Results 91 to 100 of about 5,436,969 (234)

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Association Between Blood Transfusion for Postpartum Haemorrhage and the Risk of Premature Ovarian Failure: A Nationwide Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To investigate the association between postpartum haemorrhage (PPH) severity and the subsequent risk of premature ovarian failure (POF), with blood transfusion used as a marker of severe PPH: Design Nationwide population‐based retrospective cohort study. Setting Korean National Health Insurance Service (KNHIS) database.
Min‐A Kim, Ju Hyeong Son, Hyun‐Joo Seol, Min‐Jeong Oh, Geum Joon Cho, Young‐Han Kim   +5 more
wiley   +1 more source

Ovarian Granulosa Cell Genomics in PCOS .zip

, 2023
To investigate gene expression in ovarian granulosa cells by using high-throughput gene sequencing and to investigate pathogenesis in phlegm wet polycystic ovary syndrome (PCOS) patients using functional and pathway analyses. 
shuai zhao (14793550)
core   +1 more source

Inhibin βB Mediates Oligotrophic Adaptation via Regulating Muscle Satellite Cell Proliferation and Differentiation in Schizopygopsis younghusbandi

Integrative Zoology, EarlyView.
① Nutrient deficiency upregulates inhibin βB, activating SMAD signaling to promote p21. Increased p21 inhibits mcm2/mcm4/mcm5 and cyclin E2, inducing G1‐phase arrest, slowing growth, and reducing energy consumption. ② Inhibin βB also upregulates pdgf‐c, which induces α‐SMA, leading to muscle satellite cell fibrosis.
Weiqiang Li, He Gao, Chaowei Zhou, Luo Lei, Junting Li, Chao Ma, Zitu Ma, Mengwei Yao, Kexin Ma, Yunpeng Xiang, Yan Zhou, Yongrui Lu, Da Ji, Minghong Wei, Luohao Xu, Zhaofang Han, Haiping Liu   +16 more
wiley   +1 more source

Lifestyle Management in Menopause: A Systematic Review of Women With Premature Ovarian Insufficiency

Clinical Endocrinology, EarlyView.
ABSTRACT Objective Premature ovarian insufficiency (POI), the loss of ovarian function before age 40, increases the risk of cardiovascular disease, low bone mineral density, dementia and psychological distress. Lifestyle interventions reduce chronic disease risk in other populations and, with hormone therapy, may improve health outcomes in POI.
Ladan Yeganeh, Nathalie Vermeulen, Carolyn Ee, Helena Teede, Amanda J. Vincent   +4 more
wiley   +1 more source

METTL3 prevents granulosa cells mitophagy by regulating YTHDF2-mediated BNIP3 mRNA degradation due to arsenic exposure

Ecotoxicology and Environmental Safety
The ovary is an important reproductive and endocrine organ for the continuation of the species and the homeostasis of the body's internal environment. Arsenic exposure is a global public health problem.
Tuo Zhang, Jin Niu, Tianhe Ren, Huan Lin, Meina He, Zhiyi Sheng, Yuntong Tong, Bangming Jin, Yingmin Wu, Jigang Pan, Ziwen Xiao, Bing Guo, Zhengrong Wang, Tengxiang Chen, Wei Pan   +14 more
doaj   +1 more source

The human ovarian granulosa cell: a stereological approach.

Journal of anatomy, 1996
The human ovarian granulosa cell is perhaps the most widely studied endocrine cell, but little quantitative structural information exists for this cell. In the present study new and traditional stereological probes have been employed to provide quantitative structural information on these functionally important cells. Granulosa cells were obtained from
O, WS, Dhar, A, Dockery, P, Turner, K, Lenton, EA, Cooke, ID   +5 more
openaire   +2 more sources

Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling

Reproductive Biology and Endocrinology, 2017
Background Transforming growth factor beta (TGFB) superfamily signaling is implicated in the development of sex cord-stromal tumors, a category of poorly defined gonadal tumors.
Yang Gao, Xin Fang, David F. Vincent, David W. Threadgill, Laurent Bartholin, Qinglei Li   +5 more
doaj   +1 more source

Granulosa cell tumour: a recurrence 40 years after initial diagnosis. [PDF]

, 2005
peer reviewed[en] BACKGROUND: Granulosa cell tumours are rare ovarian malignancies accounting for 2% to 5% of ovarian tumours. They are characterized by late recurrences, with the latest recurrence reported 37 years after first diagnosis.
Gauthier, Philippe, Alobaid, Abdulaziz, Goffin, Frédéric, East, Nathalie, Ouallouche, Karim   +4 more
core   +1 more source

Luteoma of pregnancy masquerading as a granulosa cell tumor

, 2023
Pregnancy luteomas are rare, nonmalignant lesions thought to be caused by hormonal changes during pregnancy. Granulosa cell tumor is a rare type of ovarian cancer; 10% occur during pregnancy and typically present with elevated inhibin levels.
Cici Liu, Cynthia Angel, Jaclyn Morrison, Eva Pressman, Naixin Zhang, Janira Navarro Sanchez, Sarah Thappa, Richard Moore, Ashlee Smith, Brent DuBeshter   +9 more
core   +1 more source