The Mare Model to Study the Effects of Ovarian Dynamics on Preantral Follicle Features. [PDF]
PLoS ONE, 2016 Ovarian tissue collected by biopsy procedures allows the performance of many studies with clinical applications in the field of female fertility preservation.
Kele A Alves +7 more
doaj +6 more sources
Species-specific differences in follicular antral sizes result from diffusion-based limitations on the thickness of the granulosa cell layer [PDF]
, 2013 The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte. Here we show that the different follicular sizes can be explained with diffusion-based limitations on the thickness of the ...
Bächler, M. +3 more
arxiv +3 more sources
Progesterone Signaling and Mammalian Ovarian Follicle Growth Mediated by Progesterone Receptor Membrane Component Family Members [PDF]
Cells, 2022 How progesterone influences ovarian follicle growth is a difficult question to answer because ovarian cells synthesize progesterone and express not only the classic nuclear progesterone receptor but also members of the progestin and adipoQ receptor ...
John J. Peluso
doaj +2 more sources
Bridging Time Scales in Cellular Decision Making with a Stochastic Bistable Switch [PDF]
arXiv, 2010 Cellular transformations which involve a significant phenotypical change of the cell's state use bistable biochemical switches as underlying decision systems. In this work, we aim at linking cellular decisions taking place on a time scale of years to decades with the biochemical dynamics in signal transduction and gene regulation, occuring on a time ...
A Gougeon +44 more
arxiv +7 more sources
Protein Palmitoylation in Bovine Ovarian Follicle. [PDF]
Int J Mol Sci, 2021 Protein palmitoylation is a reversible post-translational modification by fatty acids (FA), mainly a palmitate (C16:0). Palmitoylation allows protein shuttling between the plasma membrane and cytosol to regulate protein stability, sorting and signaling activity and its deficiency leads to diseases.
Uzbekova S +8 more
europepmc +7 more sources
Multi-scale modeling of follicular ovulation as a reachability problem [PDF]
Multiscale Modeling & Simulation 6, 3 (2007) 895--912, 2006 During each ovarian cycle, only a definite number of follicles ovulate, while the others undergo a degeneration process called atresia. We have designed a multi-scale mathematical model where ovulation and atresia result from a hormonal controlled selection process.
Frederique Clément +4 more
arxiv +7 more sources
CPEB3 deficiency in mice affect ovarian follicle development and causes premature ovarian insufficiency [PDF]
Cell Death and Disease, 2021 Premature ovarian insufficiency (POI) is a heterogeneous and multifactorial disorder. In recent years, there has been an increasing interest in research on the pathogenesis and treatment of POI, owing to the implementation of the second-child policy in ...
Fang E. +13 more
doaj +2 more sources
Amburana cearensis leaf extract protects against cisplatin-induced ovarian damage through regulation of p-PTEN and p-Akt proteins in mice [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): To evaluate the effects of Amburana cearensis leaf extract against cisplatin-induced ovarian toxicity in mice and involvement of p-PTEN and p-Akt proteins. Materials and Methods: A.
Bruna B. Gouveia +10 more
doaj +1 more source
Cells, 2022 Our previous study demonstrated that ovarian wild-type P53-induced phosphatase 1 (WIP1) expression decreased with age. We hypothesized that WIP1 activity was related to ovarian aging. The role of WIP1 in regulating ovarian aging and its mechanisms remain
Su Zhou +9 more
doaj +1 more source
Does AMH Reflect Follicle Number Similarly in Women with and without PCOS? [PDF]
PLoS ONE, 2016 Increased Anti-Mullerian Hormone in polycystic ovary syndrome, may be due to overactive follicles rather than reflect antral follicle count.Does Anti-Mullerian Hormone reflect antral follicle count similarly in women with or without polycystic ovary ...
Sverre C Christiansen +3 more
doaj +1 more source