Results 41 to 50 of about 3,494,909 (319)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Active vibration control of plate by active mass damper and negative acceleration feedback control algorithms

Journal of Low Frequency Noise, Vibration and Active Control, 2021
In this study, an active mass damper that could track desired displacement was considered as a controller to suppress vibrations of a plate. Multi-input multi-output modal-space negative acceleration feedback control algorithm and decentralized multi ...
Ji-Hwan Shin, Sangbo Han, Moon K Kwak
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

An iterative output feedback controller-design strategy for energy-to-peak structural vibration control

Journal of Asian Architecture and Building Engineering
To address the issue of inadequate control effect resulting from the challenge of measuring state feedback information comprehensively, this paper proposes an iterative output feedback energy-to-peak control method that solely depends on partial external
Qinghu Xu, Xiang Ruan, Jianhao Wei
doaj   +1 more source

Mean-Square Strong Stability and Stabilization of Discrete-Time Markov Jump Systems with Multiplicative Noises

Mathematics, 2022
In this paper, the mean-square strong stability and stabilization of discrete-time Markov jump systems are studied. Firstly, the definition of mean-square strong stability is given, and the necessary and sufficient conditions for mean-square strong ...
Zhiguo Yan, Fangxu Su
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Singular Perturbation Theory in Output Feedback Control of Pure-Feedback Systems

Iranian Journal of Electrical and Electronic Engineering, 2016
This paper studies output feedback control of pure-feedback systems with immeasurable states and completely non-affine property. Since availability of all the states is usually impossible in the actual process, we assume that just the system output is ...
M. Asadi, H. Toossian Shandiz
doaj  

Synthesis of Adaptive Gain Robust Output Feedback Controllers for a Class of Lipschitz Nonlinear Systems with Unknown Upper Bound of Uncertainty

Journal of Control Science and Engineering, 2012
We propose a new adaptive gain robust output feedback controller for a class of the Lipschitz nonlinear systems with unknown upper bound of uncertainty.
Hidetoshi Oya, Kojiro Hagino
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source