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Antibacterial and Antiviral Activities of 1,3,4-Oxadiazole Thioether 4H-Chromen-4-one Derivatives.

Journal of Agricultural and Food Chemistry, 2021
Various 1,3,4-oxadiazole thioether 4H-chromen-4-one derivatives were conceived. The title compounds demonstrated striking inhibitory effects against Xac, Psa, and Xoo. EC50 data exhibited that A8 (19.7 μg/mL) had better antibacterial activity against Xoo
Feng Peng   +8 more
semanticscholar   +1 more source

Enhancement of Energetic Performance through the Construction of Trinitromethyl Substituted β-Bis(1,2,4-oxadiazole).

Journal of Physical Chemistry Letters, 2022
Halogen-free substitutions of ammonium perchlorate (AP), which meet the requirements of high density, high performance, and acceptable stability, have been a subject of scientific research for many years.
Jinya Zhang   +5 more
semanticscholar   +1 more source

Synthetic Transformation of 4-fluorobenzoic acid to 4-fluorobenzohydrazide Schiff Bases and 1,3,4-Oxadiazole Analogs having DPPH Radical Scavenging Potential

Letters in Drug Design & Discovery, 2022
Synthesis of 4-fluorobenzohydrazide Schiff bases and 1,3,4-oxadiazole analogs has DPPH radical scavenging potential. Synthetic antioxidants are widely used because they are effective and cheaper than natural antioxidants.
Momin Khan   +6 more
semanticscholar   +1 more source

Review of the biological activities of heterocyclic compounds comprising oxadiazole moieties.

Current Topics in Medicinal Chemistry, 2022
The oxadiazole core is considered as a privileged moiety in many medicinal chemistry applications. The oxadiazole class includes 1,2,3-oxadiazole, 1,2,4-oxadiazole, 1,3,4-oxadiazole and 1,2,5-oxadiazole.
B. Ruan   +5 more
semanticscholar   +1 more source

1,3,4‐oxadiazole derivatives as potential antimicrobial agents

Chemical Biology and Drug Design, 2022
Due to the emergence of drug‐resistant microbial strains, different research groups are continuously developing novel drug molecules against already exploited and unexploited targets.
D. Tiwari   +5 more
semanticscholar   +1 more source

1,3,4‐oxadiazole and its derivatives: A review on recent progress in anticancer activities

Chemical Biology and Drug Design, 2020
The 1,3,4‐oxadiazole nucleus is a biologically imperative scaffold possesses numerous biological activities. The broad and potent activity of 1,3,4‐oxadiazole and their derivatives has established them as important pharmacological scaffolds especially in
Ankur Vaidya, D. Pathak, K. Shah
semanticscholar   +1 more source

A patent review of pharmaceutical and therapeutic applications of oxadiazole derivatives for the treatment of chronic diseases (2013–2021)

Expert Opinion on Therapeutic Patents, 2022
Introduction Oxadiazole is a unique class of heterocycle, possessing numerous important biomedical and therapeutic applications, such as anti-bacterial, anti-cancer, anti-inflammatory, inhibitors for diverse enzymes, receptor modulators, and ...
Abbas Hassan   +4 more
semanticscholar   +1 more source

Iridium Supported on Porous Polypyridine-Oxadiazole as High Active and Recyclable Catalyst for Borrowing Hydrogen Reaction

Green Chemistry, 2022
Homogenization of heterogeneous catalysts is a valuable and interesting research topic. Porous polypyridine-oxadiazole (PPO), which was not only a carrier but also a ligand, was designed and synthesized from pyridine-oxadiazole...
Jiahao Li   +4 more
semanticscholar   +1 more source

Perfluoro-1,3,4-oxadiazoles

Journal of Fluorine Chemistry, 1992
Abstract Some new polyfluorinated 1,3,4-oxadiazoles have been obtained via a two-step method. The cycloadditions of the 1,3,4-oxadiazoles have been studied and an analysis of the energies of the frontier orbitals calculated by the MNDO method indicates a LUMO-dependent pathway for cycloaddition.
N.V. Vasiliev   +3 more
openaire   +1 more source

Banana-Shaped 1,2,4-Oxadiazole Analogues of 1,3,4-Oxadiazoles

Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals, 2001
Abstract In the last years bent banana-shaped mesomorphic molecules found an increasingly great interest among theoreticians and experimentalists due to the nature of this type of liquid crystals to exhibit a spontaneous polarization in the absence of any chiral group in the molecules.
S. I. TORGOVA   +3 more
openaire   +2 more sources

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