Results 21 to 30 of about 3,169 (181)

SYNTHESIS OF SOME 1,3,4- OXADIAZOLES FROM ETHYL IMIDAZO [4,5-B] PYRIDINYL PROPIONATE AS PONTENTIAL ANTIINFLAMMATORY AGENTS

open access: yesZagazig Journal of Pharmaceutical Sciences, 1993
Synthesis of 2- (6-bromo -2- imidazo [4,5-b] pyridinyl) ethyl -5-( substituted) thío 1,3,4 Oxadiazole derivatives is described. The preparation of 1,3,4 - Oxadiazoles was achieved by cyclization of the corresponding acid hydrazide.
Mohamed Ebeid   +4 more
doaj   +1 more source

Quantum chemical research of the molecular structure of 3,4-dicyanofuroxan

open access: yesТонкие химические технологии, 2023
Objectives. The study set out to determine the equilibrium parameters of the 3,4-dicyanofuroxan molecule by means of molecule geometry optimization by quantum chemistry methods, verify the adequacy of the methods used, and compare the obtained results ...
I. N. Kolesnikova   +3 more
doaj   +1 more source

Synthesis of Some Substituted 1,3,4-Oxadiazoles from Hydrazones [PDF]

open access: yesمجلة التربية والعلم, 2009
In this paper the synthesis of some 2-(3-pyridyl)-5-aryl-1,3,4-oxadiazoles from hydrazones is reported. Nicotinic acid was converted to ethyl nicotinate (1) by its reaction with thionyl chloride and the resultant acid chloride was treated with absolute ...
Khalid Daoud, A. Ahmad, Amal Ali
doaj   +1 more source

Potassium (3-Methyl-2-oxido-1,2,5-oxadiazol-4-yl)dinitromethanide

open access: yesMolbank, 2021
Furoxan derivatives enriched with explosophoric functionalities are promising compounds in the preparation of novel energetic materials. Herein, a previously unknown potassium (3-methyl-2-oxido-1,2,5-oxadiazol-4-yl)dinitromethanide (also referred to as ...
Egor S. Zhilin   +2 more
doaj   +1 more source

DFT Study of Regio- and Stereoselective 13DC Reaction between Diazopropane and Substituted Chalcone Derivatives: Molecular Docking of Novel Pyrazole Derivatives as Anti-Alzheimer’s Agents

open access: yesMolecules, 2023
In the present work, a combination of experimental and density functional theory (DFT) investigation of the (3+2) cycloaddition reactions of diazopropane with chalcone derivatives was reported. All calculations were performed using several DFT approaches
Sadeq M. Al-Hazmy   +5 more
doaj   +1 more source

Biologically oriented synthesis of medicines (BIODS) based on heterylpoxid 2,5- disubstituted 1,3,4-oxadiazoles (Part 1)

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2020
At the present stage of development of medical chemistry, many basic synthetic approaches to the synthesis of 1,3,4-oxadiazole structures are known, which are focused mainly on the principles of combinatorial chemistry with a wide range of biological ...
Yu. V. Karpenko   +2 more
doaj   +1 more source

BIOLOGICALLY ACTIVE OXADIAZOLE

open access: yesJournal of Drug Delivery and Therapeutics, 2015
As we know that, Oxadiazole is a heterocyclic compound containing an oxygen atom and two nitrogen atoms in a five-membered ring and is derived from furan by substitution of two methylene groups (=CH) with two pyridine type nitrogen (-N=) [1,2]. There are three known isomers that is 1,2,4-oxadiazole, 1,2,3-oxadiazole and 1,2,5-oxadiazole (Figure 1.0 ...
Chhama Shukla, Sanchit Srivastav
openaire   +2 more sources

Bioactive Oxadiazoles 2.0

open access: yesInternational Journal of Molecular Sciences, 2022
Oxadiazoles are electron-poor, five-membered aromatic heterocycles that contain one oxygen and two nitrogen atoms [...]
openaire   +2 more sources

Recent advances and prospects for high‐efficiency blue hot exciton organic light‐emitting diodes

open access: yesFlexMat, EarlyView.
Blue organic light‐emitting diodes (OLEDs) face great challenges in achieving the balance between color purity, device efficiency, and stability. Hot exciton materials offer a solution by rapidly converting non‐emissive triplet excitons into singlet ones through a high‐lying reverse intersystem crossing process.
Xiaoen Shi   +3 more
wiley   +1 more source

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells

open access: yesFrontiers in Oncology, 2018
Aberrant activation of NF-κB is linked with the progression of human malignancies including hepatocellular carcinoma (HCC), and blockade of NF-κB signaling could be a potential target in the treatment of several cancers.
Chakrabhavi Dhananjaya Mohan   +13 more
doaj   +1 more source

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