Results 21 to 30 of about 720,445 (328)
CA: A Cancer Journal for Clinicians, 1986 Early diagnosis is the most effective means of reducing the currently high mortality rate associated with ovarian cancer. The palpation of what appears to be a normal size ovary in a premenopausal woman suggests an ovarian tumor in a postmenopausal woman.
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Activated CAMKKβ-AMPK signaling promotes autophagy in a spheroid model of ovarian tumour metastasis
Journal of Ovarian Research, 2020 Background A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity.
Jeremi Laski +5 more
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Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. [PDF]
, 2020 Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers.
Axelrod, Joshua +14 more
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Annual Review of Public Health, 1996 Ovarian cancer incidence rates are highest and stable in white populations; in Asia previously low incidence rates may be increasing. Most cases present with disseminated disease, and mortality rates remain high despite the use of aggressive polychemotherapy.
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Subtypes of Ovarian Cancer and Ovarian Cancer Screening [PDF]
Diagnostics, 2017 Ovarian cancer is the foremost cause of gynecological cancer death in the developed world, as it is usually diagnosed at an advanced stage. In this paper we discuss current issues, the efficacy and problems associated with ovarian cancer screening, and compare the characteristics of ovarian cancer subtypes. There are two types of ovarian cancer: Type I
Masafumi Koshiyama +2 more
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L1CAM is required for early dissemination of fallopian tube carcinoma precursors to the ovary
Communications Biology, 2022 L1CAM is implicated as an important factor that enables early fallopian tube cancer precursors to seed the ovary by promoting cell survival through extracellular matrix signaling, thereby facilitating ovarian cancer growth.
Kai Doberstein +13 more
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Ovarian cancer screening [PDF]
Cancer, 1991 AbstractBackground. Despite advances in evaluation and treatment, ovarian cancer mortality has decreased minimally during the past two decades. Most patients have advanced‐stage disease at diagnosis, and the prognosis is poor. As a result, there has been increasing interest in the development of methods for the early detection of ovarian cancer.
Edward J. Pavlik +3 more
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Inflammation and Ovarian Cancer [PDF]
Cytokine, 2012 Epithelial ovarian cancer (EOC) is a highly lethal gynecological cancer for which overall prognosis has remained poor over the past few decades. A number of theories have been postulated in an effort to explain the etiology of EOC. Noteworthy, these theories likely are not mutually exclusive, as they all converge more or less on the role of ...
Maccio' A, MADEDDU, CLELIA
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BMC Cancer, 2017 Background Epithelial ovarian cancer exhibits extensive interpatient and intratumoral heterogeneity, which can hinder successful treatment strategies.
Jessica G. Tong +7 more
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Insights into high-grade serous carcinoma pathobiology using three-dimensional culture model systems
Journal of Ovarian Research, 2023 Epithelial ovarian cancer (EOC) research has become more complex as researchers try to fully understand the metastatic process. Especially as we delve into the concept of tumour dormancy, where cells transition between proliferative and dormant states to
Emily Tomas, Trevor G. Shepherd
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