Results 61 to 70 of about 10,005,454 (320)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Vaccines in Current Culture: The HPV Vaccine Controversy [PDF]
, 2020 The use of vaccinations has drastically decreased mortality and morbidity rates related to infectious disease and has become an intrinsic part of modern health care.
Johnston, Alyssa
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Frontiers in Veterinary ScienceIntroductionOptimizing the management of dairy cattle reproduction can reduce postpartum ovarian disease in high-yielding dairy cows and thus enhance ranch economic benefit.
Ziyuan Li +17 more
doaj +1 more source
The Professional Medical Journal, 2006 Introduction: Poly Cystic Ovarian Disease (PCOD) is probably one of the most commonendocrinological disorders amongst the women during their reproductive years. Using USG criteria only 20-33% ofapparently healthy women in childbearing period, have been found to have PCOD in population study.
SHAHID IRSHAD RAO +2 more
openaire +2 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
MicroRNAs and Recent Insights into Pediatric Ovarian Cancers
Frontiers in Oncology, 2013 Ovarian cancer is the most common pediatric gynecologic malignancy. When diag-nosed in children, ovarian cancers present unique challenges that differ dramatically from those faced by adults. Here, we review the spectrum of ovarian cancers found in young
Jessica Anne Crawford +6 more
doaj +1 more source
INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA
Sabiad, 2022 Objective: The most common cancers in women are breast, thyroid, colorectal, uterine corpus, lung and ovarian cancer. Ovarian cancer causes more than 150,000 deaths annually worldwide. The fact that this cancer manifests itself in the late stage and is a
Yasemin Gider +9 more
doaj +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Cancer biomarkers, and novel techniques for detection [PDF]
, 2017 Technologies for early detection of tumors is critical for better therapy outcome and overall change in cancer survival. These assays must be capable of detecting tumors at early stages in order to prevent metastasis of the tumor and help reduce ...
Jamal, Tameem
core