Results 11 to 20 of about 162,214 (300)
Proteomics of Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles. [PDF]
PLoS ONE, 2015 Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins ...
Thomas Kieselbach +3 more
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Outer membrane vesicles: A bacterial-derived vaccination system
Frontiers in Microbiology, 2022 Outer membrane vesicles (OMVs) are non-living spherical nanostructures that derive from the cell envelope of Gram-negative bacteria. OMVs are important in bacterial pathogenesis, cell-to-cell communication, horizontal gene transfer, quorum sensing, and ...
Linda A. Lieberman
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Bacterial Outer Membrane Vesicles as Antibiotic Delivery Vehicles [PDF]
Frontiers in Immunology, 2021 Bacterial outer membrane vesicles (OMVs) are nanometer-scale, spherical vehicles released by Gram-negative bacteria into their surroundings throughout growth.
Shannon M. Collins, Angela C. Brown
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Bacterial Outer Membrane Vesicles Induce Plant Immune Responses [PDF]
Molecular Plant-Microbe Interactions, 2016 Gram-negative bacteria continuously pinch off portions of their outer membrane, releasing membrane vesicles. These outer membrane vesicles (OMVs) are involved in multiple processes including cell-to-cell communication, biofilm formation, stress tolerance,
Ofir Bahar +7 more
doaj +4 more sources
Outer membrane vesicle vaccines [PDF]
Seminars in Immunology, 2020 Outer Membrane Vesicles (OMV) have received increased attention in recent years as a vaccine platform against bacterial pathogens. OMV from Neisseria meningitidis serogroup B have been extensively explored. Following the success of the MeNZB OMV vaccine in controlling an outbreak of N.
Francesca, Micoli, Calman A, MacLennan
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Outer Membrane Vesicle Vaccine Platforms
BioDrugs, 2023 Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative bacteria during their growth and constitute an important virulence factor for bacteria, helping them to survive through harsh environmental conditions. Native OMVs, naturally-released from bacteria, are produced at a level too low for vaccine manufacturing, requiring ...
Micoli, Francesca +2 more
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Outer membrane vesicle vaccines for Neisseria gonorrhoeae [PDF]
Nature Reviews Urology, 2021 Multidrug-resistant Neisseria gonorrhoeae is a global health problem, and the development of a vaccine is considered essential for the effective control of gonorrhoea. The use of outer membrane vesicle vaccines to prevent N. gonorrhoeae infection has garnered considerable interest, and a recent study using a mouse model of experimental gonococcal ...
Evgeny A. Semchenko, Kate L. Seib
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Human Vaccines & Immunotherapeutics, 2012 Nowadays adjuvants are extensively used as immuno-stimulatory and immuno-modulatory compounds as components of subunit and combination vaccine formulations. The adjuvants of microbial origin are more frequently used among currently used licensed or experimental adjuvants.
Arfa, Moshiri +3 more
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Outer membrane vesicle-based intranasal vaccines
Current Opinion in Immunology, 2023 Delivery of vaccines via the mucosal route is regarded as the most effective mode of immunization to counteract infectious diseases that enter via mucosal tissues, including oral, nasal, pulmonary, intestinal, and urogenital surfaces. Mucosal vaccines not only induce local immune effector elements, such as secretory Immunoglobulin A (IgA) reaching the ...
Peter Van der Ley, Virgil EJC Schijns
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Gram-Negative Bacteria’s Outer Membrane Vesicles
Infection & Chemotherapy, 2023 Outer membrane vesicles (OMVs) are spherical bilayered nanoparticles derived from the outer layer of Gram-negative bacteria. Bacteria communicate with nearby bacteria, their environment, and the cells of their host by secreting OMVs, which are essential for their survival.
Jeong Yeon Kim +5 more
openaire +2 more sources