Results 91 to 100 of about 882,725 (292)

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Discovery of new biosynthetic pathways: the lipid A story

Journal of Lipid Research, 2009
The outer monolayer of the outer membrane of Gram-negative bacteria consists of the lipid A component of lipopolysaccharide (LPS), a glucosamine-based saccharolipid that is assembled on the inner surface of the inner membrane.
Christian R.H. Raetz, Ziqiang Guan, Brian O. Ingram, David A. Six, Feng Song, Xiaoyuan Wang, Jinshi Zhao   +6 more
doaj   +1 more source

Phosphorylation of chloroplast ribulose bisphosphate carboxylase/oxygenase small subunit by an envelope-bound protein kinase in situ [PDF]

, 1983
A new protein kinase of the cAMP independent type was found to be bound to the outer envelope membrane of spinach chloroplasts. While stimulated by Mg2+ and inhibited by ADP, the enzyme showed no response to conventional protein substrates and was ...
Buchanan, Bob B., Soll, Jürgen
core  

The mitochondrial receptor complex [PDF]

, 1993
The receptor complex in the mitochondrial outer membrane, which consists of at least seven different proteins, is responsible for the recognition and translocation of cytosolically synthesized preproteins.
Alberts, Baker, Baker, Becker, Bressan, Chen, Fujiki, Hanahan, Harlow, Hartl, Hartl, Hase, Hines, Hines, Innis, Keegstra, Kiebler, Kyshe-Andersen, Kyte, Lill, Mage, Maina, Melton, Moczko, Neupert, Pelham, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Rapoport, Rassow, Rigby, Roise, Saiki, Sambrook, Sanders, Sanger, Schleyer, Schneider, Schneider, Steger, Söllner, Söllner, Söllner, Söllner, Tabor, Vestweber, von Heijne, Wickner, Wickner, Young, Zimmermann   +55 more
core   +4 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Import pathways of precursor proteins into mitochondria [PDF]

, 1988
The precursor of porin, a mitochondrial outer membrane protein, competes for the import of precursors destined for the three other mitochondrial compartments, including the Fe/S protein of the bc1- complex (intermembrane space), the ADP/ATP carrier ...
Neupert, Walter, Pfaller, Rupert, Pfanner, Nikolaus, Rassow, Joachim, Steger, Heinrich F.   +4 more
core  

Characterization of the protein import apparatus in isolated outer envelopes of chloroplasts [PDF]

, 1991
Isolated outer envelope membrane from pea (Pisum sativum L.) chloroplasts can be used in vitro to study binding and partial translocation of precursor proteins destined for the inside of the organelle.
Ansorge, Arnon, Baker, Bonner, Cline, Cornwall, Douce, Flügge, Flügge, Harlow, Hartl, Hartl, Heijne, Hinz, Joyard, Kaderbhai, Kang, Keegstra, Keegstra, Kiebler, Laemmli, Lowry, Lubben, Marshall, Neumann, Olsen, Pain, Pfanner, Robinson, Salomon, Scherer, Schindler, Schnell, Theg, Towbin, Waegemann, Wiedmann   +36 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Outer membrane protein assembly mediated by BAM-SurA complexes

Nature Communications
The outer membrane is a formidable barrier that protects Gram-negative bacteria against environmental threats. Its integrity requires the correct folding and insertion of outer membrane proteins (OMPs) by the membrane-embedded β-barrel assembly machinery
Katherine L. Fenn, Jim E. Horne, Joel A. Crossley, Nils Böhringer, Romany J. Horne, Till F. Schäberle, Antonio N. Calabrese, Sheena E. Radford, Neil A. Ranson   +8 more
doaj   +1 more source

A novel mechanism for the biogenesis of outer membrane vesicles in Gram-negative bacteria

Nature Communications, 2016
Bacteria release outer membrane vesicles (OMVs) that play important roles in pathogenesis and intercellular interactions. Here, Roier et al. provide evidence supporting that phospholipid accumulation in the outer leaflet of the outer membrane ...
Sandro Roier, Franz G. Zingl, Fatih Cakar, Sanel Durakovic, Paul Kohl, Thomas O. Eichmann, Lisa Klug, Bernhard Gadermaier, Katharina Weinzerl, Ruth Prassl, Achim Lass, Günther Daum, Joachim Reidl, Mario F. Feldman, Stefan Schild   +14 more
doaj   +1 more source