Results 11 to 20 of about 445,411 (307)
Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis
Journal of Ovarian Research, 2020 Background A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity.
Jeremi Laski +5 more
doaj +1 more source
L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Communications Biology, 2022 L1CAM is implicated as an important factor that enables early fallopian tube cancer precursors to seed the ovary by promoting cell survival through extracellular matrix signaling, thereby facilitating ovarian cancer growth.
Kai Doberstein +13 more
doaj +1 more source
BMC Cancer, 2017 Background Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heterogeneity, which can hinder successful treatment strategies.
Jessica G. Tong +7 more
doaj +1 more source
Insights into high-grade serous carcinoma pathobiology using three-dimensional culture model systems
Journal of Ovarian Research, 2023 Epithelial ovarian cancer (EOC) research has become more complex as researchers try to fully understand the metastatic process. Especially as we delve into the concept of tumour dormancy, where cells transition between proliferative and dormant states to
Emily Tomas, Trevor G. Shepherd
doaj +1 more source
PLoS Medicine, 2012 BackgroundOnly about half the studies that have collected information on the relevance of women's height and body mass index to their risk of developing ovarian cancer have published their results, and findings are inconsistent.
Collaborative Group on Epidemiological Studies of Ovarian Cancer
doaj +1 more source
Clinical Evaluation of BRCA1/2 Mutation in Mexican Ovarian Cancer Patients
Translational Oncology, 2020 Ovarian cancer (OC) is an important cause of gynecologic cancer-related deaths. In Mexico, around 4700 new cases of OC are diagnosed per year and it represents the second cause of gynecological cancer mortality with more than 2700 deaths.
Dolores Gallardo-Rincón +11 more
doaj +1 more source
Acta Oncologica, 1996 This synthesis of the literature on radiotherapy for cancer originating in the ovaries is based on 74 scientific articles, including 12 randomized studies, 18 prospective studies, and 36 retrospective studies. These studies involve 6,140 patients. Treatment for patients at early stages of ovarian cancer (stages I and II) is surgery.
openaire +4 more sources
Current Oncology, 2022 Prior to 1997, ovarian cancer (OC) was a ‘poor target’ for patient advocacy. At that time, there were only three OC researchers in Canada, little information available for women diagnosed, and no community of survivors existed.
Elisabeth Baugh +4 more
doaj +1 more source
DNA-PK Mediates AKT Activation and Apoptosis Inhibition in Clinically Acquired Platinum Resistance
Neoplasia: An International Journal for Oncology Research, 2011 Clinical resistance to chemotherapy is a frequent event in cancer treatment and is closely linked to poor outcome. High-grade serous (HGS) ovarian cancer is characterized by p53 mutation and high levels of genomic instability. Treatment includes platinum-
Euan A. Stronach +6 more
doaj +1 more source
npj Precision Oncology, 2021 Endometrioid ovarian carcinoma (EnOC) is an under-investigated ovarian cancer type. Recent studies have described disease subtypes defined by genomics and hormone receptor expression patterns; here, we determine the relationship between these subtyping ...
Robert L. Hollis +12 more
doaj +1 more source