Survey on the clinical trial results achieved in Brazil comparing praziquantel and oxamniquine in the treatment of mansoni schistosomiasis [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 1985 A random, double-blind, parallel group clinical trial program was carried out to compare praziquantel, a recently developed anti-helmintic drug, and oxamniquine, an already established agent for treating mansoni schistosomiasis.
Getúlio Leonel de Rezende
doaj +6 more sources
Hipertensão pulmonar esquistossomotica persistente em paciente após reversão da forma hépato-esplênica: apresentação de um caso [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 1986 Os autores relatam o caso de um paciente masculino, de 24 anos, hépato-esplênico e com hipertensão pulmonar esquistossomótica (pressão média na artéria pulmonar de 27,5mm HG). Tratado com oxamniquine.
Antônio Emanuel +3 more
doaj +6 more sources
Resistance of schistosomes to hycanthone and oxamniquine [PDF]
Memorias do Instituto Oswaldo Cruz, 1989 Genetic crosses between phenotypically resistant and sensitive schistosomes demonstrated that resistance to hycanthone and oxamniquine behaves like a recessive trait, thus suggesting that resistance is due to the lack of some factor. We hypothesized that,
Donato Cioli +2 more
doaj +4 more sources
Development and validation of a luminescence-based, medium-throughput assay for drug screening in Schistosoma mansoni [PDF]
, 2015 Schistosomiasis, one of the world's greatest neglected tropical diseases, is responsible for over 280,000 human deaths per annum. Praziquantel, developed in the 1970s, has high efficacy, excellent tolerability, few and transient side effects, simple ...
Altamura, Sergio +5 more
core +13 more sources
Baixa eficácia da associação oxamniquine e praziquantel na cura da esquistossomose mansônica
Revista da Sociedade Brasileira de Medicina Tropical, 1986 Em uma área endêmica onde havia interrupção da transmissão, foram tratados 164 esquistossomóticos com a associação oxamniquine e praziquantel em doses reduzidas.
R. Dietze, A. Prata
doaj +3 more sources
Comparação entre praziquantel e oxamniquine no tratamento da esquistossomose mansoni
Revista da Sociedade Brasileira de Medicina Tropical, 1983 Tratamos 120 pacientes masculinos com idade de 17 a 19 anos, portadores de esquistossomose mansoni nas formas intestinal e hepatointestinal, pareados de acordo com o número de ovos por grama de fezes.
Antônio Emanuel, Aluízio Prata
doaj +3 more sources
Variation in response of Schistosoma mansoni strains to schistosomicides
Revista do Instituto de Medicina Tropical de São Paulo, 1988 The BH strain of Schistosoma mansoni was found to be highly susceptible, to hy cant hone (1 x 80 mg/kg), oxamniquine (1 x 100 mg/kg) niridazole (5 x 100 mg/kg), praziquantel (1 x 100 mg/kg), oltipraz (5 x 125 mg/kg) and amoscanate (1 x 300 mg/kg) and is ...
Luiz Cândido de Souza Dias +2 more
doaj +1 more source
Praziquantel: its use in control of schistosomiasis in sub-Saharan Africa and current research needs [PDF]
, 2009 Treatment with praziquantel (PZQ) has become virtually the sole basis of schistosomiasis control in sub-Saharan Africa and elsewhere, and the drug is reviewed here in the context of the increasing rate that it is being used for this purpose. Attention is
A. MBAYE +22 more
core +2 more sources
Antiplasmodial activity of p-substituted benzyl thiazinoquinone derivatives and their potential against parasitic infections [PDF]
, 2020 Malaria is a life-threatening disease and, what is more, the resistance to available antimalarial drugs is a recurring problem. The resistance of Plasmodium falciparum malaria parasites to previous generations of medicines has undermined malaria control ...
Basilico, Nicoletta +6 more
core +2 more sources
Similar cellular responses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection. [PDF]
, 2009 The effect of treatment with either oxamniquine or praziquantel on S.mansoni specific IFN-gamma, IL-4, IL-5 and IL-10 was compared on PBMC which were collected pretreatment, 6 and 18 weeks post treatment.
Kaluka, Daniel +5 more
core +3 more sources