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Cad Overexpression in Mammalian Cells
Clinical Biochemistry, 1997Hamster CAD is a multifunctional protein which catalyzes the first three enzymatic steps of de novo pyrimidine biosynthesis.1'2 The major catalytic domains of CAD are car-bamyl phosphate synthetase (CPSase) (EC 6.3.5.5), dihydroorotase (DHOase) (EC 3.5.2.3), and aspartate transcarbamylase (ATCase) (EC 2.1.3.2). The first enzyme of the pathway, carbamyl
Y, Qiu, J N, Davidson
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Lentiviral Overexpression of miRNAs
2013Deregulation of microRNAs (miRNAs) has been attributed to almost any human disease analyzed to date. This calls for models and experimental strategies for functional analyses of miRNAs enabling miRNA overexpression or suppression in target cell and/or tissues.
Hannah, Zöllner +2 more
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Potassium channel overexpression
2000Ion channels in the plasma membrane play a critical role in cellular function. These proteins are the gatekeepers that control ion homeostasis and shape excitability. Excitable cells use a variety of different ion channels to fashion their hallmark electrical signal, the action potential.
U. C. Hoppe +4 more
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Ep-CAM overexpression in breast cancer as a predictor of survival
Lancet, The, 2000Gilbert Spizzo
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Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
Nature, 2011Filipe Cabreiro +2 more
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