Results 11 to 20 of about 5,317,572 (397)

Ovarian Cancer [PDF]

open access: goldCA: A Cancer Journal for Clinicians, 1974
H R, Barber, E A, Graber, , KwonTH
openaire   +3 more sources

Gain-of-function p53R175H blocks apoptosis in a precursor model of ovarian high-grade serous carcinoma

open access: yesScientific Reports, 2023
Ovarian high-grade serous carcinoma (HGSC) is a highly lethal malignancy for which early detection is a challenge and treatment of late-stage disease is ineffective. HGSC initiation involves exfoliation of fallopian tube epithelial (FTE) cells which form
Jacob Haagsma   +5 more
doaj   +1 more source

Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.

open access: yesThe Journal of the National Comprehensive Cancer Network, 2021
Epithelial ovarian cancer is the leading cause of death from gynecologic cancer in the United States and is the country's fifth most common cause of cancer mortality in women.
D. Armstrong   +33 more
semanticscholar   +1 more source

Overlapping gene dependencies for PARP inhibitors and carboplatin response identified by functional CRISPR-Cas9 screening in ovarian cancer

open access: yesCell Death and Disease, 2022
PARP inhibitors (PARPi) have revolutionized the therapeutic landscape of epithelial ovarian cancer (EOC) treatment with outstanding benefits in regard to progression-free survival, especially in patients either carrying BRCA1/2 mutations or harboring ...
Ricardo Coelho   +8 more
doaj   +1 more source

Worldwide Burden, Risk Factors, and Temporal Trends of Ovarian Cancer: A Global Study

open access: yesCancers, 2022
Simple Summary Ovarian cancer was the third most common gynecological cancer globally in 2020. Ovarian carcinoma is the most common type of ovarian cancer, comprising over 90% of all ovarian cancer cases.
Junjie Huang   +11 more
semanticscholar   +1 more source

Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis

open access: yesJournal of Ovarian Research, 2020
Background A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity.
Jeremi Laski   +5 more
doaj   +1 more source

Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. [PDF]

open access: yes, 2020
Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers.
Axelrod, Joshua   +14 more
core   +1 more source

Ovarian Cancer [PDF]

open access: yesCA: A Cancer Journal for Clinicians, 1986
Early diagnosis is the most effective means of reducing the currently high mortality rate associated with ovarian cancer. The palpation of what appears to be a normal size ovary in a premenopausal woman suggests an ovarian tumor in a postmenopausal woman.
openaire   +6 more sources

Ovarian Cancer [PDF]

open access: yesAnnual Review of Public Health, 1996
Ovarian cancer incidence rates are highest and stable in white populations; in Asia previously low incidence rates may be increasing. Most cases present with disseminated disease, and mortality rates remain high despite the use of aggressive polychemotherapy.
openaire   +4 more sources

Subtypes of Ovarian Cancer and Ovarian Cancer Screening [PDF]

open access: yesDiagnostics, 2017
Ovarian cancer is the foremost cause of gynecological cancer death in the developed world, as it is usually diagnosed at an advanced stage. In this paper we discuss current issues, the efficacy and problems associated with ovarian cancer screening, and compare the characteristics of ovarian cancer subtypes. There are two types of ovarian cancer: Type I
Masafumi Koshiyama   +2 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy