Results 31 to 40 of about 5,317,572 (397)
A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
Science, 1994 A strong candidate for the 17q-linked BRCA1 gene, which influences susceptibility to breast and ovarian cancer, has been identified by positional cloning methods.
Y. Miki +44 more
semanticscholar +1 more source
The m6A reader YTHDF1 promotes ovarian cancer progression via augmenting EIF3C translation
Nucleic Acids Research, 2020 N 6-Methyladenosine (m6A) is the most abundant RNA modification in mammal mRNAs and increasing evidence suggests the key roles of m6A in human tumorigenesis.
Tao Liu +17 more
semanticscholar +1 more source
PLoS Medicine, 2012 BackgroundOnly about half the studies that have collected information on the relevance of women's height and body mass index to their risk of developing ovarian cancer have published their results, and findings are inconsistent.
Collaborative Group on Epidemiological Studies of Ovarian Cancer
doaj +1 more source
Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.
New England Journal of Medicine, 2019 BACKGROUND Niraparib, an inhibitor of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP), has been associated with significantly increased progression-free survival among patients with recurrent ovarian cancer after platinum-based chemotherapy ...
A. González-Martín +29 more
semanticscholar +1 more source
Treatment of epithelial ovarian cancer
British medical journal, 2020 Ovarian cancer is the third most common gynecologic malignancy worldwide but accounts for the highest mortality rate among these cancers. A stepwise approach to assessment, diagnosis, and treatment is vital to appropriate management of this disease ...
L. Kuroki, S. Guntupalli
semanticscholar +1 more source
Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer.
New England Journal of Medicine, 2019 BACKGROUND Olaparib has shown significant clinical benefit as maintenance therapy in women with newly diagnosed advanced ovarian cancer with a BRCA mutation.
I. Ray-Coquard +29 more
semanticscholar +1 more source
The association between hysterectomy and ovarian cancer risk: A population-based record-linkage study [PDF]
, 2019 Background: Recent studies have called into question the long-held belief that hysterectomy without oophorectomy protects against ovarian cancer. This population-based longitudinal record-linkage study aimed to explore this relationship, overall and by ...
Dixon-Suen, Suzanne C +5 more
core +2 more sources
npj Precision Oncology, 2021 Endometrioid ovarian carcinoma (EnOC) is an under-investigated ovarian cancer type. Recent studies have described disease subtypes defined by genomics and hormone receptor expression patterns; here, we determine the relationship between these subtyping ...
Robert L. Hollis +12 more
doaj +1 more source
CA125 and Ovarian Cancer: A Comprehensive Review
Cancers, 2020 Simple Summary CA125 has been the most promising biomarker for screening ovarian cancer; however, it still does not have an acceptable accuracy in population-based screening for ovarian cancer.
Parsa Charkhchi +5 more
semanticscholar +1 more source
Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model [PDF]
, 2012 Ovarian cancer is the leading cause of cancer related deaths in women. Genetic alterations including overexpression of EGFR play a crucial role in ovarian carcinogenesis.
Joseph Alan Bauer +4 more
core +3 more sources