Results 251 to 260 of about 40,843 (302)

1,3,4‐oxadiazole derivatives as potential antimicrobial agents

Chemical Biology and Drug Design, 2022
Due to the emergence of drug‐resistant microbial strains, different research groups are continuously developing novel drug molecules against already exploited and unexploited targets.
D. Tiwari, R. Narang, Kalvatala Sudhakar, Vikramjeet Singh, S. Lal, M. Devgun   +5 more
semanticscholar   +1 more source

A patent review of pharmaceutical and therapeutic applications of oxadiazole derivatives for the treatment of chronic diseases (2013–2021)

Expert Opinion on Therapeutic Patents, 2022
Introduction Oxadiazole is a unique class of heterocycle, possessing numerous important biomedical and therapeutic applications, such as anti-bacterial, anti-cancer, anti-inflammatory, inhibitors for diverse enzymes, receptor modulators, and ...
Abbas Hassan, Abid Hussain Khan, F. Saleem, H. Ahmad, K. Khan   +4 more
semanticscholar   +1 more source

Iridium Supported on Porous Polypyridine-Oxadiazole as High Active and Recyclable Catalyst for Borrowing Hydrogen Reaction

Green Chemistry, 2022
Homogenization of heterogeneous catalysts is a valuable and interesting research topic. Porous polypyridine-oxadiazole (PPO), which was not only a carrier but also a ligand, was designed and synthesized from pyridine-oxadiazole...
Jiahao Li, Anruo Mao, Wei Yao, Haiyan Zhu, Dawei Wang   +4 more
semanticscholar   +1 more source

Antibacterial and Antiviral Activities of 1,3,4-Oxadiazole Thioether 4H-Chromen-4-one Derivatives.

Journal of Agricultural and Food Chemistry, 2021
Various 1,3,4-oxadiazole thioether 4H-chromen-4-one derivatives were conceived. The title compounds demonstrated striking inhibitory effects against Xac, Psa, and Xoo. EC50 data exhibited that A8 (19.7 μg/mL) had better antibacterial activity against Xoo
Feng Peng, Tin-yin Liu, Qifan Wang, Fang Liu, Xiao Cao, Jinsong Yang, Li-wei Liu, C. Xie, Wei Xue   +8 more
semanticscholar   +1 more source

Oxadiazoles in Medicinal Chemistry

Journal of Medicinal Chemistry, 2012
Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms. Oxadiazoles are frequently occurring motifs in druglike molecules, and they are often used with the intention of being bioisosteric replacements for ester and amide functionalities.
Alleyn T. Plowright, Jonas Boström, Eric Wellner, Anders Hogner, Antonio Llinas   +4 more
openaire   +2 more sources

Banana-Shaped 1,2,4-Oxadiazole Analogues of 1,3,4-Oxadiazoles

Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals, 2001
Abstract In the last years bent banana-shaped mesomorphic molecules found an increasingly great interest among theoreticians and experimentalists due to the nature of this type of liquid crystals to exhibit a spontaneous polarization in the absence of any chiral group in the molecules.
S. I. TORGOVA, L. A. KARAMYSHEVA, T. A. GEIVANDOVA, STRIGAZZI, Alfredo   +3 more
openaire   +3 more sources

1,3,4‐oxadiazole and its derivatives: A review on recent progress in anticancer activities

Chemical Biology and Drug Design, 2020
The 1,3,4‐oxadiazole nucleus is a biologically imperative scaffold possesses numerous biological activities. The broad and potent activity of 1,3,4‐oxadiazole and their derivatives has established them as important pharmacological scaffolds especially in
Ankur Vaidya, D. Pathak, K. Shah
semanticscholar   +1 more source

ChemInform Abstract: Perfluoro‐1,3,4‐oxadiazoles.

ChemInform, 1992
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
N. V. Vasiliev, A. E. Patalakha, G. A. Sokolski, Yu. E. Lyashenko   +3 more
openaire   +3 more sources

1,2,4‐Oxadiazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

1,3,4-Oxadiazole Containing Compounds As Therapeutic Targets For Cancer Therapy.

Mini-Reviews in Medical Chemistry, 2021
BACKGROUND Cancer is the first or second leading cause of premature death in 134 of 183 countries in the world. 1,3,4-Oxadiazoles are five memebered heterocyclic rings containing two nitrogen (two atoms) and oxygen (one atom).
M. Ahsan
semanticscholar   +1 more source