Results 51 to 60 of about 8,710 (181)
A sustainable rewritable paper platform is developed using biopolymer‐based aqueous colored inks and organic acid–treated substrates. Localized protonation induces in situ fibrous hydrogel network formation that anchors dyes for stable handwriting, painting, and inkjet printing.
Damini Jagankar +2 more
wiley +1 more source
Synthesis of Azoles Condensed with, or Linked to, Nitroxides [PDF]
Nitroxides connected to indoles, tetrazoles, or 1,3,4-oxadiazoles were synthesized by conventional and microwave-assisted cyclization reactions. New approaches to pyrrole-, pyrazole-, and triazoleannulated nitroxides are described.
Bognár, Balázs +4 more
core +1 more source
In Silico, In Vitro, and In Vivo Antinociceptive Potential of S‐Naproxen Derivatives
Selected naproxen derivatives were investigated for their antinociceptive effects, using in vitro (COX‐I/COX‐II antagonistic effect), in vivo (acetic acid and hot plate assay), and in silico (molecular simulation studies) approaches. The COX inhibition studies revealed that the maximum percent effect exhibited by GMO‐I‐111a 96.01 and 92% against COX‐2 ...
Ubaidullah +13 more
wiley +1 more source
An expanding range of targets for kynurenine metabolites of tryptophan [PDF]
The kynurenine pathway of tryptophan metabolism accounts for most of the tryptophan that is not committed to protein synthesis and includes compounds active in the nervous and immune systems.
Darlington, L. Gail +2 more
core +1 more source
Orally active antischistosomal early leads identified from the open access malaria box. [PDF]
BACKGROUND: Worldwide hundreds of millions of schistosomiasis patients rely on treatment with a single drug, praziquantel. Therapeutic limitations and the threat of praziquantel resistance underline the need to discover and develop next generation drugs.
A Fenwick +42 more
core +5 more sources
Bioactive Azoles with Three Heteroatoms [PDF]
This issue is dedicated to scientists belonging to either or both the fields of heterocyclic and medicinal chemistry. Nowadays, pharmaceutical industries are more and more dedicating their research towards different use or applications of the same ...
PACE, A
core
Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
core +1 more source
Cross Linking and Degradation Mechanisms in Model Sealant Candidates [PDF]
Model compounds were investigated as to which type of heterocyclic ring is the most advantageous for curing sealants based on perfluoroalkylether chains. The relative thermal, thermal oxidative, hydrolytic, and fuel stability of potential crosslinks were
Ito, T. I. +4 more
core +1 more source
QSAR-Driven Discovery of Novel Chemical Scaffolds Active against Schistosoma mansoni. [PDF]
Schistosomiasis is a neglected tropical disease that affects millions of people worldwide. Thioredoxin glutathione reductase of Schistosoma mansoni (SmTGR) is a validated drug target that plays a crucial role in the redox homeostasis of the parasite.
Anne E. Carpenter +16 more
core +3 more sources
Chemical research projects office: An overview and bibliography, 1975-1980 [PDF]
The activities of the Chemical Research Projects Office at Ames Research Center, Moffett Field, California are reported. The office conducts basic and applied research in the fields of polymer chemistry, computational chemistry, polymer physics, and ...
Heimbuch, A. H. +2 more
core +1 more source

