Results 51 to 60 of about 284,749 (288)
A Bilayer-Couple Model of Bacterial Outer Membrane Vesicle Biogenesis
mBio, 2012 Gram-negative bacteria naturally produce outer membrane vesicles (OMVs) that arise through bulging and pinching off of the outer membrane. OMVs have several biological functions for bacteria, most notably as trafficking vehicles for toxins ...
Jeffrey W. Schertzer, Marvin Whiteley
doaj +1 more source
Bacterial Outer Membrane Vesicles as Antibiotic Delivery Vehicles [PDF]
Frontiers in Immunology, 2021 Bacterial outer membrane vesicles (OMVs) are nanometer-scale, spherical vehicles released by Gram-negative bacteria into their surroundings throughout growth. These OMVs have been demonstrated to play key roles in pathogenesis by delivering certain biomolecules to host cells, including toxins and other virulence factors.
Shannon M. Collins, Angela C. Brown
openaire +3 more sources
Polymorphic Regulation of Outer Membrane Lipid A Composition
mBio, 2016 The importance of the polymorphic-phase behavior of lipid A structural variations in determining their endotoxic activities has been recognized previously, but any potential role for lipid A polymorphism in controlling outer membrane structure and ...
Russell E. Bishop
doaj +1 more source
Stem cell research & therapeutics, 2019 Sepsis remains a source of high mortality in hospitalized patients despite proper antibiotic approaches. Encouragingly, mesenchymal stromal cells (MSCs) and their produced extracellular vesicles (EVs) have been shown to elicit anti-inflammatory effects ...
Kyong-Su Park +8 more
semanticscholar +1 more source
Proteomics of Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles
PLOS ONE, 2015 Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins such as cytolethal distending toxin (CDT) and leukotoxin (LtxA) into human host cells and to act as ...
Kieselbach, Thomas +3 more
openaire +5 more sources
Frontiers in Immunology, 2018 Gram-negative pathogens ubiquitously shed outer membrane vesicles (OMVs) that play a central role in initiating and regulating pathogenesis in the host.
L. Turner +9 more
semanticscholar +1 more source
mSystems, 2021 Outer membrane vesicles (OMVs) are universally produced by prokaryotes and play important roles in symbiotic and pathogenic interactions. They often contain DNA, but a mechanism for its incorporation is lacking. Here, we show that Dinoroseobacter shibae,
Hui Wang +14 more
doaj +1 more source
PLoS Pathogens, 2017 Outer membrane vesicles (OMVs) are important tools in bacterial virulence but their role in the pathogenesis of infections caused by enterohemorrhagic Escherichia coli (EHEC) O157, the leading cause of life-threatening hemolytic uremic syndrome, is ...
M. Bielaszewska +15 more
semanticscholar +1 more source
Pharmaceutics, 2023 Bioinspired (or biologically inspired) drug delivery systems (DDSs) have been intensively studied in the last decades. As bioinspired DDSs, membrane vesicles, including extracellular vesicles (EVs) released from eukaryotic cells, outer membrane vesicles (
Chenhan Sun +5 more
doaj +1 more source
Biopearling of Interconnected Outer Membrane Vesicle Chains by a Marine Flavobacterium
Applied and Environmental Microbiology, 2019 Microorganisms produce membrane vesicles. One synthesis pathway seems to be pearling that describes the physical formation of vesicle chains from phospholipid vesicles via extended tubes. Bacteria with vesicle chains had been observed as well as bacteria
Tanja Fischer +10 more
semanticscholar +1 more source