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Dear Sir, Crohn's disease is a chronic inflammatory disorder that may involve any portion of the gastrointestinal tract. Predominant symptoms include abdominal pain, diarrhea and weight loss. The hallmark of Crohn's disease is bowel inflammation with fistula or stricture formation.
A. Ouakaa-Kchaou +6 more
openaire +1 more source
Ovarian Fibrosis: A Phenomenon of Concern
Objective: Ovarian fibrosis is characterized by excessive proliferation of ovarian fibroblasts and deposition of extracellular matrix (ECM) and it is one of the principal reasons for ovarian dysfunction.
Feng Zhou, Li-Bing Shi, Song-Ying Zhang
doaj +1 more source
The Role of m6A on Female Reproduction and Fertility: From Gonad Development to Ovarian Aging
The growth and maturation of oocyte is accompanied by the accumulation of abundant RNAs and posttranscriptional regulation. N6-methyladenosine (m6A) is the most prevalent epigenetic modification in mRNA, and precisely regulates the RNA metabolism as well
Xiaoyan Sun +3 more
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Fertility preservation in gynaecologic cancers [PDF]
Due to substantial improvement in the diagnosis and treatment of gynaecologic cancers, a better understanding of patient care needs to be revised. We reviewed the literature related to fertility preservation strategies in gynaecological cancer and ...
De Felice, Francesca +9 more
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The role of peroxiredoxins in cancer [PDF]
Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite.
CAPALBO, CARLO +4 more
core +1 more source
Female germline stem cells: aging and anti-aging
The delay of ovarian aging and the fertility preservation of cancer patients are the eternal themes in the field of reproductive medicine. Acting as the pacemaker of female physiological aging, ovary is also considered as the principle player of cancer ...
Wenli Hong +9 more
doaj +1 more source
Advances in the design and development of oncolytic measles viruses. [PDF]
A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian +2 more
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Declining fertility due to ovarian dysfunction is a critical concern for population sustainability. Acupuncture shows potential for ovarian functional restoration, primarily mediated through its neuromodulatory effects on the hypothalamic-pituitary ...
Yu Bu +7 more
doaj +1 more source
TGF-β Signaling in the Pathophysiology of the Ovary: A Double-Edged Regulator
The Transforming Growth Factor-β (TGF-β) superfamily comprises highly conserved cytokines that orchestrate key cellular functions, including proliferation, differentiation, and apoptosis. Within the ovary, TGF-β family members serve as pivotal regulators
Nicole Bertani +11 more
doaj +1 more source
Aim: Diminished ovarian reserve can be characterized by poor response to ovulation and low number of eggs. The risk factors include endometriosis, receiving cancer treatment, luteal phase deficiency and gynecologic surgery.
Xiaolong Shi +4 more
doaj +1 more source

