Results 31 to 40 of about 131,361 (186)
Background: Gram-negative bacteria actively secrete outer membrane vesicles into the surrounding environment and these vesicles have been shown to play various physiological and protective roles such as carrying antibiotic-degrading enzymes and acting as
Wouter André van der Westhuizen +3 more
doaj +1 more source
Budding and vesiculation induced by conical membrane inclusions [PDF]
Conical inclusions in a lipid bilayer generate an overall spontaneous curvature of the membrane that depends on concentration and geometry of the inclusions. Examples are integral and attached membrane proteins, viruses, and lipid domains.
B. Alberts +5 more
core +2 more sources
Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle-based vaccine platform, for efficient viral antigen delivery. [PDF]
Hu K +13 more
europepmc +2 more sources
Dynamical regimes and hydrodynamic lift of viscous vesicles under shear [PDF]
The dynamics of two-dimensional viscous vesicles in shear flow, with different fluid viscosities $\eta_{\rm in}$ and $\eta_{\rm out}$ inside and outside, respectively, is studied using mesoscale simulation techniques. Besides the well-known tank-treading
Benjamin Schmidt +7 more
core +2 more sources
Knockout of mlaA increases Escherichia coli virulence in a silkworm infection model.
The mlaA gene encodes a lipoprotein to maintain an outer membrane lipid asymmetry in gram-negative bacteria. Although the role of mlaA in bacterial virulence has been studied in several bacterial species, there are no reports of its role in E.
Haruka Nasu +3 more
doaj +2 more sources
Porphyromonas gingivalis Outer Membrane Vesicles Increase Vascular Permeability [PDF]
Periodontitis is increasingly associated with increased risk of cardiovascular and other systemic diseases. The Gram-negative anaerobe, Porphyromonas gingivalis, is a key periodontal pathogen, and several lines of evidence link the presence of this bacterium in the circulation with vascular disease.
Farrugia, C. +2 more
openaire +4 more sources
Microparticle assembly pathways on lipid membranes [PDF]
Understanding interactions between microparticles and lipid membranes is of increasing importance, especially for unraveling the influence of microplastics on our health and environment.
Heinrich, Doris +2 more
core +3 more sources
Microbial biosynthesis of designer outer membrane vesicles [PDF]
Outer membrane vesicles (OMVs) are nanoscale proteoliposomes that are ubiquitously secreted by Gram-negative bacteria. Interest in these bioparticles has escalated over the years, leading to discoveries regarding their composition, production, and vaccine potential.
Jenny L, Baker +4 more
openaire +2 more sources
How Well Can You Tailor the Charge of Lipid Vesicles? [PDF]
Knowledge and control of surface charge or potential is important for tailoring colloidal interactions. In this work, we compare widely used zeta potential (ζ) measurements of charged lipid vesicle surface potential to direct measurements using the ...
Docto, D +6 more
core +2 more sources
Engineering Planar Gram-Negative Outer Membrane Mimics Using Bacterial Outer Membrane Vesicles
AbstractAntibiotic resistance is a major challenge in modern medicine. The unique double membrane structure of gram-negative bacteria limits the efficacy of many existing antibiotics and adds complexity to antibiotic development by limiting transport of antibiotics to the bacterial cytosol. New methods to mimic this barrier would enable high-throughput
Aarshi N. Singh +4 more
openaire +3 more sources

