Results 11 to 20 of about 5,507 (218)
International Journal of Molecular Sciences, 2022 Oxadiazoles are electron-poor, five-membered aromatic heterocycles that contain one oxygen and two nitrogen atoms [...
Antonio Palumbo Piccionello
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ChemInform, 2008 The uses of 1,2,4-oxadiazoles include those as agonists at muscarinic receptors, 5-hydroxytryptamine (5-HT) receptor antagonists, benzodiazepine receptor agonists, potent antagonists of the (serotonin) 5-HT1B/D receptors, muscarinic receptor ...
K. Hemming, Hemming, Karl, Hemming, K.
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Banana-shaped 1,2,4 oxadiazoles
Pramana, 2003 3,5-Disubstituted 1,2,4-oxadiazoles are a new type of liquid crystalline (LC) compounds with asymmetrical five-membered heterocycle as a central unit. They have a bent shape and are very convenient model-compounds for studying the dependence of the LC ...
Geivandova, T.A. +8 more
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Synthesis and Pharmacological Characterization of Metronidazole-Oxadiazole Derivatives [PDF]
Iranian Journal of Medical Sciences, 2023 Background: The use of antibiotics with or without prescription is increasing worldwide. With certain limitations, metronidazole (MTZ) is extensively used as an antibacterial and antiparasitic drug.
Mohsin Mohammed, Nadia Haj
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The oxadiazole antibacterials [PDF]
Current Opinion in Microbiology, 2016 The oxadiazoles are a class of antibacterials discovered by in silico docking and scoring of compounds against the X-ray structure of a penicillin-binding protein. These antibacterials exhibit activity against Gram-positive bacteria, including against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE).
Jeshina, Janardhanan +2 more
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Synthesis and characterization of new phthalimides and succinimides substituted with 1,3,4-oxadiazole ring [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 A series of new phthalimides and succinimides connected to 1,3,4-oxadiazole moiety were synthesized via multistep synthesis. The first step involved synthesis of six 5- substituted 2- amino-1,3,4-oxadiazoles by oxidative cyclization of substituted ...
Ahlam Marouf Al-Azzawi +1 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 Heterocyclic compounds make a very important branch of organic chemistry, and it has always been an interesting area of study in medical chemistry. They are present in a variety of drugs, vitamins and biologically active compounds. Over two decades, 1,
Yu. V. Karpenko +2 more
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The new era of 1,2,4-oxadiazoles
Organic & Biomolecular Chemistry, 2009 The synthesis, the chemical and photochemical reactivity, and the use of 1,2,4-oxadiazoles in materials and as bioactive compounds have been reviewed.
PIERRO, Paola, PACE, Andrea
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Bioactive Oxadiazoles 3.0. [PDF]
Int J Mol SciHeterocycles are fundamental moieties for the construction of new compounds with perspective applications ranging from drugs to materials [...]
Palumbo Piccionello A.
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Molecules, 2021 A series of deoxycholic acid (DCA) amides containing benzyl ether groups on the steroid core were tested against the tyrosyl-DNA phosphodiesterase 1 (TDP1) and 2 (TDP2) enzymes.
Oksana V. Salomatina +9 more
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