Results 61 to 70 of about 5,436,969 (234)

Granulosa cell tumor of testis: Clinicopathological correlation of a rare tumor

open access: yesIndian Journal of Pathology and Microbiology, 2014
Background: Granulosa cell tumor of testis is a rare tumor accounting for less than 4% of adult testicular tumors though they account for nearly 30% of childhood testicular tumors.
Swapnil Ulhas Rane   +4 more
doaj   +1 more source

Longitudinal AMH trajectories, ovarian reserve recovery, and fertility outcomes after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia: A real‐world cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize anti‐Müllerian hormone (AMH) recovery after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia (GTN) and evaluate the impact of regimen and hysterectomy. Methods This was a retrospective cohort of 68 high‐risk GTN patients treated with EMA/CO (etoposide, methotrexate, actinomycin D ...
Wei Xue   +8 more
wiley   +1 more source

High-Throughput Analysis of Ovarian Granulosa Cell Transcriptome [PDF]

open access: yesBioMed Research International, 2014
The quality of follicular oocytes depends on interactions with surrounding granulosa cells. Development of molecular techniques and methods enables better understanding of processes underlying mammalian reproduction on cellular level. The success in reproductive biology and medicine in different species depends on reliable assessment of oocyte and ...
openaire   +3 more sources

Intraovarian, Isoform-Specific Transcriptional Roles of Progesterone Receptor in Ovulation

open access: yesCells, 2022
Progesterone receptor (PGR) activity is obligatory for mammalian ovulation; however, there is no established direct functional pathway explaining how progesterone receptor completely and specifically regulates oocyte release.
Kirsten M. Smith   +8 more
doaj   +1 more source

Case series of rare ovarian malignancy: granulosa cell tumor [PDF]

open access: yes, 2017
Granulosa cell tumors are rare ovarian sex cord stromal tumors characterized by indolent course and favorable prognosis. The treatment of granulosa cell tumor is individualized based on many factors like age, desire for future fertility and stage of the ...
Palanivelu Chinnusamy   +7 more
core   +1 more source

Fertility counseling and preservation considerations in patients with gynecologic and non‐gynecologic BRCA and Lynch‐associated malignancies

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Lynch syndrome and BRCA‐mutation associated malignancies are fortunately rare. Affected patients have an increased risk of cancer diagnosis at a young age, often significantly overlapping with their reproductive years. In helping these patients, oncologists must navigate the following areas of care: cancer prevention, impact of cancer ...
Anna Weimer   +20 more
wiley   +1 more source

Conserved SERPINE2 function maintains ovarian estrogen production to support fertility in goats and mice

open access: yesiMetaOmics, EarlyView.
Single‐nucleus RNA sequencing and functional profiling of goat ovaries with divergent litter sizes revealed prolificacy‐associated granulosa cell (GC) states characterized by enhanced proliferation‐ and steroidogenesis‐related features, together with altered predicted cell–cell communication.
Sanbao Zhang   +6 more
wiley   +1 more source

Luteotropic roles of glucocorticoids in rat granulosa cells

open access: yesReproductive and Developmental Medicine, 2020
Objective: The study objective was to investigate whether endogenous glucocorticoids directly impact the functions and proliferation/apoptosis of ovarian granulosa cells.
Xin-Yan Huang   +3 more
doaj   +1 more source

Apoptosis of granulosa cell.

open access: yes, 2018
A. Flow cytometry analysis was performed to measure the apoptotic status of granulosa cell. B. Compared with control group, the apoptotic rate of ovarian granulosa cells in POF, CH +, CH ++ and CH +++ groups was significantly higher ...
YaXin Hu (5586848)   +9 more
core   +1 more source

Lactobacillus johnsonii attenuates ovarian aging by remodeling the gut–ovary axis

open access: yesiMetaOmics, EarlyView.
Aging is accompanied by a reduced abundance of L. johnsonii and ovarian decline. Supplementation with L. johnsonii elevates microbial IPA production via the LdhA enzyme and commensal bacteria. IPA activates the AhR/YAP signaling axis, promoting YAP nuclear translocation and inducing the expression of downstream target genes CYR61 and CTGF. This cascade
Jiamin He   +16 more
wiley   +1 more source

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