Results 31 to 40 of about 5,960 (212)
Molecules, 2021 A series of N-pyridyl ureas bearing 1,2,4- (1a, 2a, and 3a) and 1,3,4-oxadiazole moiety (1b, 2b, 3b) was prepared and characterized by HRMS, 1H and 13C NMR spectroscopy, as well as X-ray diffraction.
Sergey V. Baykov +6 more
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Synthesis of Some Substituted 1,3,4-Oxadiazoles from Hydrazones [PDF]
مجلة التربية والعلم, 2009 In this paper the synthesis of some 2-(3-pyridyl)-5-aryl-1,3,4-oxadiazoles from hydrazones is reported. Nicotinic acid was converted to ethyl nicotinate (1) by its reaction with thionyl chloride and the resultant acid chloride was treated with absolute ...
Khalid Daoud, A. Ahmad, Amal Ali
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Quantum chemical research of the molecular structure of 3,4-dicyanofuroxan
Тонкие химические технологии, 2023 Objectives. The study set out to determine the equilibrium parameters of the 3,4-dicyanofuroxan molecule by means of molecule geometry optimization by quantum chemistry methods, verify the adequacy of the methods used, and compare the obtained results ...
I. N. Kolesnikova +3 more
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Synthesis and Antineoplastic Evaluation of Novel Unsymmetrical 1,3,4-Oxadiazoles
, 2016 A series of novel 1,3,4-oxadiazoles was synthesized and evaluated for their cytotoxic activity in in vitro tumor models. Four of the new compounds (2d, 2j, 2k, and 2n) showed growth inhibition in the XTT dye assay.
Giansalvo Pinna (3367052) +7 more
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Editorial for Special Issue “Bioactive Oxadiazoles”
, 2021 Oxadiazoles are electron-poor, five-membered aromatic heterocycles containing one oxygen and two nitrogen atoms [...
Antonio Palumbo Piccionello
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Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020 At the present stage of development of medical chemistry, many basic synthetic approaches to the synthesis of 1,3,4-oxadiazole structures are known, which are focused mainly on the principles of combinatorial chemistry with a wide range of biological ...
Yu. V. Karpenko +2 more
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Potassium (3-Methyl-2-oxido-1,2,5-oxadiazol-4-yl)dinitromethanide
Molbank, 2021 Furoxan derivatives enriched with explosophoric functionalities are promising compounds in the preparation of novel energetic materials. Herein, a previously unknown potassium (3-methyl-2-oxido-1,2,5-oxadiazol-4-yl)dinitromethanide (also referred to as ...
Egor S. Zhilin +2 more
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Oxidative Cyclization Protocol for the Preparation of Energetic 3‑Amino-5‑R‑1,2,4-oxadiazoles
, 2018 An efficient method has been developed for the synthesis of energetic 3-amino-5-R-1,2,4-oxadiazoles via iodobenzene diacetate (IBD)-mediated oxidative cyclization in high yields at ambient temperature.
Jean’ne M. Shreeve (1267290) +3 more
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2:1 Adducts Arising from Reactions between Benzynes and 1,3,4-Oxadiazoles
2:1 adducts arise from the reaction of 2,5-diaryl-1,3,4-oxadiazoles and benzynes generated from the hexadehydro-Diels–Alder (HDDA) reaction. Density functional theory computations support a mechanistic manifold that includes a concerted SNAr process ...
Paul V. Kevorkian (10522165) +2 more
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Frontiers in Oncology, 2018 Aberrant activation of NF-κB is linked with the progression of human malignancies including hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential target in the treatment of several cancers.
Chakrabhavi Dhananjaya Mohan +13 more
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