Results 91 to 100 of about 586,788 (291)

Polymyxins slow down lateral diffusion of proteins and lipopolysaccharide in the E. coli outer membrane

Communications Biology
Polymyxins are often administered as last resort antibiotics for Gram-negative bacterial infections. However, given unwanted side-effects, efficacy and recent reports of resistance against polymyxins, there is an urgency to develop alternatives.
Dheeraj Prakaash, Syma Khalid
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Comparative studies of Yersinia pestis outer membrane isolation techniques and their potential use in plague epidemiology Estudo comparativo de técnicas de isolamento de membrana externa de Yersinia pestis e seu uso na epidemiologia da peste

Revista do Instituto de Medicina Tropical de São Paulo, 1990
In the present study three techniques for obtaining outer membrane enriched fractions from Yersinia pestis were evaluated. The techniques analysed were: differential solubilization of the cytoplasmic membrane with Sarkosyl or Triton X-100, and ...
Frederico Guilherme Coutinho Abath, Luís Carlos de Sousa Ferreira   +1 more
doaj   +1 more source

Bacterial porin disrupts mitochondrial membrane potential and sensitizes host cells to apoptosis [PDF]

, 2009
The bacterial PorB porin, an ATP-binding beta-barrel protein of pathogenic Neisseria gonorrhoeae, triggers host cell apoptosis by an unknown mechanism. PorB is targeted to and imported by host cell mitochondria, causing the breakdown of the mitochondrial
A Degterev, A Müller, A Müller, AE Deghmane, Anke Harsman, B Shanmugavadivu, Dirk Günther, DM Walther, DR Voelker, E Gottlieb, E Gottlieb, Elke A. Dian-Lothrop, Eva Hauf, FJ Bauer, FJ Castora, G Kroemer, G Schatz, Hank Steven Seifert, I Guilvout, IE Gentle, Ines Herrmann, J Song, JE Chipuk, JF Weel, Joachim Rassow, K Hill, Katharina Ross, Krishnaraj Rajalingam, L Scorrano, LA Pon, LC Armstrong, LM Loew, M Meinecke, MC Wei, Michael Meinecke, MP Bos, N Bolender, N Pfanner, N Wiedemann, N Wiedemann, O Kepp, O Kepp, Oliver Kepp, P Massari, P Massari, P Mueller, R Voulhoux, RD Taylor, Richard Wagner, Robert Hurwitz, RP Zahedi, S Desagher, S Kutik, S Makino, SA Paschen, SA Paschen, T Krimmer, T Rudel, Thomas Rudel, V Kozjak, V Kozjak-Pavlovic, V Robert, Vera Kozjak-Pavlovic, Volker Brinkmann, W Neupert   +64 more
core   +4 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Functional Versatility of Vibrio cholerae Outer Membrane Proteins

Applied Microbiology
A key feature that differentiates Gram-positive and Gram-negative bacteria is the outer membrane, an asymmetric membrane composed of lipopolysaccharides, phospholipids, lipoproteins and integral proteins, including the outer-membrane proteins (OMPs).
Annabelle Mathieu-Denoncourt, Marylise Duperthuy   +1 more
doaj   +1 more source

PHOSPHORYLATION/DEPHOSPHORYLATION OF MITOCHONDRIAL PROTEINS IN REDOX-SIGNALLING OF HIGHER PLANTS UNDER ABIOTIC STRESS CONDITIONS [PDF]

Journal of Stress Physiology & Biochemistry, 2012
We studied an impact of the widely spread intra-cellular signals Ca2+ and сAMP on activity of the protein phosphorylation in maize mitochondria. The use of the isolated mitochondria is a convenient model system for investigation of the different ...
Subota I.Yu., A.Sh. Arziev, A.I. Katyshev, M.V. Koulintchenko, Yu.M. Konstantinov   +4 more
doaj  

Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosis

eLife, 2019
During apoptosis, Bcl-2 proteins such as Bax and Bak mediate the release of pro-apoptotic proteins from the mitochondria by clustering on the outer mitochondrial membrane and thereby permeabilizing it.
Nicholas R Ader, Patrick C Hoffmann, Iva Ganeva, Alicia C Borgeaud, Chunxin Wang, Richard J Youle, Wanda Kukulski   +6 more
doaj   +1 more source

Membrane proteins in the outer mebrane of plastids and mitochondria [PDF]

, 2006
Channels of the plastid and mitochondrial outer membranes facilitate the turnover of molecules and ions via these membranes. Although channels have been studied many questions pertaining to the whole diversity of plastid and mitochondrial channels in ...
Ilkavets, Iryna
core  

The Borrelia afzelii outer membrane protein BAPKO_0422 binds human Factor-H and is predicted to form a membrane-spanning beta-barrel [PDF]

, 2015
The deep evolutionary history of the Spirochetes places their branch point early in the evolution of the diderms, before the divergence of the present day Proteobacteria.
Adam Dyer, Albrecht, Bagos, Barcena-Uribarri, Behera, Bhide, Bordier, Brooks, Bunikis, Cabello, Casjens, Coutte, Crago, Crother, Cullen, Di, Dietrich, Eddy, Eswar, Fairman, Feng, Finn, Fraser, Freeman, Gemma Brown, Gessmann, Greene, Guina, Heffernan, Hong, Jaroszewski, Kenedy, Koebnik, Kopp, Kraiczy, Kurtenbach, Lenhart, Lenka Stejskal, Livengood, Margos, Mertins, Mittal, Nair, Oksi, Ornstein, Ostberg, Paetzel, Pautsch, Petersen, Peter R. Laity, Pettersen, Prasadarao, Preac-Mursic, Pugsley, Pulzova, Richard J. Bingham, Robert, Rogovskyy, Schmidli, Schulz, Setubal, Skare, Sperisen, Steere, Struyve, Sugawara, Svergun, Tamm, Thein, Tilly, Tommassen, Vogt, Volkov, Xie, Yamashita, Yang, Zhang   +76 more
core   +1 more source