Results 11 to 20 of about 5,960 (212)
A new and efficient synthesis of substituted 2-amino-1,3,4-oxadiazoles from isothiocyanates and hydrazides [PDF]
BMC Chemistry1,3,4-Oxadiazoles are privileged heterocyclic scaffolds with broad bioactivities, holding significant importance in pharmaceutical and agrochemical discovery.
Lei Wu +6 more
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Synthesis of 2,5-Dialkyl-1,3,4-oxadiazoles Bearing Carboxymethylamino Groups
Molecules, 2022 A series of new symmetrical 2,5-dialkyl-1,3,4-oxadiazoles containing substituted alkyl groups at the terminal positions with substituents, such as bromine, isopropyloxycarbonylmethylamino, and carboxymethylamino, were successfully synthesized.
Marcin Łuczyński +2 more
doaj +2 more sources
International Journal of Molecular Sciences, 2022 Oxadiazoles are electron-poor, five-membered aromatic heterocycles that contain one oxygen and two nitrogen atoms [...]
Antonio Palumbo Piccionello
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Synthesis and Antimicrobial Evaluation of Some New Oxadiazoles Derived from Phenylpropionohydrazides
Molecules, 2009 In this study a series ofnew1-(2-aryl-5-phenethyl-1,3,4-oxadiazol-3(2H)-yl)ethanones 2a-e was synthesized by the cyclization of imines 1a-e using acetic anhydride. The products were evaluated for anti-bacterial and anti-fungal activity.
Gunjan Singh +2 more
exaly +3 more sources
Functionalized Nitrile Oxides and Their Synthetic Equivalents: Recent Advances in Generation Methods and Synthetic Applications [PDF]
MoleculesFunctionalized nitrile oxides have attracted increasing attention because the incorporated functional groups not only influence cycloaddition reactivity but also provide valuable handles for subsequent molecular diversification.
Nagatoshi Nishiwaki
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Bioactive Oxadiazoles 3.0. [PDF]
Int J Mol SciHeterocycles are fundamental moieties for the construction of new compounds with perspective applications ranging from drugs to materials [...]
Palumbo Piccionello A.
europepmc +4 more sources
Bioscience Journal, 2022 In recent years, investigations in the field of oxadiazoles have been intensified due to their numerous therapeutic uses. Oxadiazoles are a class of compounds that exhibit several biological applications, citing antimicrobial, anti-inflammatory, anti ...
Josefa Aqueline da Cunha Lima +6 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2021 Acetylene derivatives of 1,2,4-oxadiazoles, i.e., 5-(2-arylethynyl)-3-aryl-1,2,4-oxadiazoles, have been obtained, for the first time reported, from 5-(2-arylethenyl)-3-aryl-1,2,4-oxadiazoles by their bromination at the carbon–carbon double bond followed ...
Andrey I. Puzanov +6 more
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021 Heterocyclic compounds make a very important branch of organic chemistry, and it has always been an interesting area of study in medical chemistry. They are present in a variety of drugs, vitamins and biologically active compounds. Over two decades, 1,
Yu. V. Karpenko +2 more
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Synthesis and Pharmacological Characterization of Metronidazole-Oxadiazole Derivatives [PDF]
Iranian Journal of Medical Sciences, 2023 Background: The use of antibiotics with or without prescription is increasing worldwide. With certain limitations, metronidazole (MTZ) is extensively used as an antibacterial and antiparasitic drug.
Mohsin Mohammed, Nadia Haj
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