Results 31 to 40 of about 47,234 (246)
Frontiers in Endocrinology, 2021 The number of mitochondria in the oocyte along with their functions (e.g., energy production, scavenger activity) decline with age progression. Such multifaceted functions support several processes during oocyte maturation, ranging from energy supply to ...
Marco Colella +11 more
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Neuroendocrinology and ovarian aging
Gynecological Endocrinology, 2012 The ovarian aging, a dynamic process that precedes the clinical manifestations of menopause, can be assessed using ovarian reserve biomarkers. It is well-known that reproduction during the later years of reproductive life has known limitations that challenge the success of assisted reproduction.
Devoto, Luigi +3 more
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Polyamines in Ovarian Aging and Disease
International Journal of Molecular Sciences, 2023 Ovarian aging and disease-related decline in fertility are challenging medical and economic issues with an increasing prevalence. Polyamines are a class of polycationic alkylamines widely distributed in mammals. They are small molecules essential for cell growth and development.
Bo Kang +7 more
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Early ovarian ageing: a hypothesis: What is early ovarian ageing? [PDF]
Human Reproduction, 2003 A concept of early ovarian ageing has been advanced. This theory suggests that some women will experience problems of fecundity at an early age given that the age of menopause is earlier for some women, and there is a fixed time of accelerated atresia leading up to menopause.
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Ovarian aging: mechanisms and intervention strategies
Medical Review, 2022 Ovarian reserve is essential for fertility and influences healthy aging in women. Advanced maternal age correlates with the progressive loss of both the quantity and quality of oocytes. The molecular mechanisms and various contributing factors underlying
Zhu Zhengmao, Xu Wanxue, Liu Lin
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Biomedicines, 2022 The primary definition of ovarian aging refers to the loss of follicles. Moreover, the aging of the microenvironment in ovaries, specifically affecting the follicles, may reveal deterioration with advancing age.
Verónica Díaz-Hernández +3 more
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The stromal microenvironment and ovarian aging: mechanisms and therapeutic opportunities
Journal of Ovarian Research, 2023 For decades, most studies of ovarian aging have focused on its functional units, known as follicles, which include oocytes and granulosa cells. However, in the ovarian stroma, there are a variety of somatic components that bridge the gap between general ...
Lu Shen +3 more
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Cardiovascular health and ovarian aging [PDF]
Fertility and Sterility, 2018 One in three American women will die from cardiovascular disease (CVD), making it the leading cause of death among women in the United States. Traditionally, CVD has been seen as a disease of postmenopausal women, yet increasingly, risk factors for CVD are being characterized earlier.
Molly M, Quinn, Marcelle I, Cedars
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The Inflammasome Contributes to Depletion of the Ovarian Reserve During Aging in Mice
Frontiers in Cell and Developmental Biology, 2021 Ovarian aging is a natural process characterized by follicular depletion and a reduction in oocyte quality, resulting in loss of ovarian function, cycle irregularity and eventually infertility and menopause.
Carolina Lliberos +3 more
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An Update on Ovarian Aging and Ovarian Reserve Tests.
International journal of fertility & sterility, 2016 Ovaries are the female organs that age more quickly than other tissues such as the uterus, the pituitary gland or pancreas. Different from males, an interesting question is why and how the females lose fertility so rapidly. During the aging process, both the number and quality of the oocytes in the ovaries decrease and reach to a point beyond that no ...
Amanvermez, Ramazan, Tosun, Migraci
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