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Current Advancement in the Oxadiazole-Based Scaffolds as Anticancer Agents

Polycyclic aromatic compounds (Print), 2021
Heterocyclic nucleus is vital in medicinal chemistry and has allured significant attention in chemotherapeutic domain. Oxadiazole, a five-membered nitrogen–oxygen-containing heterocyclic core has remarkable anticancer activity.
Garima Kapoor   +7 more
semanticscholar   +1 more source

1,2,5-Oxadiazoles

ChemInform, 1996
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Oxadiazole-Triphenylamine derivatives for OLEDs

SPIE Proceedings, 2005
Electroluminescent bipolar small molecules have been attracted with great interests recently. They are found to exhibit many interesting features such as (i) reducing the structural complexity of organic light emitting diodes (OLEDs) from multilayer heterojunction to monolayer homojunction devices; (ii) offering molecular p/n junction, and (iii ...
Louis M L Leung   +8 more
openaire   +3 more sources

1,3,4-Oxadiazole Bridges: A Strategy to Improve Energetics at the Molecular Level.

Angewandte Chemie, 2020
Many energetic materials synthesized to date have limited applications because of low thermal and/or mechanical stability. This limitation can be overcome by introducing structural modifications such as a bridging group.
Jinchao Ma   +5 more
semanticscholar   +1 more source

Synthesis, In vitro α-Glucosidase Inhibitory Potential and Molecular Docking Studies of 2-Amino-1,3,4-Oxadiazole Derivatives.

Medicinal chemistry, 2020
BACKGROUND In the recent past, we had synthesized and reported different derivatives of oxadiazoles as potential α-glucosidase inhibitors. Keeping in mind, the pharmacological aspects of oxadiazole moiety and in continuation of our ongoing research on ...
H. Ullah   +8 more
semanticscholar   +1 more source

Infrared spectra of 1,3,4-oxadiazole and 2,5,-dimethyl-1,3,4-oxadiazole. Vibrational assignment of 1,3,4-oxadiazole

Journal of Molecular Spectroscopy, 1967
Abstract The infrared absorption spectrum of 1,3,4-oxadiazole has been recorded in the region 5000-400 cm −1 in the vapor and in the liquid phases, in CS 2 and C 2 Cl 4 solutions. Also, the infrared absorption spectrum of liquid 2,5-dimethyl-1,3,4-oxadiazole was recorded in the same region. A tentative assignment of the fundamental vibrations of 1,
Jørgen Tormod Nielsen   +2 more
openaire   +2 more sources

Poly‐1,3,4‐oxadiazoles. I. Polyphenylene‐1,3,4‐oxadiazoles

Journal of Polymer Science Part A: General Papers, 1965
AbstractPolyphenylene‐1,3,4‐oxadiazoles have been prepared from benzenedicarboxylic acids or their derivatives and hydrazine by solution polycondensation in fuming sulfuric acid or polyphosphoric acid. These polymers were characterized by good thermal stability, and the molecular weights attained were high enough for the products to exhibit fiber‐or ...
Shigeyoshi Hara   +2 more
openaire   +2 more sources

Oxadiazole grafts in peptide macrocycles

Nature Chemistry, 2016
Synthetic methods that provide control over macrocycle conformation and, at the same time, mitigate the polarity of peptide bonds represent valuable tools for the discovery of new bioactive molecules. Here, we report a macrocyclization reaction between a linear peptide, an aldehyde and (N-isocyanimino)triphenylphosphorane.
Conor C. G. Scully   +2 more
openaire   +3 more sources

The new era of 1,2,4-oxadiazoles

Organic & Biomolecular Chemistry, 2009
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
PACE, Andrea, PIERRO, Paola
openaire   +5 more sources

SACCHARIDE 1,3,4-OXADIAZOLES

Organic Preparations and Procedures International, 1976
AbstractBei einer Behandlung mit Jod und HgO werden die Acylhydrazone (I) zu den entsprechenden Saccharid‐oxadiazolen (III) cyclisiert.
M. Nassr, M. Shaban
openaire   +2 more sources

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