Results 51 to 60 of about 6,176 (169)

Synthesis of Some 1,4-Bis (Substituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles) Benzene From Terephthalic Acid [PDF]

open access: yesمجلة التربية والعلم, 1999
In this paper the synthesis of some 1,4-bis-(substituted1,3,4-oxadiazoles and 1,2,4-trizoles) benzene from terephthalic acid is reported. Terephthalic acid was esterified with absolute ethanol in presence of concentrated sulfuric acid to give ethyl ...
K. Daoud, E. Mahmood, M. Salih
doaj   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

open access: yesChemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens   +3 more
wiley   +1 more source

Reaction of 2,5-Disubstituted-1,3,4-oxadiazoles [PDF]

open access: yes, 1985
Some 5-aryl-2-mercapto-1,3,4-oxadiazole (I) reacted with maleic anhydride, maleic acid and p-benzoquinone affording 2-(5-aryl- -1,3,4-oxadiazol-2-ylthio)succinic anhydrides (II), 2-(5-aryl-1,3,4- -oxadiazol-2-ylthio)succinic acids (III) and 2-(2,5 ...
El-Barbary, Ahmed A.
core  

Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency

open access: yesMolecular Therapy: Nucleic Acids
Nonsense mutations are among the genetic causes of LRBA (lipopolysaccharide-responsive beige-like anchor) deficiency, a rare autosomal-recessive immunodeficiency disorder.
Ignazio Fiduccia   +13 more
doaj   +1 more source

Recent advances and prospects for high‐efficiency blue hot exciton organic light‐emitting diodes

open access: yesFlexMat, EarlyView.
Blue organic light‐emitting diodes (OLEDs) face great challenges in achieving the balance between color purity, device efficiency, and stability. Hot exciton materials offer a solution by rapidly converting non‐emissive triplet excitons into singlet ones through a high‐lying reverse intersystem crossing process.
Xiaoen Shi   +3 more
wiley   +1 more source

Oxadiazoles in Medicinal Chemistry

open access: yes, 2016
Oxadiazoles are five-membered heteroaromatic rings containing two carbons, two nitrogens, and one oxygen atom, and they exist in different regioisomeric forms.
Eric Wellner (1589959)   +4 more
core   +2 more sources

PREPARAÇÃO DE 1,2,4-OXADIAZOL: SEQUÊNCIA DIDÁTICA APLICADA EM DISCIPLINA DE SÍNTESE ORGÂNICA NA GRADUAÇÃO

open access: yesQuímica Nova
1,2,4-oxadiazoles are used in a wide range of applications, including medicinal chemistry and chemistry of materials. However, this kind of oxadiazoles is not usually prepared in an undergraduate organic teaching laboratory.
Juliana L. L. Freire Regueira   +2 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Heterocycles from saccharide hydrazones. Part I. Saccharide 1,3,4-oxadiazoles

open access: yes, 1972
Oxidation, with iodine-mercuric oxide, of acetylated saccharide aroylhydrazones and of aromatic aldehyde hydrazones yields 5-aryl-2-(polyacetoxyalkyl)-1,3,4-oxadiazoles and 2,5-diaryl-1,3,4-oxadiazoles, respectively.
H. El Khadem   +5 more
core   +1 more source

Efficient Phosphonium-Mediated Synthesis of 2-Amino-1,3,4-oxadiazoles

open access: yes, 2016
We present an efficient, room temperature procedure for the preparation of 2-amino-1,3,4-oxadiazoles. Oxadiazol-2-ones can be activated for SNAr substitution using phosphonium reagents (e.g., BOP).
Zhao-Kui Wan (2004907)   +1 more
core   +2 more sources

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