Results 41 to 50 of about 5,217,497 (361)
Medical treatment of early stage and rare histological variants of epithelial ovarian cancer [PDF]
, 2015 Epithelial ovarian cancer is often considered a single pathological entity, but increasing evidence suggests that it is rather a group of different
neoplasms, each with unique pathological characteristics, molecular features, and clinical behaviours ...Biglia, Nicoletta, CODACCI PISANELLI, Giovanni, Colombo, Nicoletta, Cont, Nicoletta Tomasi, D'Alonzo, Marta, Ferrero, Annamaria, Peccatori, Fedro Alessandro +6 morecore +3 more sourcesGermline and Somatic Tumor Testing in Epithelial Ovarian Cancer: ASCO Guideline.
Journal of Clinical Oncology, 2020 PURPOSE
To provide recommendations on genetic and tumor testing for women diagnosed with epithelial ovarian cancer based on available evidence and expert consensus.P. Konstantinopoulos, B. Norquist, C. Lacchetti, D. Armstrong, R. Grisham, P. Goodfellow, E. Kohn, D. Levine, Joyce F. Liu, K. Lu, Dee Sparacio, C. Annunziata +11 moresemanticscholar +1 more sourceBRCA2 polymorphic stop codon K3326X and the risk of breast, prostate, and ovarian cancers [PDF]
, 2016 Background: The K3326X variant in BRCA2 (BRCA2*c.9976A>T; p.Lys3326*; rs11571833) has been found to be associated with small increased risks of breast cancer.Agnarsson, Bjarni A., Aittomäki, Kristiina, Andrulis, Irene L., Anton-Culver, Hoda, Antoniou, Antonis C., Bandera, Elisa V., Banerjee, Susana, Barile, Monica, Barrowdale, Daniel, Beckman, Matthias W., Beeghly-Fadiel, Alicia, Benitez, Javier, Berchuck, Andrew, Bjorge, Line, Blomqvist, Carl, Bogdanova, Natalia V., Bojesen, Stig E., Bolla, Manjeet K., Borg, Ake, Borresen-Dale, Anne-Lise, Brauch, Hiltrud, Brenner, Hermann, Broeks, Annegien, Bruinsma, Fiona, Brunet, Joan, Brüning, Thomas, Burwinkel, Barbara, Butterbach, Katja, Butzow, Ralf, Buys, Saundra S., Cai, Hui, Campbell, Ian G., Cannioto, Rikki, Castillo, Danielle, Chan, Salina B., Chang-Claude, Jenny, Chenevix-Trench, Georgia, Claes, Kathleen B. M., Collavoli, Anita, Cook, Linda S., Couch, Fergus J., Cox, Angela, Cramer, Daniel, Cross, Simon S., Cunningham, Julie M., Czene, Kamila, Daly, Mary B., Damiola, Francesca, Darabi, Hatef, de la Hoya, Miguel, Dennis, Joe, Devilee, Peter, Diez, Orland, Ding, Yuan Chun, Doherty, Jennifer A., Domchek, Susan M., Dorfling, Cecilia M., Dunning, Alison M., Dörk, Thilo, Easton, Douglas F., Eccles, Diana M., Ellis, Steve, Eunjung, Lee, Fasching, Peter A., Feng, Bingjian, Figueroa, Jonine, Flesch-Janys, Dieter, Fletcher, Olivia, Flyger, Henrik, Foretova, Lenka, Fostira, Florentia, Friedman, Eitan, Frost, Debra, Ganz, Patricia N., Gao, Yu-Tang, Garber, Judy, García-Closas, Montserrat, Gayther, Simon, Gerdes, Anne-Marie, Giles, Graham G., Glasspool, Rosalind, Godwin, Andrew K., Goldberg, Mark S., Goldgar, David E., González-Neira, Anna, Goode, Ellen L., Goodman, Marc T., Greene, Mark H., Gronwald, Jacek, Guénel, Pascal, Hahnen, Eric, Haiman, Christopher A., Hall, Per, Hallberg, Emily, Hamann, Ute, Hansen, Thomas V. O., Hart, Steven N., Healey, Sue, Heitz, Florian, Henderson, Brian E., Henriksson, Karin, Hildebrant, Michelle A. T., Hogdall, Claus, Hogdall, Estrid, Hogervorst, Frans B. L., Hopper, John L., Hosono, Satoyo, Hulick, Peter J., Imyanitov, Evgeny N., Isaacs, Claudine, Jakubowska, Anna, James, Paul A., Janavicius, Ramunas, Jensen, Allen, John, Esther M., Johnson, Nichola, Jones, Michael, Kabisch, Maria, Karlan, Beth Y., Khan, Sofia, Kiemeney, Lambertus A., Kjaer, Susanne K., Knight, Julia A., Konstantopoulou, Irene, Koppert, Linetta B., Kosma, Veli-Matti, Kristensen, Vessela, Kupryjanczyk, Jolanta, Kwong, Ava, Laitman, Yael, Lambrechts, Diether, Lazaro, Conxi, Le, Nhu, Lester, Jenny, Levine, Douglas, Li, Jingmei, Liang, Dong, Lindblom, Annika, Loud, Jennifer T., Lu, Karen H., Lubinski, Jan, Mai, Phuong L., Mannermaa, Arto, Manoukian, Siranoush, Margolin, Sara, Marme, Frederik, Massuger, Leon F. A. G., Matsuo, Keitaro, Maugard, Christine, Mazoyer, Sylvie, McGuffog, Lesley, McNeish, Iain, Meeks, Huong D., Meindl, Alfons, Menon, Usha, Michailidou, Kyriaki, Milne, Roger L., Modugno, Francesmary, Moes-Sosnowska, Joanna, Montagna, Marco, Monteiro, Alvaro N. A., Moysich, Kirsten B., Narod, Steven, Nathanson, Katherine L., Ness, Roberta, Neuhausen, Susan L., Nevanlinna, Heli, Neven, Patrick, Nussbaum, Robert L., Offit, Kenneth, Olah, Edith, Oliani, Cristina, Olopade, Olufunmilayo I., Olson, Janet E., Olson, Sara H., Osorio, Ana, Park, Sue K., Pasini, Barbara J., Pearce, Leigh, Pedersen, Inge Sokilde, Peissel, Bernard, Peixoto, Ana, Pejovic, Tanja, Pelttari, Liisa M., Peterlongo, Paolo, Pharoah, Paul D. P., Phelan, Catherine M., Piedmonte, Marion, Poole, Elizabeth M., Pylkäs, Katri, Radice, Paolo, Ramus, Susan J., Rantala, Johanna, Rappaport-Feurhauser, Christine, Rennert, Gad, Riboli, Elio, Risch, Harvey, Robson, Mark, Rossing, Mary Anne, Rudolph, Anja, Salvesen, Helga B., Sawyer, Elinor J., Schildkraut, Joellen, Schmidt, Marjanka K., Schoemaker, Minouk J., Segura, Pedro Perez, Senter, Leigha, Shah, Mitul, Shimelis, Hermela, Siddiquil, Nadeem, Sieh, Weiva, Simard, Jacques, Singer, Christian F., Sinilnikova, Olga M., Slager, Susan, Song, Honglin, Soucy, Penny, Southey, Melissa C., Spurdle, Amanda B., Stoppa-Lyonnet, Dominique, Swerdlow, Anthony, Teixeira, Manuel R., Teo, Soo Hwang, Terry, Kathryn L., Terry, Mary Beth, Tesoriero, Andrea, Thomassen, Mads, Thompson, Pamela J., Tihomirova, Laima, Tischkowitz, Marc, Tollenaar, Robert A. E. M., Tomlinson, Ian, Torres, Diana, Truong, Thérèse, Tucker, Kathy, Tung, Nadine, Tworoger, Shelley S., van der Ouweland, Ans M. W., Van Maerken, Tom, van Rensburg, Elizabeth J., Varon-Mateeva, Raymonda, Viel, Alessandra, Wang, Qin, Wappenschmidt, Barbara, Weitzel, Jeffrey N., Wentzensen, Nicolas, Whittermore, Alice S., Winqvist, Robert, Woo, Yin Ling, Wu, Anna, Yoon, Sook-Yee, Zheng, Wei, Öfverholm, Anna +252 morecore +1 more sourceInactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions
Nature Communications, 2019 OPCML is a tumour suppressor gene that is epigenetically silenced in ovarian cancer and is somatically mutated in various cancers. Here, the authors solve the X-ray crystal structure of OPCML and model clinically relevant mutations that could contribute ...James R. Birtley, Mohammad Alomary, Elisa Zanini, Jane Antony, Zachary Maben, Grant C. Weaver, Claudia Von Arx, Manuela Mura, Aline T. Marinho, Haonan Lu, Eloise V. N. Morecroft, Evdoxia Karali, Naomi E. Chayen, Edward W. Tate, Mollie Jurewicz, Lawrence J. Stern, Chiara Recchi, Hani Gabra +17 moredoaj +1 more sourceLINE-1 ORF1p as a candidate biomarker in high grade serous ovarian carcinoma
Scientific Reports, 2023 Long interspersed element 1 (LINE-1) open reading frame 1 protein (ORF1p) expression is a common feature of many cancer types, including high-grade serous ovarian carcinoma (HGSOC).Sho Sato, Michael Gillette, Pamela R. de Santiago, Eric Kuhn, Michael Burgess, Kristen Doucette, Yi Feng, Carlos Mendez-Dorantes, Paul J. Ippoliti, Sara Hobday, Marilyn A. Mitchell, Kai Doberstein, Stefan M. Gysler, Michelle S. Hirsch, Lauren Schwartz, Michael J. Birrer, Steven J. Skates, Kathleen H. Burns, Steven A. Carr, Ronny Drapkin +19 moredoaj +1 more sourceAutophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors. [PDF]
, 2020 Autophagy, particularly with BECN1, has paradoxically been highlighted as tumor promoting in Ras-driven cancers, but potentially tumor suppressing in breast and ovarian cancers.Axelrod, Joshua, Bapat, Jaidev, Delaney, Joe R, DeStefano, John W, Haghighiabyaneh, Mina, Harismendy, Olivier, Jones, Christian M, La Spada, Albert R, Ortell, Katherine K, Patel, Chandni B, Ramos-Zapatero, Maria, Schlaepfer, David D, Stupack, Dwayne G, Tancioni, Isabelle, Tanios, Ralph +14 morecore In Vitro Chemosensitivity Using the Histoculture Drug Response Assay in Human Epithelial Ovarian Cancer [PDF]
, 2012 The choice of chemotherapeutic drugs to treat patients with epithelial ovarian cancer has not depended on individual patient characteristics. We have investigated the correlation between in vitro chemosensitivity, as determined by the histoculture drug ...Kim, Dae-Yeon, Kim, Jong-Hyeok, Kim, Moon-Bo, Kim, Yong-Man, Kim, Young-Tak, Lee, Shin-Wha, Nam, Joo-Hyun +6 morecore +1 more source
