HE4 in the differential diagnosis of ovarian masses [PDF]
, 2015 Ovarian masses, a common finding among pre- and post-menopausal women, can be benign or malignant. Ovarian cancer is the leading cause of death from gynecologic malignancy among women living in industrialized countries.
ANASTASI, Emanuela +5 more
core +1 more source
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]
, 2020 [Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida +6 more
core +1 more source
Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus [PDF]
, 2017 Mitochondrial dysfunction is a common hallmark in aging. In the female, reproductive senescence is characterized by loss of ovarian hormones, many of whose neuroprotective effects converge upon mitochondria.
Alvarez, Silvia +7 more
core +2 more sources
Screening for Gynecologic Conditions With Pelvic Examination US Preventive Services Task Force Recommendation Statement [PDF]
, 2017 IMPORTANCE Many conditions that can affect women\u27s health are often evaluated through pelvic examination. Although the pelvic examination is a common part of the physical examination, it is unclear whether performing screening pelvic examinations in ...
Barry, Michael J +19 more
core +2 more sources
Frontiers in Physiology, 2020 In mammals, developing ovarian follicles transform from primordial follicles to primary follicles, secondary follicles, and mature follicles, accompanied by changes in follicular secretory functions.
Hong Zhang +4 more
doaj +1 more source
CA 125 Elevation: A Descriptive Etiological Study [PDF]
National Journal of Laboratory Medicine, 2016 Introduction: CA 125 (Cancer/Carbohydrate antigen 125) is a surface antigen expressed mostly by the ovarian cancer cells. Hence, it is widely used as a tumour marker for detection and monitoring the progression of such cancers.
Shaheena Appan Parambath +6 more
doaj +1 more source
The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [PDF]
, 2011 Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy.
Burges, Alexander +9 more
core +1 more source
The Role of Three Plasma Proteins in the Diagnosis of Ovarian Tumors [PDF]
Journal of Biomedical & Clinical Research, 2022 Ovarian cancer is not common, but it is still the fifth leading cause of death from malignant diseases among women worldwide. More than 200,000 women are diagnosed with ovarian cancer each year globally.
Valeria Racheva +3 more
doaj +3 more sources
Dual role for the unfolded protein response in the ovary: adaption and apoptosis
Protein & Cell, 2016 The endoplasmic reticulum (ER) is the principal organelle responsible for several specific cellular functions including synthesis and folding of secretory or membrane proteins, lipid metabolism, and Ca2+ storage.
Ning Huang, Yang Yu, Jie Qiao
doaj +1 more source
Epidemiology and Characteristics of Extra-ovarian Conditions Mimicking Ovarian Cancer: A 4-Year Assay Among Iranian Women [PDF]
International Journal of Travel Medicine and Global Health, 2018 Introduction: Involving approximately 4% of malignancies in women, ovarian cancer remains one of the most fatal cancers. However, it is important to consider conditions which are not primary ovarian diseases, but mimic their behaviors.
Seyedeh Razieh Hashemi +4 more
doaj +1 more source