Results 21 to 30 of about 10,005,454 (320)

Polycystic Ovarian Disease

open access: yesCleveland Clinic Journal of Medicine, 1985
Polycystic ovarian disease represents a poorly defined spectrum of clinical disorders having oligo-ovulation or anovulation as a common feature. There is no single, universally accepted biochemical or clinical definition. Clinical findings usually include anovulation resulting in irregular uterine bleeding and infertility, androgen excess resulting in ...
Z. N. Zakov, M. M. Quigley
  +6 more sources

RUNX1-Regulated Signaling Pathways in Ovarian Cancer

open access: yesBiomedicines, 2023
Ovarian cancer is the leading cause of gynecological death worldwide, and its poor prognosis and high mortality seriously affect the life of ovarian cancer patients.
Yuanzhi Chen, Yingying He, Shubai Liu
doaj   +1 more source

The role of the microbiome in ovarian cancer: mechanistic insights into oncobiosis and to bacterial metabolite signaling

open access: yesMolecular Medicine, 2021
Ovarian cancer is characterized by dysbiosis, referred to as oncobiosis in neoplastic diseases. In ovarian cancer, oncobiosis was identified in numerous compartments, including the tumor tissue itself, the upper and lower female genital tract, serum ...
A. Sipos   +7 more
semanticscholar   +1 more source

Anti-tumorigenic and Platinum-Sensitizing Effects of Apolipoprotein A1 and Apolipoprotein A1 Mimetic Peptides in Ovarian Cancer

open access: yesFrontiers in Pharmacology, 2019
Objective: Apolipoprotein A1 (ApoA1) is remarkably decreased in serum and ovarian tissues of ovarian cancer patients. ApoA1 and ApoA1 mimetic peptides can sequestrate pro-inflammatory phospholipids, some of which are known to activate a variety of ...
Aline T. Marinho   +8 more
doaj   +1 more source

Low 25-OH vitamin D levels at time of diagnosis and recurrence of ovarian cancer. [PDF]

open access: yes, 2015
The objective of this study was to evaluate the correlation between 25-OH vitamin D and ovarian cancer as a diagnostic marker or recurrence disease marker.
Anastasi, Emanuela   +6 more
core   +1 more source

Human epididymis protein 4 (HE4) in benign and malignant diseases [PDF]

open access: yes, 2012
Background: Human epididymis protein 4 (HE4) is described as a useful new biomarker in ovarian cancer. As HE4 is neither tumor nor organ specific, we intensively investigated the occurrence of this protein in female and male patients with various benign ...
Anastasi   +39 more
core   +1 more source

PREMATURE OVARIAN INSUFFICIENCY IN SYSTEMIC SCLEROSIS

open access: yesAnti-Aging Eastern Europe, 2022
The early onset of ovarian aging results in decreased ovarian reserve and premature ovarian insufficiency (POI), leading to infertility and early menopause. POI is associated with systemic autoimmune diseases.
Neslihan Gokcen
doaj   +1 more source

HE4 in the differential diagnosis of ovarian masses [PDF]

open access: yes, 2015
Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela   +5 more
core   +1 more source

Transplantation of human umbilical cord mesenchymal stem cells to treat premature ovarian failure

open access: yesStem cell research & therapeutics, 2021
As one of the problems and diseases for women before 40 years, premature ovarian failure (POF) could be characterized by amenorrhea, low estrogen levels, infertility, high gonadotropin levels, and lack of mature follicles.
Oldouz Shareghi-oskoue   +2 more
semanticscholar   +1 more source

Screening for Gynecologic Conditions With Pelvic Examination US Preventive Services Task Force Recommendation Statement [PDF]

open access: yes, 2017
IMPORTANCE Many conditions that can affect women\u27s health are often evaluated through pelvic examination. Although the pelvic examination is a common part of the physical examination, it is unclear whether performing screening pelvic examinations in ...
Barry, Michael J   +19 more
core   +2 more sources

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