Results 11 to 20 of about 284,749 (288)
Outer membrane vesicle vaccines [PDF]
Seminars in Immunology, 2020 Outer Membrane Vesicles (OMV) have received increased attention in recent years as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis serogroup B have been extensively explored. Following the success of the MeNZB OMV vaccine in controlling an outbreak of N.
Francesca, Micoli, Calman A, MacLennan
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Bacterial outer membrane vesicle nanorobot. [PDF]
Proc Natl Acad Sci U S AAutonomous nanorobots represent an advanced tool for precision therapy to improve therapeutic efficacy. However, current nanorobotic designs primarily rely on inorganic materials with compromised biocompatibility and limited biological functions. Here, we introduce enzyme-powered bacterial outer membrane vesicle (OMV) nanorobots. The immobilized urease
Tang S +15 more
europepmc +5 more sources
Outer Membrane Vesicle Vaccine Platforms. [PDF]
BioDrugs, 2023 Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative bacteria during their growth and constitute an important virulence factor for bacteria, helping them to survive through harsh environmental conditions. Native OMVs, naturally-released from bacteria, are produced at a level too low for vaccine manufacturing, requiring ...
Micoli F, Adamo R, Nakakana U.
europepmc +4 more sources
Outer membrane vesicle vaccines for Neisseria gonorrhoeae. [PDF]
Nat Rev Urol, 2022 Multidrug-resistant Neisseria gonorrhoeae is a global health problem, and the development of a vaccine is considered essential for the effective control of gonorrhoea. The use of outer membrane vesicle vaccines to prevent N. gonorrhoeae infection has garnered considerable interest, and a recent study using a mouse model of experimental gonococcal ...
Semchenko EA, Seib KL.
europepmc +6 more sources
Outer Membrane Vesicle-Host Cell Interactions [PDF]
Microbiology Spectrum, 2019 ABSTRACT Outer membrane vesicles (OMVs) are nanosized proteoliposomes derived from the outer membrane of Gram-negative bacteria. They are ubiquitously produced both in culture and during infection and are now recognized to play crucial roles during host-microbe interactions.
Jessica D, Cecil +3 more
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Frontiers in Microbiology, 2021 Outer membrane vesicles (OMVs) produced by Gram-negative bacteria are mediators of cell survival and pathogenesis by facilitating virulence factor dissemination and resistance to antimicrobials.
Shelby L. Reimer +7 more
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Heat shock enhances outer-membrane vesicle release in Bordetella spp.
Current Research in Microbial Sciences, 2021 Pertussis, also known as whooping cough, is caused by the Gram-negative bacterium Bordetella pertussis, an obligate human pathogen. Despite high vaccination rates in high-income countries, resurgence of pertussis cases is an occurring problem that urges ...
Eline F. de Jonge +5 more
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DNA Inversion Regulates Outer Membrane Vesicle Production in Bacteroides fragilis. [PDF]
PLoS ONE, 2016 Phase changes in Bacteroides fragilis, a member of the human colonic microbiota, mediate variations in a vast array of cell surface molecules, such as capsular polysaccharides and outer membrane proteins through DNA inversion.
Haruyuki Nakayama-Imaohji +10 more
doaj +2 more sources
mBio, 2016 The ability of Gram-negative bacteria to carefully modulate outer membrane (OM) composition is essential to their survival. However, the asymmetric and heterogeneous structure of the Gram-negative OM poses unique challenges to the cell’s successful ...
Katherine E. Bonnington, Meta J. Kuehn
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Bacterial outer membrane vesicle biogenesis: a new mechanism and its implications
Microbial Cell, 2016 Outer membrane vesicle (OMV) release by Gram-negative bacteria has been observed and studied for decades. First considered as a by-product of cell lysis, it soon became evident that OMVs are actively secreted from the outer membrane (OM) of Gram-negative
Sandro Roier +3 more
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