Results 131 to 140 of about 61,342 (328)

Ovarian reserve in the dynamics of the girls-teenagers and young women after surgical treatment for benign ovarian disease

open access: yesRUDN Journal of Medicine, 2012
It was done estimation the condition of ovarian reserve of 51 women 15—25 years old in dynamic after surgery and conservative treatment for benign non-inflammatory ovarian diseases, by identification of AMG level, ovarian volume and count of antral ...
T N Zulumyan   +5 more
doaj  

Machine Science in Biomedicine: Practicalities, Pitfalls and Potential

open access: yes, 2010
Machine Science, or Data-driven Research, is a new and interesting scientific methodology that uses advanced computational techniques to identify, retrieve, classify and analyse data in order to generate hypotheses and develop models.
Kelsey, T W, Wallace, W H B
core   +1 more source

Dual Targeting of Mutant p53 and SNRPD2 via Engineered Exosomes Modulates Alternative Splicing to Suppress Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Mutant p53 drives oncogenic splicing to promote the progression of ovarian cancer by partnering with the spliceosome factor SNRPD2. Therefore, it is engineered iRGD‐exosomes to co‐deliver siRNAs against both targets. This approach restored tumor‐suppressive mRNA isoforms, effectively enhanced sensitivity to cisplatin, and ultimately blocked tumor ...
Wei Zhao   +14 more
wiley   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

open access: yesAdvanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou   +9 more
wiley   +1 more source

Investigation of Allium sativum’s Protective Effect on Ovarian Reserve in an Experimental Ovarian Injury Model [PDF]

open access: diamond, 2018
Gürhan Güney   +5 more
openalex   +1 more source

Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone [PDF]

open access: gold, 2023
Ernando Igo Teixeira de Assis   +14 more
openalex   +1 more source

HMGB2–RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat Infiltration

open access: yesAdvanced Science, EarlyView.
This study constructed the first developmental atlas of embryonic skeletal muscle fibro/adipogenic progenitors (FAPs) and identified an HMGB2+ FAPs subpopulation that regulates FAP pool size and muscle homeostasis. HMGB2 directly targets the RAD21 promoter, and its knockout significantly reduces FAP numbers, thereby lowering the potential for ...
Xian Tong   +14 more
wiley   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

open access: yesAdvanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu   +9 more
wiley   +1 more source

Annual fecundity, batch fecundity, and oocyte atresia of Atka mackerel (Pleurogrammus monopterygius) in Alaskan waters [PDF]

open access: yes, 2007
Annual potential fecundity, batch fecundity, and oocyte atresia were estimated for Atka mackerel (Pleurogrammus monopterygius) collected in Alaskan waters during 1993−94.
Gunderson, Donald R.   +2 more
core  

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