Results 71 to 80 of about 161,650 (261)

Clinical and pharmacokinetic/dynamic outcomes of prolonged infusions of beta-lactam antimicrobials: An overview of systematic reviews.

PLoS ONE, 2021
ObjectiveThis overview of reviews aims to map and compare of objectives, methods, and findings of existing systematic reviews to develop a greater understanding of the information available about prolonged beta-lactam infusions in hospitalized patients ...
Pierre Thabet, Anchal Joshi, Erika MacDonald, Brian Hutton, Wei Cheng, Adrienne Stevens, Salmaan Kanji   +6 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Overview of Telerehabilitation Methods – Systematic Review

Rehabilitacja Medyczna
Introduction: Along with the rapid advancement of digital technology, the demand for its application in rehabilitation is growing. Innovative healthcare support solutions, for instance, telerehabilitation and remote monitoring, are beginning to play an increasingly important role. Telerehabilitation – defined as a branch of telecommunications utilising
Magdalena Zalewska, Tomasz Wloch, Adrianna Tarnówka, Roman Nowobilski   +3 more
openaire   +3 more sources

Telenursing as an Effective Ally for Improving Patient Outcomes in Diabetes? An Umbrella Review

Nursing Open
Aim To evaluate telenursing interventions' effectiveness in managing patients with diabetes mellitus. Design Overview of systematic reviews. Review Methods According to the PRISMA statement, we included studies published from 2005 to 2023 that evaluated ...
Marika Lo Monaco, Arianna Profeta, Salvatore Corrao   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Acupuncture for rheumatic conditions: an overview of systematic reviews [PDF]

Rheumatology, 2010
Several systematic reviews (SRs) have assessed the effectiveness of acupuncture for rheumatic conditions, often with contradictory conclusions. Our aim is to provide a critical evaluation and summary of these data.Electronic searches were conducted in 15 databases to locate all SRs on acupuncture for rheumatic conditions published since 2000. Data were
Edzard, Ernst, Myeong Soo, Lee
openaire   +2 more sources

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

Molecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic, Maria Concetta Vitale, Rita Siino, Emilia Di Giovanni, Carla Ferrante Bannera, Enrico Di Marco, Andrea Gottardo, Tancredi Didier Bazan Russo, Nadia Barraco, Alessandro Perez, Valerio Gristina, Antonio Galvano, Giuseppe Badalamenti, Antonio Russo, Viviana Bazan, Lorena Incorvaia   +15 more
wiley   +1 more source

CrossFit Overview: Systematic Review and Meta-analysis [PDF]

Sports Medicine - Open, 2018
CrossFit is recognized as one of the fastest growing high-intensity functional training modes in the world. However, scientific data regarding the practice of CrossFit is sparse. Therefore, the objective of this study is to analyze the findings of scientific literature related to CrossFit via systematic review and meta-analysis.Systematic searches of ...
Claudino, Joao Gustavo, Gabbett, Tim J., Bourgeois, Frank, de Sa Souza, Helton, Miranda, Rafael Chagas, Mezencio, Bruno, Soncin, Rafael, Cardoso Filho, Carlos Alberto, Bottaro, Martim, Hernandez, Arnoldo Jose, Amadio, Alberto Carlos, Serrao, Julio Cerca   +11 more
openaire   +4 more sources

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

The use of eHealth with immunizations: An overview of systematic reviews

Vaccine, 2018
eHealth interventions may help increase vaccination uptake and health literacy related to immunization and improve immunization program efficiency.To see where and how eHealth technologies have had a positive impact on immunization practices-using eHealth strategies to increase vaccination uptake, improve immunization program efficiency and advance ...
Elsy Maria, Dumit, David, Novillo-Ortiz, Marcela, Contreras, Martha, Velandia, M Carolina, Danovaro-Holliday   +4 more
openaire   +2 more sources