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Epithelial ovarian cancer [PDF]
The Lancet, 2019 Epithelial ovarian cancer generally presents at an advanced stage and is the most common cause of gynaecological cancer death. Treatment requires expert multidisciplinary care. Population-based screening has been ineffective, but new approaches for early diagnosis and prevention that leverage molecular genomics are in development.
S, Lheureux +3 more
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NCCN Guidelines® Insights: Ovarian Cancer, Version 3.2022.
The Journal of the National Comprehensive Cancer Network, 2022 Epithelial ovarian cancer is the leading cause of death from gynecologic cancer in the United States, with less than half of patients living >5 years following diagnosis.
D. Armstrong +37 more
semanticscholar +1 more source
Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.
The Journal of the National Comprehensive Cancer Network, 2021 Epithelial ovarian cancer is the leading cause of death from gynecologic cancer in the United States and is the country's fifth most common cause of cancer mortality in women.
D. Armstrong +33 more
semanticscholar +1 more source
Worldwide Burden, Risk Factors, and Temporal Trends of Ovarian Cancer: A Global Study
Cancers, 2022 Simple Summary Ovarian cancer was the third most common gynecological cancer globally in 2020. Ovarian carcinoma is the most common type of ovarian cancer, comprising over 90% of all ovarian cancer cases.
Junjie Huang +11 more
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CA: A Cancer Journal for Clinicians, 1986 Early diagnosis is the most effective means of reducing the currently high mortality rate associated with ovarian cancer. The palpation of what appears to be a normal size ovary in a premenopausal woman suggests an ovarian tumor in a postmenopausal woman.
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Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. [PDF]
, 2020 Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers.
Axelrod, Joshua +14 more
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Molecular mechanisms of platinum-based chemotherapy resistance in ovarian cancer
Oncology Report, 2022 Cisplatin is one of the most effective chemotherapy drugs for ovarian cancer, but resistance is common. The initial response to platinum-based chemotherapy is as high as 80%, but in most advanced patients, final relapse and death are caused by acquired ...
Ling Yang +5 more
semanticscholar +1 more source
Molecular Biomarkers for the Early Detection of Ovarian Cancer
International Journal of Molecular Sciences, 2022 Ovarian cancer is the deadliest gynecological cancer, leading to over 152,000 deaths each year. A late diagnosis is the primary factor causing a poor prognosis of ovarian cancer and often occurs due to a lack of specific symptoms and effective biomarkers
Ruiqian Zhang +3 more
semanticscholar +1 more source
Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis
Journal of Ovarian Research, 2020 Background A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity.
Jeremi Laski +5 more
doaj +1 more source
Subtypes of Ovarian Cancer and Ovarian Cancer Screening [PDF]
Diagnostics, 2017 Ovarian cancer is the foremost cause of gynecological cancer death in the developed world, as it is usually diagnosed at an advanced stage. In this paper we discuss current issues, the efficacy and problems associated with ovarian cancer screening, and compare the characteristics of ovarian cancer subtypes. There are two types of ovarian cancer: Type I
Masafumi Koshiyama +2 more
openaire +3 more sources