Results 151 to 160 of about 155,664 (264)

Agent‐Based Simulations of Lung Tumor Evolution Suggest That Ongoing Cell Competition Drives Realistic Clonal Expansions

open access: yesAdvanced Science, EarlyView.
Computational simulations of tumor evolution are increasingly used to infer the rules underlying cancer growth, with the goal of one day recommending tailored treatments. Here we show that the properties of lung cancer sequencing data are best replicated by a model which assumes that cells compete both to proliferate and survive. ABSTRACT Computational
Helena Coggan   +5 more
wiley   +1 more source

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

open access: yesAdvanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao   +6 more
wiley   +1 more source

Unraveling Hierarchical B‐Site Ordering: Mechanism of Microwave Dielectric Enhancement in Complex Perovskite Oxide Ceramics

open access: yesAdvanced Science, EarlyView.
This study maps out the hierarchical ordering in 1:2 B‐site complex perovskite ceramics using a comprehensive multiscale characterization route. It turns out that intradomain strain, oxygen vacancies, and Mg disorder within the ordered domains act as strong phonon scatterers.
Qingqiao Fu   +6 more
wiley   +1 more source

Breaking the Kinetics–Loading Trade‐Off in Zinc‐Ion Hybrid Capacitors Through Synergistic Electron–Ion Transport Design

open access: yesAdvanced Science, EarlyView.
High‐mass‐loading carbon cathodes are essential for practical zinc‐ion hybrid capacitors but suffer from severe transport limitations. By combining low‐tortuosity freeze‐dried pore channels with carbon nanotube conductive networks, simultaneous optimization of ion and electron transport is achieved, enabling high‐rate, long‐life pouch cells and ...
Jiacheng Wu   +8 more
wiley   +1 more source

Lipidomic Profile Reconstruction of Therapeutic Membrane Targets Using Physics‐Based Optimization with Limited Activity Data

open access: yesAdvanced Science, EarlyView.
Using a minimal set of experimentally labeled antimicrobial and non‐antimicrobial peptides, we reconstruct the effective lipid composition of a pathogenic membrane ‐demonstrated at the example of bacterial membranes‐ through a physics‐based evolutionary molecular dynamics (Evo‐MD) approach. Optimization based on peptide insertion reveals broad‐spectrum
Maximilian Krebs, Herre Jelger Risselada
wiley   +1 more source

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