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Mechanisms of ovarian aging in women: a review
Ovarian aging is a natural and physiological aging process characterized by loss of quantity and quality of oocyte or follicular pool. As it is generally accepted that women are born with a finite follicle pool that will go through constant decline ...
Xiangfei Wang +2 more
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Biomaterials and advanced technologies for the evaluation and treatment of ovarian aging
Ovarian aging is characterized by a progressive decline in ovarian function. With the increase in life expectancy worldwide, ovarian aging has gradually become a key health problem among women.
Meng Wu +16 more
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The role of oxidative stress in ovarian aging: a review
Ovarian aging refers to the process by which ovarian function declines until eventual failure. The pathogenesis of ovarian aging is complex and diverse; oxidative stress (OS) is considered to be a key factor.
Fei Yan +7 more
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Single-cell transcriptomic atlas of goat ovarian aging
Background The ovaries are one of the first organs that undergo degenerative changes earlier in the aging process, and ovarian aging is shown by a decrease in the number and quality of oocytes.
Dejun Xu +7 more
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The emerging role of lysine succinylation in ovarian aging
Background Ovarian aging is a process of decline in its reserve leading to ovary dysfunction and even reduced health quality in offspring. However, aging-related molecular pathways in the ovary remain obscure.
Meiling Le +9 more
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Ovarian reserve is a key factor in the reproductive function of the ovaries. Ovarian aging is characterized by a gradual decline in the quantity and quality of follicles.
XueLai He +7 more
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Ovarian aging and premature ovarian failure
Physiological reproductive aging occurs as a result of a decrease in the number and quality of oocytes in ovarian cortex follicles. Although the reason for the decrease in the quality of the pool and follicular oocytes is not fully understood, endocrine, paracrine, genetic, and metabolic factors are thought to be effective.
Yavuz Emre, Sükür +2 more
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Ovarian aging leads to reproductive and endocrine dysfunction, causing the disorder of multiple organs in the body and even declined quality of offspring’s health.
Lingwei Ma +6 more
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Anti-Müllerian hormone and ovarian aging [PDF]
The ovary is the source of oocytes and supplier of sex steroid hormones. Being responsible for female fertility and endocrine homeostasis, the progressive decline in the quantity and quality of str...
Erel, C. Tamer, Ozcivit, Ipek B.
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The biological state of the ovum remains the key element in normal reproduction. Age-related decrease in the number of oocytes, as well as disturbed neuroendocrine function of the ovary and lesions in the uterus, contribute to reduced fertility. Decreasing number of ovarian follicles is accompanied by reduction of their quality including mainly ...
Monika, Szafarowska, Małgorzata, Jerzak
openaire +2 more sources

