Results 81 to 90 of about 3,725,551 (310)
Patient Related Outcome Measures, 2018 William E Strauss,1 Michael Auerbach2 1AMAG Pharmaceuticals, Inc., Waltham, MA, USA; 2Auerbach Hematology and Oncology, Baltimore, MD, USA Abstract: Most physicians appear to be aware of the health consequences of advanced anemia, especially in the acute
Strauss WE, Auerbach M
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Patient Related Outcome Measures, 2020 Avery A Rizio,1 Lynne E Broderick,1 Michelle K White,1 Tiffany P Quock2 1Optum Life Sciences, Patient Insights, Johnston, RI, USA; 2Prothena Biosciences Inc, South San Francisco, CA, USACorrespondence: Avery A RizioOptum Life Sciences, Patient Insights ...
Rizio AA +3 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Patient considerations in the management of gout and role of combination treatment with lesinurad
Patient Related Outcome Measures, 2018 Liza W Claus, Joseph J Saseen Department of Clinical Pharmacy, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO, USA Abstract: Gouty arthritis is one of the most common rheumatic diseases, and the prevalence ...
Claus LW, Saseen JJ
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The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Measuring medicine-related experiences from the patient perspective: a systematic review
Patient Related Outcome Measures, 2016 Barbra Katusiime,1 Sarah Corlett,1 Joanne Reeve,2 Janet Krska1 1Medway School of Pharmacy, The Universities of Kent and Greenwich, Chatham, Maritime, Kent, UK; 2Warwick Medical School, University of Warwick, Coventry, UK Background: There is an ...
Katusiime B, Corlett S, Reeve J, Krska J
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Health Outcomes in Pathways to Housing Clients [PDF]
, 2020 Introduction: Homelessness is widespread throughout the United States, with homeless individuals accounting for over half a million of the country’s population.
Alfonso, Kimberly, Weinstein, MD, Lara
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Patient Related Outcome MeasuresDusica Hadzi Boskovic,1 Jayne Smith-Palmer,2 Johannes Pöhlmann,2 Richard F Pollock,2 Steve Hwang,1 David Bruhn1 1Global Value and Real World Evidence, Otsuka Pharmaceutical Development & Commercialization Inc, Princeton, NJ, USA; 2Covalence Research Ltd,
Hadzi Boskovic D +5 more
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