Results 71 to 80 of about 5,217,497 (361)

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

Advancing Research Alongside Patient Partners: Next-Generation Best Practices for Effective Collaboration in Health Research

open access: yesCurrent Oncology
Ovarian Cancer Canada’s Patient Partners in Research (PPiR) is a national volunteer-based program that trains and connects individuals with lived ovarian cancer (OC) experience to diverse research opportunities, to maximize the clinical relevance and ...
Ally C. Farrell   +4 more
doaj   +1 more source

Control of triple-negative breast cancer using ex vivo self-enriched, costimulated NKG2D CAR T cells

open access: yesJournal of Hematology & Oncology, 2018
Background Triple-negative breast cancer (TNBC) is an aggressive disease that currently lacks effective targeted therapy. NKG2D ligands (NKG2DLs) are expressed on various tumor types and immunosuppressive cells within tumor microenvironments, providing ...
Yali Han   +3 more
doaj   +1 more source

Epidemiology of ovarian cancer: a review

open access: yesCancer Biology and Medicine, 2017
Ovarian cancer (OC) is the seventh most commonly diagnosed cancer among women in the world and the tenth most common in China. Epithelial OC is the most predominant pathologic subtype, with five major histotypes that differ in origination, pathogenesis ...
B. Reid, J. Permuth, T. Sellers
semanticscholar   +1 more source

The untapped potential of ascites in ovarian cancer research and treatment

open access: yesBritish Journal of Cancer, 2020
The build-up of fluid in the peritoneal cavity—ascites—is a hallmark of ovarian cancer, the most lethal of all gynaecological malignancies. This remarkable fluid, which contains a variety of cellular and acellular components, is known to contribute to ...
C. Ford   +3 more
semanticscholar   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Impact of metabolic syndrome on the risk of endometrial cancer and the role of lifestyle in prevention

open access: yesBiomolecules & Biomedicine, 2022
Endometrial cancer is the second gynecological cancer with the highest global incidence. Among many associated risk factors, metabolic syndrome is an important and preventable one.
Alejandra Rocío Pérez-Martín   +8 more
doaj   +1 more source

Inflammation is a key contributor to ovarian cancer cell seeding. [PDF]

open access: yes, 2018
The incidence of ovarian cancer dramatically increases in early menopause but the factors contributing to cancer onset are unclear. Most ovarian cancers originate in the fallopian tube with subsequent implantation of malignant cells into the ovary ...
Jia, Dongyu   +3 more
core   +1 more source

Epigenetics in ovarian cancer: premise, properties, and perspectives. [PDF]

open access: yes, 2018
Malignant ovarian tumors bear the highest mortality rate among all gynecological cancers. Both late tumor diagnosis and tolerance to available chemical therapy increase patient mortality.
Huang, Shuang   +16 more
core   +2 more sources

Adipocyte-Induced FABP4 Expression in Ovarian Cancer Cells Promotes Metastasis and Mediates Carboplatin Resistance

open access: yesCancer Research, 2020
Ovarian cancer metastatic progression can be restricted by targeting a critical regulator of lipid responses, FABP4. Adipocytes are critical for ovarian cancer cells to home to the omentum, but the metabolic changes initiated by this interaction are ...
A. Mukherjee   +8 more
semanticscholar   +1 more source

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