Establishing a pharmacotherapy induced ototoxicity programme within a service-learning approach
South African Journal of Communication Disorders, 2015 Pharmacotherapy-induced ototoxicity is growing, especially in developing countries such as South Africa. This highlights the importance of ototoxicity monitoring and management of hearing loss.
Natalie Schellack +4 more
doaj +1 more source
Otoacoustic emissions: An approach for monitoring aminoglycoside‐induced ototoxicity [PDF]
The Laryngoscope, 1994 AbstractOtotoxic drugs, such as aminoglycosides, affect outer hair cell integrity in the inner ear. Transiently evoked otoacoustic emission (TEOAE) characteristics are related to outer hair cell function and can be expected to reflect the influence of ototoxic agents.
M A, Hotz, F P, Harris, R, Probst
openaire +2 more sources
Linear cyclodextrin polymer prodrugs as novel yherapeutics for Niemann-Pick type C1 disorder [PDF]
, 2018 Niemann-Pick Type C1 disorder (NPC) is a rare lysosomal storage disease characterized by the accumulation of cholesterol in lysosomes. NPC has no FDA approved treatments yet, however 2-hydroxypropyl-β-cyclodextrin (HPβCD) has shown efficacy for treating ...
Aditya Kulkarni +8 more
core +1 more source
BMC Women's Health, 2021 Background Cisplatin is a popular antineoplastic agent used to treat cervical cancer in women from low and middle-income countries. Cisplatin treatment is associated with ototoxicity, often resulting in hearing loss.
Jessica Paken +4 more
doaj +1 more source
Evaluation of Audiometric Threshold Shift Criteria for Ototoxicity Monitoring [PDF]
Journal of the American Academy of Audiology, 2010 Background:There is disagreement about ototoxicity monitoring methods. Controversy exists about what audiometric threshold shift criteria should be used, which frequencies should be tested, and with what step size. An evaluation of the test performance achieved using various criteria and methods for ototoxicity monitoring may help resolve these issues.
Dawn, Konrad-Martin +6 more
openaire +2 more sources
Amikacin use and therapeutic drug monitoring in adults : do dose regimens and drug exposures affect either outcome or adverse events? A systematic review [PDF]
, 2016 Objectives To identify the amikacin dosage regimens and drug concentrations consistent with good outcomes and to determine the drug exposures related to nephrotoxicity and ototoxicity.
Brown, Nicholas M. +7 more
core +1 more source
Cisplatin liposome and 6-amino nicotinamide combination to overcome drug resistance in ovarian cancer cells [PDF]
, 2018 Ovarian cancer is an aggressive and lethal cancer usually treated by cytoreductive surgery followed by chemotherapy. Unfortunately, after an initial response, many patients relapse owing mainly to the development of resistance against the standard ...
Catanzaro, Daniela +7 more
core +1 more source
BMC Women's Health, 2017 Background Cisplatin is an anti-cancer chemotherapy drug classified as an alkylating agent. It is used for the treatment of a variety of cancers such as cervical, breast, stomach, prostate, bladder and oesophageal, to name a few.
J. Paken, C. D. Govender, V. Sewram
doaj +1 more source
What do I need to know about aminoglycoside antibiotics? [PDF]
, 2017 The aminoglycosides are broad-spectrum, bactericidal antibiotics that are commonly prescribed for children, primarily for infections caused by Gram-negative pathogens.
Barker, CI, Germovsek, E, Sharland, M
core +1 more source
Ototoxicity in cancer survivors: Experience and proposal of a surveillance protocol
Anales de Pediatría (English Edition), 2021 Introduction: Ototoxicity occurs in different percentages in patients after treatment with platinum-based chemotherapy or cranial radiation therapy. The aim of this study was to present our experience in ototoxicity monitoring.
Mario Sánchez-Canteli +6 more
doaj +1 more source