Results 141 to 150 of about 400,273 (297)

A Tri‐Culture Heart‐on‐a‐Chip Platform With iPSC‐Derived Cardiac Cells for Predictive Cardiotoxicity Testing

Advanced Healthcare Materials, EarlyView.
This study presents the first entirely isogenic heart‐on‐chip, unifying cardiomyocytes, fibroblasts, and endothelial cells from a single iPSC source. The platform reveals a critical biological insight: the endothelium actively shields cardiac tissue from drug‐induced toxicity, challenging the predictive accuracy of conventional, avascular models for ...
Karine Tadevosyan, Jose Yeste, Mar Alvarez, Denise Marrero, Laura Casado‐Medina, Yvonne Richaud‐Patin, Olalla García‐Iglesias, Jagoda Litowczenko, Alba Morillas Garcia, Anton Guimerà, Xavi Illa, Rosa Villa, Angel Raya   +12 more
wiley   +1 more source

Reducing Long‐Standing Surface Ozone Overestimation in Earth System Modeling by High‐Resolution Simulation and Dry Deposition Improvement

Journal of Advances in Modeling Earth Systems
The overestimation of surface ozone concentration in low‐resolution global atmospheric chemistry and climate models has been a long‐standing issue. We first update the ozone dry deposition scheme in both high‐ (0.25°) and low‐resolution (1°) Community ...
Yang Gao, Wenbin Kou, Wenxuan Cheng, Xiuwen Guo, Binglin Qu, Yubing Wu, Shaoqing Zhang, Hong Liao, Deliang Chen, L. Ruby Leung, Oliver Wild, Junxi Zhang, Guangxing Lin, Hang Su, Yafang Cheng, Ulrich Pöschl, Andrea Pozzer, Leiming Zhang, Jean‐Francois Lamarque, Alex B. Guenther, Guy Brasseur, Zhao Liu, Haitian Lu, Chenlin Li, Bin Zhao, Shuxiao Wang, Xin Huang, Jingshan Pan, Guangliang Liu, Xin Liu, Haipeng Lin, Yuanhong Zhao, Chun Zhao, Junlei Meng, Xiaohong Yao, Huiwang Gao, Lixin Wu   +36 more
doaj   +1 more source

Beyond Presumptions: Toward Mechanistic Clarity in Metal‐Free Carbon Catalysts for Electrochemical H2O2 Production via Data Science

Advanced Materials, EarlyView.
Metal‐free carbon catalysts enable the sustainable synthesis of hydrogen peroxide via two‐electron oxygen reduction; however, active site complexity continues to hinder reliable interpretation. This review critiques correlation‐based approaches and highlights the importance of orthogonal experimental designs, standardized catalyst passports ...
Dayu Zhu, Hsi‐wen Wu, Xiao Wang, Jie Zhang   +3 more
wiley   +1 more source

Regularized Overestimated Newton

We propose Regularized Overestimated Newton (RON), a Newton-type method with low per-iteration cost and strong global and local convergence guarantees for smooth convex optimization. RON interpolates between gradient descent and globally regularized Newton, with behavior determined by the largest Hessian overestimation error.
Duan, Danny, Lyu, Hanbaek
openaire   +2 more sources

Flexoelectrically Induced Polar Topology in Twisted SrTiO3 Membranes

Advanced Materials, EarlyView.
Twisted SrTiO3 bilayers host polar vortices of flexoelectric origin, revealed through combined experiment and theory. By reconstructing polarization from the toroidal moment of strain gradients, the work establishes a 3D chiral state with broken inversion and mirror symmetries.
Isabel Tenreiro, Hugo Aramberri, Víctor Rouco, Gabriel Sánchez‐Santolino, Mariona Cabero, Fernando Gallego, David Sánchez‐Manzano, José M. González‐Calbet, Federico Mompeán, Mar García‐Hernández, Alberto Rivera‐Calzada, Jorge Íñiguez‐González, Carlos León, Jacobo Santamaría   +13 more
wiley   +1 more source

Overestimation of ulcerative colitis due to melanosis coli

Acta Gastroenterológica Latinoamericana, 2010
La melanosis coli es un depósito benigno de pigmento en la mucosa del colon que puede ser vista durante una colonoscopía, especialmente en pacientes con historia de abuso de laxantes.
Jorge A Zapatier, Alison Schneider, Javier L Parra   +2 more
doaj  

Superionic Amorphous Li2ZrCl6 and Li2HfCl6

Advanced Materials, EarlyView.
Amorphous Li2HfCl6 and L2ZrCl6 are shown to be promising solid‐state electrolytes with predicted ionic conductivities >20 mS·cm−1. Molecular dynamics simulations with machine‐learning force fields reveal that anion vibrations and flexible MCl6 octahedra soften the Li coordination cage and enhance mobility. Correlation between Li‐ion diffusivity and the
Shukai Yao, De‐en Jiang
wiley   +1 more source

4D‐Printed Spin Crossover Metamaterials with Giant Programmable Positive or Negative Thermal Expansion

Advanced Materials, EarlyView.
Spin crossover composite filaments are implemented for the rational design of 4D‐printed mechanical metamaterials. The obtained bi‐material structures guided by a theoretical analysis based on analytical calculations and Finite Element Analysis simulations exhibit giant programmable positive or negative deformation with coefficients of thermal ...
Adelais Trapali, Yuteng Zhang, Seyed Ehsan Alavi, Nagham Mawassy, Raja Zulkarnain, Gábor Molnár, Lionel Salmon, Azzedine Bousseksou   +7 more
wiley   +1 more source

Data‐Driven Discovery of Quaternary Ammonium Interlayers for Efficient and Thermally Stable Perovskite Solar Cells

Advanced Materials, EarlyView.
An active learning framework, grounded in independently generated in‐house experimental data, enables reliable discovery of high‐performance interfacial materials for perovskite solar cells. Iterative model refinement autonomously converges toward structurally robust quaternary ammonium architectures, establishing a new design principle for interfacial
Jongbeom Kim, Yang Jeong Park, Chaehoon Jeon, Nahye Shin, Jaewang Park, Seungun Lee, Jino Im, Sungroh Yoon, Sang Il Seok   +8 more
wiley   +1 more source

Short‐Wavelength Infrared Imaging with Organic Photodetectors Based on Non‐Fullerene Acceptors with Detection above 1200 nm

Advanced Materials, EarlyView.
Solution‐processed organic photodetectors (OPDs) based on two novel low band gap non‐fullerene acceptors BZIC‐2F and BZIC‐2Cl, when blended with common polymer donor P3HT, extend detection range beyond 1200 nm with superior performance, rivaling costly inorganic sensors and past literature.
Zhuoran Qiao, Sandeep Sharma, Yakun He, Marie Houot, Kun‐Han Lin, Davide Nodari, Filip Aniés, Matilde Brunetta, Patipan Sukpoonprom, Eunyoung Hong, Edoardo Angela, Zian Wang, Pichaya Pattanasattayavong, Martyn A. McLachlan, Artem Bakulin, Denis Andrienko, Frédéric Laquai, Martin Heeney, Nicola Gasparini   +18 more
wiley   +1 more source