Results 91 to 100 of about 259,578 (273)

Effects of Ox-LDL on Macrophages NAD(P)H Autofluorescence Changes by Two-photon Microscopy [PDF]

, 2006
Ox-LDL uptakes by macrophage play a critical role in the happening of atherosclerosis. Because of its low damage on observed cells and better signal-to- background ratio, two-photon excitation fluorescence microscopy is used to observe NAD(P)H ...
Dong, Chen-Yuan, Lee, Szu-Yuan, Lin, Chii-Wann, Lin, Ching-Ting, Lu, Long-Sheng, Tien, En-Kuang, Wu, Chau-Chung   +6 more
core   +1 more source

Potential cardiovascular risk protection of bilirubin in end-stage renal disease patients under hemodialysis [PDF]

, 2014
We evaluated the potential cardiovascular risk protection of bilirubin in hemodialysis (HD) patients. An enlarged set of studies were evaluated in 191 HD patients, including hematological study, lipid profile, iron metabolism, nutritional, inflammatory ...
Belo, L., Bronze-da-Rocha, E., Costa, E., Kohlova, M., Miranda, V., Nascimento, H., Quintanilha, A., Reis, F., Ribeiro, S., Rocha-Pereira, P., Sameiro-Faria, M., Santos-Silva, A., Teixeira, L.   +12 more
core   +4 more sources

Compartmentalisation in cAMP signalling: A phase separation perspective

British Journal of Pharmacology, EarlyView.
Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley   +1 more source

Oxidised LDL Cholesterol (Ox-LDL-C) and Ox-LDL-C/HDL Cholesterol (HDL-C) Ratio in Acute Coronary Syndrome Patients versus Chronic Coronary Artery Disease Patients on Statin Treatment [PDF]

Journal of Clinical and Diagnostic Research, 2019
Introduction: Oxidised Low Density Lipoprotein Cholesterol (Ox-LDL-C) and High Density Lipoprotein Cholesterol (HDL-C) have antagonistic action in the development of atherosclerotic cardiovascular disease.
Sumina Cheriyan, Deepti Girija Nandakumaran, D Dinesh Roy, Jaideep Mahendra, Viji Krishnan   +4 more
doaj   +1 more source

Dietary cholesterol withdrawal reduces vascular inflammation and induces coronary plaque stabilization in miniature pigs [PDF]

, 2017
Objective: To study the effect of dietary cholesterol withdrawal on size and composition of LDL-hypercholesterolemia-induced coronary plaques in miniature pigs.
Bernar, Hilde, Dymarkowski, Steven, Gabbiani, Giulio, Hao, Hiroyuki, Holvoet, Paul, Janssens, Stefan, Knaapen, Michiel, Kockx, Mark, Quarck, Rozenn, Van Cleemput, Johan, Verhamme, Peter, Vermylen, Jozef   +11 more
core  

H19 knockdown suppresses proliferation and induces apoptosis by regulating miR-148b/WNT/β-catenin in ox-LDL -stimulated vascular smooth muscle cells

Journal of Biomedical Sciences, 2018
Long non-coding RNAs (lncRNAs) have been identified as critical regulators in the development of atherosclerosis (AS). Here, we focused on discussing roles and molecular mechanisms of lncRNA H19 in vascular smooth muscle cells (VSMCs) progression.
Lei Zhang, Hailing Cheng, Yuxia Yue, Shuangzhan Li, Daping Zhang, Ruili He   +5 more
semanticscholar   +1 more source

Notoginsenoside R1 upregulates miR-221-3p expression to alleviate ox-LDL-induced apoptosis, inflammation, and oxidative stress by inhibiting the TLR4/NF-κB pathway in HUVECs

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2020
Atherosclerosis (AS) is a common vascular disease, which can cause apoptosis of vascular endothelial cells. Notoginsenoside R1 (NGR1) is considered an anti-AS drug.
Lingbo Zhu, Xinyan Gong, J. Gong, Y. Xuan, Ting Fu, Shimao Ni, Lei Xu, Ningning Ji   +7 more
semanticscholar   +1 more source

Endocrine and androgenic response to altitude training in professional cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss, Bastien Krumm, Claes Cubel, Magnus Bak Klaris, Lasse Vestli Baekken, Yvette Dehnes, Jenna Goodrum, Geoff Miller, James Spragg, Martin Faulhaber, Francesco Botrè, Carsten Lundby   +11 more
wiley   +1 more source

Anti-ox-LDL antibodies and anti-ox-LDL-B2GPI antibodies in patients with systemic lupus erythematosus.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2013
The aim of the study was to assess the concentration of anti-oxidized low-density lipoprotein (anti-oxLDL) antibodies and antibodies against oxLDL-beta2GPI (oxLDL-beta 2 glycoprotein I) complexes in the serum of patients with systemic lupus erythematosus (SLE).
Beata, Nowak, Magdalena, Szmyrka-Kaczmarek, Anna, Durazińska, Rafał, Płaksej, Krzysztof, Borysewicz, Lucyna, Korman, Piotr, Wiland   +6 more
openaire   +1 more source

Short-Chain Fatty Acids Weaken Ox-LDL-Induced Cell Inflammatory Injury by Inhibiting the NLRP3/Caspase-1 Pathway and Affecting Cellular Metabolism in THP-1 Cells

Molecules, 2022
Short-chain fatty acids (SCFAs) are important anti-inflammatory metabolites of intestinal flora. Oxidized low-density lipoprotein (ox-LDL)-induced macrophage activation is critical for the formation of atherosclerosis plaque.
Chengxue Yi, Wen Sun, Longkun Ding, Man Yan, Chang Sun, Chenguang Qiu, Dongxu Wang, Liang Wu   +7 more
doaj   +1 more source