow-up guidelines.Narrative literature review.Children treated with ...
Beth, Brooks, Kristin, Knight
openaire +2 more sources
Background: Ototoxicity monitoring during treatment of medical conditions, where the medications used are known to be toxic to the ear, is an important scope of practice of the audiologist; and, is an important clinical service aimed at enhancing ...
Katijah Khoza-Shangase, Megan Stirk
doaj +1 more source
Auditory monitoring in ototoxicity
Some pharmaceutical products are capable of damaging the human auditory system. Technological progress has provided numerous resources to monitor hearing but there still is some controversy regarding the selection of the most sensitive and specific tests.to analyze audiological procedures used in the auditory monitoring of individuals exposed to ...
Jacob, Lilian Cassia Bornia +4 more
openaire +2 more sources
Prevention of cisplatin-induced hearing loss in children: Informing the design of future clinical trials. [PDF]
Cisplatin is an essential chemotherapeutic agent in the treatment of many pediatric cancers. Unfortunately, cisplatin-induced hearing loss (CIHL) is a common, clinically significant side effect with life-long ramifications, particularly for young ...
Chang, Kay +9 more
core +1 more source
Audiological Monitoring of Patients Receiving Ototoxic Drugs [PDF]
Over 200 medications commonly prescribed for the treatment of cancers and some infections can cause inner ear damage, or ototoxicity (ASHA, 2004). Ototoxicity can result in auditory and/or vestibular dysfunction, and the effects can be temporary, but are often permanent.
Dawn Konrad-Martin +5 more
openaire +1 more source
Cisplatin-induced ototoxicity: effects, mechanisms and protection strategies [PDF]
Cisplatin is a highly effective chemotherapeutic agent that is widely used to treat solid organ malignancies. However, serious side effects have been associated with its use, such as bilateral, progressive, irreversible, dose-dependent neurosensory ...
Callejo Castillo, Àngela +3 more
core +1 more source
Adverse Effects and Choice between the Injectable Agents Amikacin and Capreomycin in Multidrug-Resistant Tuberculosis [PDF]
Background: The prolonged use of injectable agents in an MDR-TB regimen is recommended by the WHO despite association with ototoxicity and nephrotoxicity.Objective: We undertook this study to look at the relative adverse effects of capreomycin and ...
Ahuja +42 more
core +1 more source

