Results 51 to 60 of about 506,839 (244)

Characterisation of out-of-field dose at shallow depths for external beam radiotherapy: implications for eye lens dose

Australasian Physical & Engineering Sciences in Medicine, 2019
Re-evaluation of the eye lens radio-sensitivity by the ICRP in 2011 resulted in a significant reduction of the threshold for lens opacities from 8 Gy to 0.5 Gy. This has led to an increase in concern for eye lens doses from treatment sites further from the eye than previously considered.
Baradaran, TC, Cutajar, DL, Qi, Y, Ralston, A   +3 more
openaire   +3 more sources

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Characteristic of Tumor Regrowth After Gamma Knife Radiosurgery and Outcomes of Repeat Gamma Knife Radiosurgery in Nonfunctioning Pituitary Adenomas

Frontiers in Oncology, 2021
ObjectiveThis study aimed to report the characteristic of tumor regrowth after gamma knife radiosurgery (GKRS) and outcomes of repeat GKRS in nonfunctioning pituitary adenomas (NFPAs).Design and MethodsThis retrospective study consisted of 369 NFPA ...
Yanli Li, Lisha Wu, Tingting Quan, Junyi Fu, Linhui Cao, Xi Li, Shunyao Liang, Minyi Huang, Yinhui Deng, Jinxiu Yu   +9 more
doaj   +1 more source

Neutron and photon out-of-field doses at cardiac implantable electronic device (CIED) depths

Applied Radiation and Isotopes, 2021
The accuracy of an out-of-field dose from an Elekta Synergy accelerator calculated using the X-ray Voxel Monte Carlo (XVMC) dose algorithm in the Monaco treatment planning system (TPS) for both low-energy (6 MV) and high-energy (15 MV) photons at cardiac implantable electronic device (CIED) depths was investigated through a comparison between MCNPX ...
Hossein Aslian, Mara Severgnini, Navid Khaledi, Stefano Ren Kaiser, Anna Delana, Rossella Vidimari, Mario de Denaro, Francesco Longo   +7 more
openaire   +3 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

The Impact of Temporal Changes in Irradiated nMAG Polymer Gels on Their Applicability in Small Field Dosimetry in Radiotherapy

Gels, 2022
As advanced radiotherapy techniques progress to deliver a high absorbed dose to the target volume while minimizing the dose to normal tissues using intensity-modulated beams, arcs or stereotactic radiosurgery, new challenges occur to assure that the high
Aurimas Krauleidis, Diana Adliene, Zivile Rutkuniene   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

New approach to evaluate the exit dose quality for high radioprotection and radiotherapy efficiency [PDF]

Ядерна фізика та енергетика, 2018
For safety and radioprotection reasons in radiotherapy treatment, the exit dose is evaluated with irradiation field size and photon beam energy. The objective of this study is to introduce an empirical law for predicting the delivered dose at the other ...
Mohamed Bencheikh, Abdelmajid Maghnouj, Jaouad Tajmouati, Abdessamad Didi, Abdesslam Lamrabet, Yassine Benkhouya   +5 more
doaj   +1 more source

Commissioning and out-of-field dose characterisation of the Elekta Unity MRL

, 2022
Marcus Powers commissioned the Southern Hemisphere's first clinical MRI-guided Linear Accelerator and assessed radiation doses during treatments with the machine. He found it was suitable for the provision of cancer therapy and revealed potential unintended radiation deposition to distal patient regions.
openaire   +2 more sources

Out‐of‐field doses and neutron dose equivalents for electron beams from modern Varian and Elekta linear accelerators [PDF]

Journal of Applied Clinical Medical Physics, 2016
Out‐of‐field doses from radiotherapy can cause harmful side effects or eventually lead to secondary cancers. Scattered doses outside the applicator field, neutron source strength values, and neutron dose equivalents have not been broadly investigated for high‐energy electron beams.
Cardenas, Carlos E., Nitsch, Paige L., Kudchadker, Rajat J., Howell, Rebecca M., Kry, Stephen F.   +4 more
openaire   +2 more sources