Results 191 to 200 of about 281,298 (260)

MALDI-MSI Profiling of Effusion Cytology Cell Blocks Distinguishes High-Grade Serous Ovarian Carcinoma from Benign Effusions. [PDF]

Cancers (Basel)
Casadonte R, Friemel A, Klein O, Kriegsmann SM, Hansen T, Kriegsmann J.   +5 more
europepmc   +1 more source

Clinical Translation of Patient‐Derived Organoids: Perspectives for Personalized Therapy in Cancer

International Journal of Cancer, EarlyView.
ABSTRACT Patient‐derived organoids (PDO) are accelerating precision medicine. These biological platforms allow for the autologous in vitro expansion of material from cancer patients in a considerably short period of time. These three‐dimensional models can faithfully recapitulate aspects of tissue heterogeneity, architecture, and relevant cellular ...
Haiyan Yue, Daniele Carchidi, Philipp Schmucker, Roland Seiler, Bernhard Kiss, Catarina Macedo‐Silva, Marianna Kruithof‐de Julio   +6 more
wiley   +1 more source

Differences in the clinical significance of CA125 for detecting progression among histological subtypes of epithelial ovarian carcinoma. [PDF]

Mol Clin Oncol
Kato K, Miyamoto M, Nishimura S, Tanabe R, Ito T, Kishimoto N, Suminokura J, Otsuka Y, Hada T, Soyama H, Omatsu K, Hamada Y, Takano M.   +12 more
europepmc   +1 more source

Impact of Single‐Cell RNA Reference Selection for the Deconvolution of Breast Cancer Spatial Transcriptomics Datasets

International Journal of Cancer, EarlyView.
ABSTRACT Spot‐based spatial transcriptomics (ST) allows for unbiased gene expression analysis within tissue architecture, overcoming the limitations of single‐cell RNA sequencing (scRNA‐seq) by preserving spatial context. However, the high spatial resolution in ST leads to cellular heterogeneity within spots, requiring computational deconvolution to ...
Stefan Altendorfer, Scott J. Walker, Carsten O. Daub   +2 more
wiley   +1 more source

First-In-Human Trial of Encapsulated Cells Constitutively Expressing Localized IL2 in Patients with High-Grade Serous Ovarian Carcinoma. [PDF]

Clin Cancer Res
Clark HD, Aghlara-Fotovat S, Schladenhauffen J, Debonis J, Amador-Molina JC, Nash A, Jain M, Newman R, Jansen L, Andreas K, Rangel K, Sims TT, Fellman B, Dansky Ullmann C, Yeku O, Bregar AJ, Blakely AM, Mathews C, Igoshin OA, Haymaker C, Oberholzer J, Rios P, Lopez D, Nasir H, Joshi I, Chakrabarti R, Veiseh O, Jazaeri AA, Westin SN.   +28 more
europepmc   +1 more source

Impact of ovarian preservation on survival for premenopausal women with early‐stage endometrial carcinoma: A systematic review and meta‐analysis

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Up to 14% of women with early‐stage endometrial carcinoma (EEC) are diagnosed before menopause. Although ovarian preservation (OP) within surgical staging might avoid surgical menopause, its rate remains low in clinical practice, probably because the impact of OP on survival outcomes is unclear.
Antonio Raffone, Diego Raimondo, Daniele Neola, Manuela Maletta, Marisol Doglioli, Antonio Travaglino, Carlo Ronsini, Maria Giovanna Vastarella, Stefano Ferla, Francesco Cosentino, Pasquale De Franciscis, Renato Seracchioli, Luigi Cobellis   +12 more
wiley   +1 more source

Integrative In Silico mRNA-miRNA Profiling of mTOR Pathway Dysregulation in High-Grade Serous Ovarian Carcinoma. [PDF]

Cancers (Basel)
Hablase R, Sisu C, Karteris E, Chatterjee J.   +3 more
europepmc   +1 more source

Retrospective analysis of outcome after endometrial ablation with the NovaSure device: A German single‐center experience

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Evaluation of retrospective outcomes of NovaSure treatment in patients with abnormal uterine bleeding, including safety and cost‐effectiveness, and risk factors related to therapeutic outcomes. Subgroup analysis was conducted for patients who underwent concomitant surgical procedures, required subsequent interventions, and were ...
Oliver M. Schleicher, Felix Heindl, Julia Gocke, Katharina Keller, Lothar Häberle, Alaa Hamzeh, Christian Matek, Matthias W. Beckmann, Julius Emons   +8 more
wiley   +1 more source

TROP2-targeting antibody-drug conjugates in breast cancer and ovarian carcinoma: therapeutic advances and resistance mechanisms. [PDF]

Cancer Drug Resist
Eroles P, Dawid de Vera MT, Lago V.
europepmc   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source