Results 21 to 30 of about 4,446,831 (170)

Mechanisms, prevention, and management of aminoglycoside-induced hearing loss in neonates and children: a translational review [PDF]

Frontiers in Pharmacology
ObjectiveAminoglycoside antibiotics remain essential for treating serious neonatal and pediatric infections, yet carry a well-documented risk of permanent auditory and vestibular toxicity.
Sílvia M. Illamola, Catherine M. Sherwin, Catherine M. Sherwin, Catherine M. Sherwin, Catherine M. Sherwin, Lauren C. Ferguson, Angela K. Birnbaum, Angela K. Birnbaum, Angela K. Birnbaum, Ravindhra G. Elluru, Janelle D. Vaughns, Janelle D. Vaughns   +11 more
doaj   +2 more sources

Audiological testing for ototoxicity monitoring in adults with tuberculosis in state hospitals in Gauteng, South Africa

Southern African Journal of Infectious Diseases, 2016
Background: Ototoxicity monitoring during treatment of medical conditions, where the medications used are known to be toxic to the ear, is an important scope of practice of the audiologist; and, is an important clinical service aimed at enhancing ...
Katijah Khoza-Shangase, Megan Stirk
doaj   +2 more sources

Monitoring neonates for ototoxicity [PDF]

International Journal of Audiology, 2017
Objectives: Neonates admitted to the neonatal intensive care unit (NICU) are at greater risk of permanent hearing loss compared to infants in well mother and baby units. Several factors have been associated with this increased prevalence of hearing loss,
A. Garinis, Alison J. Kemph, A. M. Tharpe, J. Weitkamp, C. McEvoy, P. Steyger   +5 more
semanticscholar   +3 more sources

Research protocol: Cisplatin-associated ototoxicity amongst patients receiving cancer chemotherapy and the feasibility of an audiological monitoring program

BMC Women's Health, 2017
Background Cisplatin is an anti-cancer chemotherapy drug classified as an alkylating agent. It is used for the treatment of a variety of cancers such as cervical, breast, stomach, prostate, bladder and oesophageal, to name a few.
J. Paken, C. D. Govender, V. Sewram
doaj   +2 more sources

Exploring and Overcoming Challenges for Efficient Audiological Testing in Children Under 5 Years of Age—Screening with Otoacoustic Emissions [PDF]

Audiology Research
Background/Objectives: Cisplatin-exposed pediatric cancer patients are at increased risk of ototoxicity, particularly those under 5 years of age. In this group, audiological monitoring is challenging, as interpretation of otoacoustic emissions (OAEs) and
Nienke Streefkerk, Franciscus A. Diepstraten, Evangeline A. Huis in ’t Veld, Antoinette am Zehnhoff-Dinnesen, Martine van Grotel, Katrin Neumann, Annelot J. M. Meijer, Frédéric Amant, Ross Parfitt, L’udmila Verešpejová, Penelope R. Brock, Lisa L. Hunter, Hiske W. Helleman, Beth Brooks, Kaukab M. Rajput, Kristin Knight, Marry M. van den Heuvel-Eibrink, Alexander E. Hoetink   +17 more
doaj   +2 more sources

Audiologic Assessment and Management of Teprotumumab-Associated Ototoxicity: An Updated Narrative Review [PDF]

Audiology Research
Introduction: Teprotumumab (Tepezza®), an insulin-like growth factor-1 receptor (IGF-1R) antagonist, is the first FDA-approved targeted therapy for thyroid eye disease (TED).
John Williams, Alex Elkins, Alp Sarigul, Mary Frances Johnson, Charles E. Bishop   +4 more
doaj   +2 more sources

Clinical Considerations of Amikacin Pharmacotherapy in Adults—A Narrative Review with Focus on Safety and TDM [PDF]

Antibiotics
Background: Amikacin remains a key agent in the treatment of severe and complicated infections due to its bactericidal activity and low risk of Clostridioides difficile infection. It retains activity against most aerobic Gram-negative bacteria, including
Daniel Orzechowski, Aleksandra Mroczkowska, Adrian Bryła, Anna Rapacz   +3 more
doaj   +2 more sources

Audiological ototoxicity monitoring guidelines: a review of current evidence and appraisal of quality using the AGREE II tool

International Journal of Audiology, 2023
Objective The effectiveness of audiological monitoring for detecting early hearing changes in patients receiving ototoxic medication could be limited by the lack of adequate audiological ototoxicity monitoring (OtoM) guidelines.
Georgia M Lester, Wayne J. Wilson, Barbra H. B. Timmer, R. Ladwa   +3 more
semanticscholar   +1 more source

Mobile Audiometry for Use in Ototoxicity Monitoring Programs: A Scoping Review. [PDF]

J Audiol Otol
Ototoxicity monitoring programs (OMPs) for cisplatin-induced hearing loss have not been widely adopted in clinical practice for various reasons. Mobile audiometry (MA) offers cost and convenience advantages over conventional pure-tone audiometry (CA) and it is currently used in hearing screening. However, there is no consensus on whether MA can replace
Yim PWC, Lim ZH.
europepmc   +3 more sources

Proposed comprehensive ototoxicity monitoring program for VA healthcare (COMP-VA). [PDF]

J Rehabil Res Dev, 2014
Konrad-Martin D, Reavis KM, McMillan G, Helt WJ, Dille M.   +4 more
europepmc   +2 more sources