Results 31 to 40 of about 8,213 (210)

Cisplatin-associated ototoxicity: perspectives from a single institution cervical cancer cohort and implications for developing a locally responsive monitoring programme in a public healthcare setting

open access: yesBMC Health Services Research, 2022
Background Ototoxicity monitoring is uncommon in South Africa, despite the increased use of ototoxic medication to manage the burden of disease in the country.
Jessica Paken   +3 more
doaj   +1 more source

The Ototoxicity of Antimalarial Drugs—A State of the Art Review

open access: yesFrontiers in Neurology, 2021
This review summarizes current knowledge about the occurrence of hearing and balance disorders after antimalarial drugs treatment. It also examines the clinical applications of antimalarials, their mechanisms behind this ototoxicity and how it can be ...
Magdalena Jozefowicz-Korczynska   +2 more
doaj   +1 more source

Clinical Issues Surrounding Once-Daily Aminoglycoside Dosing in Children [PDF]

open access: yes, 2003
Aminoglycoside antibiotics are first-line treatment for many infectious diseases in the pediatric population and are effective in adults. The traditional dosing interval in children is every 8–12 hours.
Buss, William F.   +2 more
core   +2 more sources

Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes. [PDF]

open access: yes, 2015
Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats (P2) and adult Balb/C mice.
Choe, Seong-Kyu   +11 more
core   +2 more sources

Gentamicin Exposure and Sensorineural Hearing Loss in Preterm Infants. [PDF]

open access: yes, 2016
To evaluate the impact of gentamicin exposure on sensorineural hearing loss (SNHL) in very low birth weight (VLBW) infants. Exposure to gentamicin was determined in infants born between 1993 and 2010 at a gestational age < 32 weeks and/or with a ...
Bickle Graz, M.   +6 more
core   +2 more sources

Antibiotic Adverse Reactions and Drug Interactions [PDF]

open access: yes, 2008
Magnetic force microscopy (MFM) offers a unique insight into the nanoscopic scale domain structures of magnetic materials. However, MFM is generally regarded as a qualitative technique and, therefore, requires meticulous calibration of the magnetic ...
Dr.yekefallah, leili
core   +4 more sources

Medical management of Pseudomonas aeruginosa endocarditis: A case report

open access: yesJournal of Microbiology and Infectious Diseases, 2023
Background: Pseudomonas aeruginosa is a rare cause of infective endocarditis. There is no standard treatment regimen for the management of infective endocarditis caused by this organism. Pseudomonas aeruginosa produces biofilm on the endocardial surface
Sameer Abdul Samad   +5 more
doaj   +1 more source

Practices employed by audiologists in the management of adult patients with multidrug-resistant tuberculosis in South Africa

open access: yesSouth African Family Practice, 2015
Introduction: Aminoglycosides used for treating multidrug-resistant (MDR) tuberculosis are ototoxic, leading to a need for audiological monitoring. While audiologists monitor ototoxicity, currently there are no guidelines on monitoring in the South ...
M. Govender, J. Paken
doaj   +1 more source

Distortion-Product Otoacoustic Emission Test Performance for Ototoxicity Monitoring [PDF]

open access: yesEar & Hearing, 2011
A nonbehavioral method for monitoring ototoxicity in patients treated with cisplatin is needed because patients enduring chemotherapy may not be well or cooperative enough to undergo repeated hearing tests. Distortion-product otoacoustic emissions (DPOAEs) provide a nonbehavioral measure of auditory function that is sensitive to cisplatin exposure ...
Kelly M, Reavis   +7 more
openaire   +2 more sources

Vancomycin toxicity in neonates: a review of the evidence. [PDF]

open access: yes, 2016
PURPOSE OF REVIEW: Vancomycin is a first-line agent in the treatment of serious Gram-positive infections in the neonatal population. The published evidence on vancomycin toxicity in neonates is limited.
Heath, PT   +3 more
core   +1 more source

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