Results 31 to 40 of about 5,507 (218)
BIOLOGICALLY ACTIVE OXADIAZOLE
Journal of Drug Delivery and Therapeutics, 2015 As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are three known isomers that is 1,2,4-oxadiazole, 1,2,3-oxadiazole and 1,2,5-oxadiazole (Figure 1.0 ...
Chhama Shukla, Sanchit Srivastav
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Molecules, 2022 The bioisosteres of 1,3,4-oxadiazoles and 1,3,4-thiadiazoles are well-known pharmacophores for many medicinally important drugs. Throughout the past 10 years, 1,3,4-oxa-/thiadiazole nuclei have been very attractive to researchers for drug design ...
Rana M. El-Masry +3 more
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Molecules, 2021 A series of N-pyridyl ureas bearing 1,2,4- (1a, 2a, and 3a) and 1,3,4-oxadiazole moiety (1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as well as X-ray diffraction.
Sergey V. Baykov +6 more
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Oxadiazoles in Medicinal Chemistry
, 2016 Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms.
Eric Wellner (1589959) +4 more
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2-(4-Bromophenoxy)propanohydrazide
Acta Crystallographica Section E, 2009 The title compound, C9H11BrN2O2, is an important intermediate for the synthesis of heterocyclic compounds such as azoles, 2,5-disubstituted-1,3,4-oxadiazoles and 5-substituted 2-mercapto-1,3,4-oxadiazoles. The bromophenoxy group subtends a dihedral angle
Shahid Hameed +3 more
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Synthesis of Some Substituted 1,3,4-Oxadiazoles from Hydrazones [PDF]
مجلة التربية والعلم, 2009 In this paper the synthesis of some 2-(3-pyridyl)-5-aryl-1,3,4-oxadiazoles from hydrazones is reported. Nicotinic acid was converted to ethyl nicotinate (1) by its reaction with thionyl chloride and the resultant acid chloride was treated with absolute ...
Khalid Daoud, A. Ahmad, Amal Ali
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Quantum chemical research of the molecular structure of 3,4-dicyanofuroxan
Тонкие химические технологии, 2023 Objectives. The study set out to determine the equilibrium parameters of the 3,4-dicyanofuroxan molecule by means of molecule geometry optimization by quantum chemistry methods, verify the adequacy of the methods used, and compare the obtained results ...
I. N. Kolesnikova +3 more
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Expanding Synthesizable Space of Disubstituted 1,2,4-Oxadiazoles
, 2017 One-pot synthesis of 3,5-disubstituted 1,2,4-oxadiazoles from carboxylic acids and nitriles was optimized to parallel chemistry. The method was validated on a 141 member library; the desired products were recovered with a high success rate and in ...
Andrey Tolmachev (1514266) +10 more
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Editorial for Special Issue “Bioactive Oxadiazoles”
, 2021 Oxadiazoles are electron-poor, five-membered aromatic heterocycles containing one oxygen and two nitrogen atoms [...
Antonio Palumbo Piccionello
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, 2016 The scope of intramolecular Diels−Alder and a novel tandem Diels−Alder/1,3-dipolar cycloaddition cascade of 1,3,4-oxadiazoles is disclosed. In the cases examined, the tandem cycloadditions construct three new rings with formation of four new C−C bonds ...
Dale L. Boger (1306542) +7 more
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