Results 171 to 180 of about 272,037 (262)

HER3 and FOLR1 Expression as Actionable Targets in High-Grade Serous Ovarian Carcinoma: Prognostic and Therapeutic Implications. [PDF]

Medicina (Kaunas)
Kalkan NO, Yuceer RO, Kaya S, Dogru N, Yıldırım A.   +4 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Keratin 5 marks cancer-propagating cells sustained by an osteopontin-producing niche in high-grade serous ovarian carcinoma. [PDF]

Cancer Heterog Plast
Bidarimath M, Ralston CQ, Bidarimath N, Rose IM, Colina D, Schmoeckel E, Godwin AK, Mayr D, Ellenson LH, Flesken-Nikitin A, Nikitin AY.   +10 more
europepmc   +1 more source

Recent advances and clinical applications of 3D printing for female reproductive organ regeneration and gynecological disease

Interdisciplinary Medicine, EarlyView.
This comprehensive review highlights the transformative role of 3D printing and bioprinting technologies in the regeneration of female reproductive organs and the treatment of gynecological diseases. Unlike previous overviews that focus narrowly on isolated applications, this work provides an integrative analysis of recent clinical and preclinical ...
Chan Hum Park, In‐Sun Hong
wiley   +1 more source

High-Grade Serous Ovarian Carcinoma in the Genomics Era: Current Applications, Challenges and Future Directions. [PDF]

Int J Mol Sci
Lewis ME, Caricato C, Roberts HL, Ganesan S, Seksaf NA, Maniati E, Sideris M.   +6 more
europepmc   +1 more source

Molecular Functions and Drug Prediction of MMP1 and TGFBR2 in Nasopharyngeal Carcinoma

Journal of Clinical Laboratory Analysis, EarlyView.
MMP1 and TGFBR2 were validated by machine learning and external datasets as the candidate genes. Dexamethasone showed strong binding affinity to MMP1 (−7.72 kcal/mol) and TGFBR2 (−7.27 kcal/mol) in docking studies. Knockdown of MMP1 repressed the malignant phenotypes of NPC cells.
Feng Wang, Binbin Ge, Ming Li, Xiaochun Xia, Fuming Zhang, Pengqin Xu   +5 more
wiley   +1 more source

Validation of QuANTUM-derived tumor cell fraction for molecular testing in high-grade serous tubo-ovarian carcinoma. [PDF]

NPJ Precis Oncol
Alviano AM, Pagni F, Seminati D, Casati G, Jaconi M, Fruscio R, De Leo A, Maloberti T, L'Imperio V, De Biase D, Cazzaniga G.   +10 more
europepmc   +1 more source

Clinical Rationale of Dual‐Parameter Tumor Markers Reporting Without Reliance on Normal Reference Ranges

Journal of Clinical Laboratory Analysis, EarlyView.
We recommend the current practice of tumor marker reporting to upgrade to two‐figure format to include a specific growth rate in parentheses. This can be of great clinical importance, especially in the subnormal range. ABSTRACT Introduction This review offers clinicians a novel view of tumor markers (TM).
Jurate Civinskaite, Daiva Gudaviciene, Gintaras Zaleskis, Aleksandras Petrauskas, Dainius Characiejus, Tatjana Ivaskiene   +5 more
wiley   +1 more source

Deceptive clinical course of mucinous ovarian carcinoma mimicking pelvic abscess in a postmenopausal woman: An exceptional case report. [PDF]

Oncoscience
Jarathi A, Geddada S, Ramalingam C, Kumar N, Devalla A, Pitambra A, Rath A, Kari ND, Janke UR, Reddy BS, Kondeti AK.   +10 more
europepmc   +1 more source