Results 91 to 100 of about 161,650 (261)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Acupuncture for treatment of insomnia: An overview of systematic reviews

Complementary Therapies in Medicine, 2019
To evaluate the reliability of the methodological quality and outcome measures of systematic review (SR) /meta-analysis (MA) of acupuncture for insomnia.We conducted a comprehensive literature search for SRs with MAs in seven international and Chinese databases.
Wenbo, He, Meixuan, Li, Liqian, Zuo, Meng, Wang, Lili, Jiang, Houqian, Shan, Xue, Han, Kehu, Yang, Xuemei, Han   +8 more
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Psychological distress and self-psychological adjustment methods of lung transplant recipients: an overview of systematic reviews

BMC Psychology
Background Lung transplant recipients (LTRs) face unique psychological distress post-transplantation, which may potentially impact their recovery, so establishing effective psychological coping mechanisms can significantly impact their recovery and ...
Shaobo Guo, Yingtian Jia, Ruiting Wang, Jing Sun, Hongxia Liu   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Acupressure: An Overview of Systematic Reviews [PDF]

Journal of Pain and Symptom Management, 2010
Edzard, Ernst, Myeong Soo, Lee
openaire   +2 more sources

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

A brief overview of systematic reviews and meta-analyses

Indian Journal of Anaesthesia, 2016
Systematic reviews (SRs) are performed to acquire all evidence to address a specific clinical question and involve a reproducible and thorough search of the literature and critical appraisal of eligible studies. When combined with a meta-analysis (quantitatively pooling of results of individual studies), a rigorously conducted SR provides the best ...
Kamath Sriganesh, Harsha Shanthanna, Jason W Busse   +2 more
openaire   +3 more sources

Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review [version 2; peer review: 2 approved]

F1000Research
Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however ...
Marie Williams, Naomi Clifford, Farhad Shokraneh, Naomi Thorpe, Avril Drummond, Jo Leonardi-Bee, Terry Quinn, Eirini Kontou, Roshan das Nair, Sandra Wydera   +9 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source