BACTERIAL OUTER MEMBRANE VESICLES AND VACCINE APPLICATIONS [PDF]
Frontiers in Immunology, 2014 Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of self ...
Reinaldo eAcevedo +10 more
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Evaluation of Helicobacter pylori-derived outer membrane vesicles on the expression of inflammatory cytokines [PDF]
Iranian Journal of MicrobiologyBackground and Objectives: Helicobacter pylori infection has been increasingly linked to extra-gastric diseases. Outer membrane vesicles are a key virulence factor of H. pylori. This study investigates the influence of H.
Maryam Mohammadbeigi +10 more
doaj +2 more sources
Outer Membrane Vesicles: An Emerging Vaccine Platform
Vaccines, 2022 Vaccine adjuvants are substances that improve the immune capacity of a recombinant vaccine to a great extent and have been in use since the early 1900s; they are primarily short-lived and initiate antigen activity, mainly an inflammatory response.
Dharmendra Kashyap +8 more
doaj +3 more sources
Proteomics of Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles. [PDF]
PLoS ONE, 2015 Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins ...
Thomas Kieselbach +3 more
doaj +5 more sources
Acinetobacter baumannii secretes cytotoxic outer membrane protein A via outer membrane vesicles. [PDF]
PLoS ONE, 2011 Acinetobacter baumannii is an important nosocomial pathogen that causes a high morbidity and mortality rate in infected patients, but pathogenic mechanisms of this microorganism regarding the secretion and delivery of virulence factors to host cells have
Jong Sook Jin +6 more
doaj +4 more sources
Outer membrane vesicles: A bacterial-derived vaccination system
Frontiers in Microbiology, 2022 Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
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Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium
BMC Microbiology, 2008 Background Outer membrane vesicles (OMVs) are released from the outer membrane of many Gram-negative bacteria. These extracellular compartments are known to transport compounds involved in cell-cell signalling as well as virulence associated proteins, e ...
Niehaus Karsten +3 more
doaj +2 more sources
Bacterial Outer Membrane Vesicles as Antibiotic Delivery Vehicles [PDF]
Frontiers in Immunology, 2021 Bacterial outer membrane vesicles (OMVs) are nanometer-scale, spherical vehicles released by Gram-negative bacteria into their surroundings throughout growth.
Shannon M. Collins, Angela C. Brown
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Bacterial Outer Membrane Vesicles Induce Plant Immune Responses [PDF]
Molecular Plant-Microbe Interactions, 2016 Gram-negative bacteria continuously pinch off portions of their outer membrane, releasing membrane vesicles. These outer membrane vesicles (OMVs) are involved in multiple processes including cell-to-cell communication, biofilm formation, stress tolerance,
Ofir Bahar +7 more
doaj +4 more sources
Outer membrane vesicle vaccines [PDF]
Seminars in Immunology, 2020 Outer Membrane Vesicles (OMV) have received increased attention in recent years as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis serogroup B have been extensively explored. Following the success of the MeNZB OMV vaccine in controlling an outbreak of N.
Francesca, Micoli, Calman A, MacLennan
openaire +2 more sources