Results 51 to 60 of about 5,960 (212)

BIOLOGICALLY ACTIVE OXADIAZOLE

open access: yesJournal of Drug Delivery and Therapeutics, 2015
As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are three known isomers that is 1,2,4-oxadiazole, 1,2,3-oxadiazole and 1,2,5-oxadiazole (Figure 1.0 ...
Chhama Shukla, Sanchit Srivastav
openaire   +2 more sources

Oxaziridines: Versatile Reagents in Modern Organic Synthesis

open access: yesThe Chemical Record, EarlyView.
Being capable of transferring an O atom and N‐group/atom, oxaziridines are considered multitasking agents. These are employed for diverse organic transformations, such as epoxidation of olefins, α‐ and γ‐hydroxylation/amination of carbonyl compounds, oxidation of sulfides, [3+2]cycloaddition with unsaturated systems.
Ajeet Chandra   +2 more
wiley   +1 more source

Beyond the stop: Oxadiazole TRIDs restore LRBA protein expression in nonsense-driven primary immunodeficiency

open access: yesMolecular Therapy: Nucleic Acids
Nonsense mutations are among the genetic causes of LRBA (lipopolysaccharide-responsive beige-like anchor) deficiency, a rare autosomal-recessive immunodeficiency disorder.
Ignazio Fiduccia   +13 more
doaj   +1 more source

Harnessing benzamides as plant stress inhibitors, growth promoters and in management of crop resilience—A review

open access: yesPlant Biology, EarlyView.
Benzamides boost crop resilience by inhibiting poly(ADP‐ribose) polymerase (PARP) to enhance stress tolerance and, through their antimicrobial, herbicidal, and insecticidal derivatives, they offer broad protection for sustainable crop improvement. Abstract Benzamides have emerged as potent stress inhibitors and growth promoters in plant biotechnology ...
M. J. Koetle, T. E. Motaung, S. O. Amoo
wiley   +1 more source

Synthesis and photochemistry of di-substituted-1,2,4-oxadiazoles

open access: yes, 2000
Four di-substituted-1,2,4-oxadiazoles were synthesized. They were tested by NMR, UV spectroscopy, and GC trace. The oxadiazoles were irradiated with 254nm and 300nm light to test their photoreactivity and attempt to prove benzonitrile was a ...
Adams, Alisha Marie
core   +3 more sources

Synthesis and characterization of 1,3,4-oxadiazoles bearing an indole ring [PDF]

open access: yes, 2020
1,3,4-oxadiazoles are important in various fields and have been involved in many studies by researchers. 1,3,4-oxadiazoles have many biological activities, for example, antifungal, antibacterial and anti-oxidant activities.
Ng, Yu Xuan
core   +1 more source

PREPARAÇÃO DE 1,2,4-OXADIAZOL: SEQUÊNCIA DIDÁTICA APLICADA EM DISCIPLINA DE SÍNTESE ORGÂNICA NA GRADUAÇÃO

open access: yesQuímica Nova
1,2,4-oxadiazoles are used in a wide range of applications, including medicinal chemistry and chemistry of materials. However, this kind of oxadiazoles is not usually prepared in an undergraduate organic teaching laboratory.
Juliana L. L. Freire Regueira   +2 more
doaj   +1 more source

Synthesis of Some 1,4-Bis (Substituted 1,3,4-Oxadiazoles and 1,2,4-Triazoles) Benzene From Terephthalic Acid [PDF]

open access: yesمجلة التربية والعلم, 1999
In this paper the synthesis of some 1,4-bis-(substituted1,3,4-oxadiazoles and 1,2,4-trizoles) benzene from terephthalic acid is reported. Terephthalic acid was esterified with absolute ethanol in presence of concentrated sulfuric acid to give ethyl ...
K. Daoud, E. Mahmood, M. Salih
doaj   +1 more source

Oxadiazolone‐Triazole Derivatives as a New Scaffold for Modulation of Angiotensin II‐Induced Vascular Contraction

open access: yesChemMedChem, Volume 21, Issue 17, 14 September 2026.
A novel series of candidate AT1 receptor antagonists based on oxadiazolone‐triazole scaffolds was designed and synthesized. Most compounds reduced angiotensin II‐induced vascular contraction in an initial biological screening, with compound 7f emerging as the most active derivative.
Larissa F. L. Ferreira   +5 more
wiley   +1 more source

Heterocyclic‐Based Fungicides: Emerging Strategies for Viable Plant Disease Control

open access: yesChemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Heterocyclic compounds have attracted considerable attention because of their structural diversity, potent antifungal activity, and ability to interact with multiple fungal targets, offering broad‐spectrum protection against phytopathogens. Synthetic and semisynthetic/part‐natural scaffolds, particularly azole, quinoline, indole, cyclotryptamine, and ...
Sumit Tahlan   +4 more
wiley   +1 more source

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