Results 31 to 40 of about 167,142 (325)

Characterization of Translocation Contact Sites Involved in the Import of Mitochondrial Proteins [PDF]

, 1987
Import of proteins into the mitochondrial matrix requires translocation across two membranes. Translocational intermediates of mitochondrial proteins, which span the outer and inner membrane simultaneously and thus suggest that translocation occurs in ...
Herzog, Volker, Neupert, Walter, Schwaiger, Martin   +2 more
core   +3 more sources

Bacterial Membrane Vesicles: Physiological Roles, Infection Immunology, and Applications

Advanced Science, 2023
Bacterial or fungal membrane vesicles, traditionally considered as microbial metabolic wastes, are secreted mainly from the outer membrane or cell membrane of microorganisms.
Yixiao Gan, Gang Zhao, Zhicheng Wang, Xingcai Zhang, Mei X. Wu, Min Lu   +5 more
doaj   +1 more source

Porphyromonas gingivalis Outer Membrane Vesicles Increase Vascular Permeability [PDF]

Journal of Dental Research, 2020
Periodontitis is increasingly associated with increased risk of cardiovascular and other systemic diseases. The Gram-negative anaerobe, Porphyromonas gingivalis, is a key periodontal pathogen, and several lines of evidence link the presence of this bacterium in the circulation with vascular disease.
Farrugia, C., Stafford, G.P., Murdoch, C.   +2 more
openaire   +4 more sources

Porphyromonas gingivalis Outer Membrane Vesicles Mediate Coaggregation and Piggybacking of Treponema denticola and Lachnoanaerobaculum saburreum

International Journal of Dentistry, 2013
Porphyromonas gingivalis sheds outer membrane vesicles that contain several virulence factors, including adhesins. In this study, we investigated the ability of P.
Daniel Grenier
doaj   +1 more source

Microbial biosynthesis of designer outer membrane vesicles [PDF]

Current Opinion in Biotechnology, 2014
Outer membrane vesicles (OMVs) are nanoscale proteoliposomes that are ubiquitously secreted by Gram-negative bacteria. Interest in these bioparticles has escalated over the years, leading to discoveries regarding their composition, production, and vaccine potential.
Jenny L, Baker, Linxiao, Chen, Joseph A, Rosenthal, David, Putnam, Matthew P, DeLisa   +4 more
openaire   +2 more sources

3-D Ultrastructure of O. tauri: Electron Cryotomography of an Entire Eukaryotic Cell [PDF]

, 2007
The hallmark of eukaryotic cells is their segregation of key biological functions into discrete, membrane-bound organelles. Creating accurate models of their ultrastructural complexity has been difficult in part because of the limited resolution of light
A Al-Amoudi, A Briegel, A Komeili, A Scheffel, AM van de Meene, AS Frangakis, AS Frangakis, B Farinas, B Palenik, B Storrie, C Courties, C Courties, C Suloway, CA Mannella, CA Mannella, CA Mannella, CA Mannella, CM Spahn, CV Iancu, CV Iancu, CW Akey, D Hoepfner, D Nicastro, D Stoffler, DN Mastronarde, E Derelle, E Shimoni, ER Wright, G Perkins, GC Johnston, GJ Jensen, GK Voeltz, GM Gaietta, GP Henderson, Grant J. Jensen, Gregory P. Henderson, HS Yoon, J Dubochet, J Kurner, JB Heymann, JL Hoog, JP Caviston, JP Ral, JR Warner, KL McDonald, LA Staehelin, LR Comolli, Lu Gan, M Beck, M Marko, MJ Chrétiennot-Dinet, O Medalia, PA Leong, Paul Digard, PE Purdue, Q Yang, QS Zheng, R Grimm, R Nevo, R Zadrag, RR Guillard, RT Mullen, S Robbens, S Subramaniam, SP Drummond, UC Vothknecht, V Lucic, V Stoppin, Y Shibata   +68 more
core   +11 more sources

Visualization of the exocyst complex dynamics at the plasma membrane of Arabidopsis thaliana [PDF]

, 2013
The exocyst complex, an effector of Rho and Rab GTPases, is believed to function as an exocytotic vesicle tether at the plasma membrane before soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex formation.
De Rycke, Riet, Drdová, Edita Janková, Fendrych, Matyáš, Nowack, Moritz, Pečenková, Tamara, Sekereš, Juraj, Synek, Lukáš, Žárský, Viktor   +7 more
core   +2 more sources

Engineering Planar Gram-Negative Outer Membrane Mimics Using Bacterial Outer Membrane Vesicles

Langmuir, 2023
AbstractAntibiotic resistance is a major challenge in modern medicine. The unique double membrane structure of gram-negative bacteria limits the efficacy of many existing antibiotics and adds complexity to antibiotic development by limiting transport of antibiotics to the bacterial cytosol. New methods to mimic this barrier would enable high-throughput
Aarshi N. Singh, Meishan Wu, Tiffany T. Ye, Angela C. Brown, Nathan J. Wittenberg   +4 more
openaire   +3 more sources

Outer membrane vesicles as platform vaccine technology [PDF]

Biotechnology Journal, 2015
AbstractOuter membrane vesicles (OMVs) are released spontaneously during growth by many Gram‐negative bacteria. They present a range of surface antigens in a native conformation and have natural properties like immunogenicity, self‐adjuvation and uptake by immune cells which make them attractive for application as vaccines against pathogenic bacteria ...
van der Pol, Leo, Stork, Michiel, van der Ley, Peter   +2 more
openaire   +2 more sources

Sites of Biosynthesis of Outer and Inner Membrane Proteins of Neurospora crassa Mitochondria [PDF]

, 1970
Outer and inner membranes of Neurospora crassa mitochondria were separated by the combined swelling, shrinking, sonication procedure. Membranes were characterized by electron microscopy and by marker enzyme activities.
Aasen A. J., Arrigoni O., Beattie D. S., Beattie D. S., Beisenherz G., Cassady W. E., Goodwin T. W., Harding R. W., Hawley E. S., Neupert W., Parsons D., Schnaitman G., Schott H.-H., Vogel H. J., Weiss H.   +14 more
core   +1 more source