Results 11 to 20 of about 128,146 (288)

Assessment of the Route of Exposure to Ovalbumin and Cow’s Milk Proteins on the Induction of IgE Responses in BALB/c Mice

Biology, 2022
BALB/c mice can be orally sensitized to food proteins under acid suppressive medication, mimicking human exposure and triggering a human-like allergic immune response.
Feliznando Isidro Cárdenas-Torres, Francisco Cabrera-Chávez, Aldo Alejandro Arvizu-Flores, Lilian Karem Flores-Mendoza, Veronica Lopez-Teros, Humberto Astiazaran-Garcia, Martina Hilda Gracia-Valenzuela, Oscar Gerardo Figueroa-Salcido, Jesús Gilberto Arámburo-Gálvez, Noé Ontiveros   +9 more
doaj   +1 more source

Immunogenicity of targeted lentivectors [PDF]

, 2014
To increase the safety and possibly efficacy of HIV-1 derived lentivectors (LVs) as an anti-cancer vaccine, we recently developed the Nanobody (Nb) display technology to target LVs to antigen presenting cells (APCs).
Adotévi, Bennett, Bevan, Bhardwaj, Bhardwaj, Bhardwaj, Blander, Bonehill, Bonehill, Breckpot, Breckpot, Breckpot, Charleston, Chuah, Collins, Collins, Collins, Collins, Cosset, Diebold, Donckier, Eggermont, Enk, Figdor, Gajewski, Garcia, Groettrup, Inaba, Kast, Lahoutte, Lévy, McCullough, Medzhitov, Melief, Mellman, Mortha, Moser, Moser, Munn, Naldini, Neyns, Noguiez-Hellin, Nussenzweig, Palena, Raes, Reis e Sousa, Reiser, Reiser, Richardson, Romani, Roncarolo, Sakuma, Schroyens, Semesyuk, Song, Storm, Thielemans, Thielemans, Thielemans, Thielemans, Torretta, Turk, Van Kooyk, Wang, Wang, Yamaguchi, Yewdell, Yu   +67 more
core   +3 more sources

Mycobacterium tuberculosis–Specific Antigen Rv3619c Effectively Alleviates Allergic Asthma in Mice

Frontiers in Pharmacology, 2020
Despite significant advances, asthma remains a cause of premature death, and current treatments are suboptimal. Antigen-specific Th2 cells and their cytokines are primary mediators of the pathophysiological changes seen in asthma.
Hussain A. Safar, Ahmed Z. El-Hashim, Hanady Amoudy, Abu Salim Mustafa   +3 more
doaj   +1 more source

Determination of the critical molar mass of ovalbumin oligomers degraded by ultrasound [PDF]

Journal of the Serbian Chemical Society, 2000
An experimental method has been developed which enables the determination of the critical molar mass (Mmc) of ovalbumin oligomers degraded by ultrasound of known frequency.
Filipović Dragana, Radojčić Marija, Milosavljević Bratoljub H.   +2 more
doaj   +1 more source

Self-assembling nanoparticles containing dexamethasone as a novel therapy in allergic airways inflammation. [PDF]

, 2013
Nanocarriers can deliver a wide variety of drugs, target them to sites of interest, and protect them from degradation and inactivation by the body. They have the capacity to improve drug action and decrease undesirable systemic effects.
Bratt, Jennifer M, Franzi, Lisa M, Kenyon, Nicholas J, Lam, Kit S, Lee, Joyce, Luo, Juntao, Zeki, Amir A   +6 more
core   +2 more sources

Theragnostic Glycol Chitosan-Conjugated Gold Nanoparticles for Photoacoustic Imaging of Regional Lymph Nodes and Delivering Tumor Antigen to Lymph Nodes

Nanomaterials, 2021
Lymph node mapping is important in cancer immunotherapy because the morphology of lymph nodes is one of the crucial evaluation criteria of immune responses.
In-Cheol Sun, SeongHoon Jo, Diego Dumani, Wan Su Yun, Hong Yeol Yoon, Dong-Kwon Lim, Cheol-Hee Ahn, Stanislav Emelianov, Kwangmeyung Kim   +8 more
doaj   +1 more source

Poly(2-propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles as a targeted antigen delivery system to direct either CD4+ or CD8+ T cell activation. [PDF]

, 2017
Poly(lactic-co-glycolic acid) (PLGA) based microparticles (MPs) are widely investigated for their ability to load a range of molecules with high efficiency, including antigenic proteins, and release them in a controlled manner.
Bracho-Sanchez, Evelyn, Carstens, Matthew R, Duvall, Craig L, Fernando, Lawrence P, Keselowsky, Benjamin G, Lewis, Jamal S, Yang, Lirong   +6 more
core   +1 more source

Echinochrome Ameliorates Physiological, Immunological, and Histopathological Alterations Induced by Ovalbumin in Asthmatic Mice by Modulating the Keap1/Nrf2 Signaling Pathway

Marine Drugs, 2023
Asthma is a persistent inflammatory disease of the bronchi characterized by oxidative stress, airway remodeling, and inflammation. Echinochrome (Ech) is a dark-red pigment with antioxidant and anti-inflammatory activities.
Islam Ahmed Abdelmawgood, Noha Ahmed Mahana, Abeer Mahmoud Badr, Ayman Saber Mohamed, Abdeljalil Mohamed Al Shawoush, Tarek Atia, Amir Elhadi Abdelrazak, Hader I. Sakr   +7 more
doaj   +1 more source

Induction of Thymic Stromal Lymphopoietin Production by Nonanoic Acid and Exacerbation of Allergic Inflammation in Mice

Allergology International, 2013
Background: Thymic stromal lymphopoietin (TSLP) plays critical roles in the induction and exacerbation of allergic diseases. We tested various chemicals in the environment and found that xylene and 1,2,4-trimethylbenzene induced the production of TSLP in
Saori Yamashita, Ryosuke Segawa, Nozomi Satou, Masahiro Hiratsuka, Warren J Leonard, Noriyasu Hirasawa   +5 more
doaj   +1 more source

MHC class II-restricted antigen presentation by plasmacytoid dendritic cells drives proatherogenic T cell immunity [PDF]

, 2014
Background—Plasmacytoid dendritic cells (pDCs) bridge innate and adaptive immune responses and are important regulators of immuno-inflammatory diseases. However, their role in atherosclerosis remains elusive.
Ait-Oufella, Hafid, Baker, Lauren L., Cambrook, Helen, Finigan, Alison J., Grassia, Gianluca, Hansson, Göran K., Harrison, James E., Hugues, Stéphanie, Ludewig, Burkhard, Maffia, Pasquale, Mallat, Ziad, Masters, Leanne M., Murphy, Deirdre, Reith, Walter, Reizis, Boris, Sabir, Suleman, Sage, Andrew P.   +16 more
core   +2 more sources