Results 41 to 50 of about 2,719,020 (292)

Current development and technology status of high performance rudders

open access: yesZhongguo Jianchuan Yanjiu, 2020
The rudder performance is closely related to the ship performance,and the application of high performance rudders has important significance on improving maneuverability and rapidity of the ship.
LI Feng   +3 more
doaj   +1 more source

An Overview of the Yeast Biodiversity in the Galapagos Islands and other Ecuadorian Regions. [PDF]

open access: yes, 2014
One of the most emblematic natural regions for studies of evolution and biodiversity in the world is the Galápagos Islands, which is the inspiring environment where the naturalist Charles Darwin was moved to propose what eventually became Theory of the ...
Carvajal Barriga, Enrique Javier
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Overview of Meta-Analyses of Five Non-pharmacological Interventions for Alzheimer's Disease

open access: yesFrontiers in Aging Neuroscience, 2020
Background: Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive memory deficits, cognitive decline, and spatial disorientation. Non-pharmacological interventions to treat AD have been reported in many meta-analyses (MAs),
Liao-Yao Wang   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

TECHNOLOGY FORESIGHT OF PATENT MANAGEMENT: AN OVERVIEW ON BIG DATA FOR REPOSITORY FIELDS

open access: yesJurnal Bisnis dan Manajemen, 2019
The development of technology for entering the revolution industries 4.0 era nowadays becomes a hot issue in all industries. This condition is more interesting to discover in reducing budget expenditure, especially in the production process and obtaining
Tommy Hendrix
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Nástupnictví rodinných firem v České republice – přehledový článek [PDF]

open access: yesTrendy v podnikání, 2017
Family business has always played an important role in any economy. As family businesses develop and grow, a question of sustainability arises. To maintain family businesses in the long term it is necessary for them to be passed on to future generations.
Ondřej Hradský
doaj  

Emergencies Overview

open access: yes, 2010
During an animal disease emergency, surveillance measures will be an essential component of the response activities. This Just-In-Time presentation will overview the importance and role of surveillance activities during an animal disease emergency ...
Surveillance Overview
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

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