Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin. [PDF]
While mutations in the fragile X mental retardation-1 (FMR1) gene are associated with varying reproductive outcomes in females, the effects of a complete lack of FMR1 expression are not known.
Ascano, M+5 more
core +2 more sources
TMCO1 is essential for ovarian follicle development by regulating ER Ca2+ store of granulosa cells
TMCO1 (transmembrane and coiled-coil domains 1) is an endoplasmic reticulum (ER) transmembrane protein that actively prevents Ca2+ stores from overfilling. To characterize its physiological function(s), we generated Tmco1−/− knockout (KO) mice.
Zhongshuai Sun+12 more
semanticscholar +1 more source
Is there a relationship between ovarian reserve and blood groups in infertile patients?
Objective: Evaluation of ovarian reserve in infertile patients had become an important concept in assisted reproductive techniques (ART) success work-up. Recent studies reported an association between blood type and ovarian reserve. Therefore, the aim of
Ozgur Kan+6 more
doaj +1 more source
Computer-Generated Ovaries to Assist Follicle Counting Experiments [PDF]
Precise estimation of the number of follicles in ovaries is of key importance in the field of reproductive biology, both from a developmental point of view, where follicle numbers are determined at specific time points, as well as from a therapeutic ...
A Gougeon+18 more
core +3 more sources
Background The maturation of the female germ cell, the oocyte, requires the synthesis and storing of all the necessary metabolites to support multiple divisions after fertilization.
Beatriz Peñalver Bernabé+7 more
doaj +1 more source
Female reproductive decline is determined by remaining ovarian reserve and age. [PDF]
The early decline and loss of female fertility in humans and other species represents an evolutionary paradox. Despite being born with a vast stock of oocytes, females encounter an exhaustion of ovarian reserve and sterility half way through their ...
Pawel Wilkosz+3 more
doaj +1 more source
The objectives of this study were (1) to investigate the distribution of large (≥10 mm) follicle numbers during the estrous cycle and (2) to compare the timing of the estrus expression period after the ovarian examination between cows with one large ...
Ryotaro Miura+9 more
doaj +1 more source
Follicular and endocrine dose responses according to anti-Müllerian hormone levels in IVF patients treated with a novel human recombinant FSH (FE 999049) [PDF]
Objective: To study the association between serum anti-Mullerian hormone (AMH) levels and follicular development and endocrine responses induced by increasing doses (5.2-12.1 mu g/day) of a novel recombinant human FSH (rhFSH, FE 999049) in patients ...
Andersen, Anders Nyboe+9 more
core +2 more sources
Lipid Identification and Transcriptional Analysis of Controlling Enzymes in Bovine Ovarian Follicle
Ovarian follicle provides a favorable environment for enclosed oocytes, which acquire their competence in supporting embryo development in tight communications with somatic follicular cells and follicular fluid (FF). Although steroidogenesis in theca (TH)
P. Bertevello+12 more
semanticscholar +1 more source
Ovarian reserve in patients who have undergone endometriosis surgery [PDF]
Background/Aim. Endometriosis is a gynaecological disorder characterized by the presence of endometrial tissue outside the uterine cavity. The aim of this paper was to determine the effect of laparoscopic cystotomy and cystectomy on ovarian function, as ...
Džatić-Smiljković Olivera+5 more
doaj +1 more source