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Epithelial ovarian cancer (EOC) is the sixth most common cause of cancer deaths in women because the diagnosis occurs mostly when the disease is in its late-stage. Current diagnostic methods of EOC show only a moderate sensitivity, especially at an early-
K. Biskup +4 more
semanticscholar +1 more source
CA 125 Elevation: A Descriptive Etiological Study [PDF]
Introduction: CA 125 (Cancer/Carbohydrate antigen 125) is a surface antigen expressed mostly by the ovarian cancer cells. Hence, it is widely used as a tumour marker for detection and monitoring the progression of such cancers.
Shaheena Appan Parambath +6 more
doaj +1 more source
The Role of Three Plasma Proteins in the Diagnosis of Ovarian Tumors [PDF]
Ovarian cancer is not common, but it is still the fifth leading cause of death from malignant diseases among women worldwide. More than 200,000 women are diagnosed with ovarian cancer each year globally.
Valeria Racheva +3 more
doaj +3 more sources
Dual role for the unfolded protein response in the ovary: adaption and apoptosis
The endoplasmic reticulum (ER) is the principal organelle responsible for several specific cellular functions including synthesis and folding of secretory or membrane proteins, lipid metabolism, and Ca2+ storage.
Ning Huang, Yang Yu, Jie Qiao
doaj +1 more source
Epidemiology and Characteristics of Extra-ovarian Conditions Mimicking Ovarian Cancer: A 4-Year Assay Among Iranian Women [PDF]
Introduction: Involving approximately 4% of malignancies in women, ovarian cancer remains one of the most fatal cancers. However, it is important to consider conditions which are not primary ovarian diseases, but mimic their behaviors.
Seyedeh Razieh Hashemi +4 more
doaj +1 more source
Hormone deprivation alters mitochondrial function and lipid profile in the hippocampus [PDF]
Mitochondrial dysfunction is a common hallmark in aging. In the female, reproductive senescence is characterized by loss of ovarian hormones, many of whose neuroprotective effects converge upon mitochondria.
Alvarez, Silvia +7 more
core +2 more sources
Dear Sir, Crohn's disease is a chronic inflammatory disorder that may involve any portion of the gastrointestinal tract. Predominant symptoms include abdominal pain, diarrhea and weight loss. The hallmark of Crohn's disease is bowel inflammation with fistula or stricture formation.
A. Ouakaa-Kchaou +6 more
openaire +1 more source
The objectives of this study were 1) to determine the effects of adding a CIDR to the Ovsynch protocol on plasma concentrations of estradiol-17β and progesterone and conception in dairy cows with cystic ovarian diseases and 2) to examine associations ...
N. Kawate +5 more
semanticscholar +1 more source
The diagnostic accuracy of two human epididymis protein 4 (HE4) testing systems in combination with CA125 in the differential diagnosis of ovarian masses [PDF]
Background: Cancer antigen 125 (CA125) is the best known single tumor marker for ovarian cancer (OC). We investigated whether the additional information of the human epididymis protein 4 (HE4) improves diagnostic accuracy.
Burges, Alexander +9 more
core +1 more source
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use [PDF]
[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor.
Barreiro-Alonso, Aida +6 more
core +1 more source

