Results 161 to 170 of about 47,234 (246)

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Pharmacological effects and mechanisms of medicine food homology species and active ingredients in ameliorating ovarian aging. [PDF]

Front Nutr
Chen J, Li X, Lai X, Xu R, Liu Z, Xing J, Yang L, Zhang Q.   +7 more
europepmc   +1 more source

Essential embryology for the Canadian pathologists’ assistant

Anatomical Sciences Education, EarlyView.
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci, William Tsui, Fang‐I Lu, Avrum I. Gotlieb, Danielle C. Bentley   +4 more
wiley   +1 more source

Age-related mitochondrial energy metabolism reprogramming occurs in granulosa cells during ovarian aging. [PDF]

Front Endocrinol (Lausanne)
Shi M, Jia Z, Yang X, Qi W, Sun X, Li Y, Wang P, Guo Y.   +7 more
europepmc   +1 more source

How the HTAR will contribute to a value‐based decision‐making for medicinal products across the EU

British Journal of Clinical Pharmacology, EarlyView.
The European Union Health Technology Regulation 2021/2282 (HTAR) introduces joint assessment of health technologies (including medicinal products and medical devices) across EU Member States. It was signed into law in 2021 and came into full force in January 2025.
Roisin Adams, Michal Stanak
wiley   +1 more source

Ovarian aging: pathophysiology and recent developments in maintaining ovarian reserve. [PDF]

Front Endocrinol (Lausanne)
Hirano M, Onodera T, Takasaki K, Takahashi Y, Ichinose T, Nishida H, Hiraike H, Nagasaka K.   +7 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Self-Organizing Ovarian Somatic Organoids Preserve Cellular Heterogeneity and Reveal Cellular Contributions to Ovarian Aging. [PDF]

Aging Cell
Dipali SS, Converse A, Gowett MQ, Kamat P, Zaniker EJ, Fennell A, Chou T, Pritchard MT, Zelinski M, Phillip JM, Duncan FE.   +10 more
europepmc   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Apigenin Prevents Ovarian Aging by Regulating Ca²⁺-Mediated Endoplasmic Reticulum Stress in Laying Chickens. [PDF]

Antioxidants (Basel)
Gao W, Dong J, Xiao Y, Cai X, Yang Z, Zeng W, Zhang C, Mi Y.   +7 more
europepmc   +1 more source