Persistent Vulvar Itch Unresponsive to Treatment: A Case of Vulvar Schistosomiasis Caused by Schistosoma mansoni and a Brief Review of Literature. [PDF]
Case Rep Infect Dis, 2023 Background. Vulvar schistosomiasis is a female genital schistosomiasis (FGS), which occurs because of the damage caused by the presence of schistosome ova within the vulva. FGS is mostly misdiagnosed as a sexually transmitted infection. There is no reported case of vulvar schistosomiasis from Schistosoma mansoni in an immunocompetent or ...
Gyening-Yeboah A, Quayson SE.
europepmc +2 more sources
Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment [PDF]
bioRxiv, 2019 Do mutations required for adaptation occur de novo, or are they segregating within populations as standing genetic variation? This question is key to understanding adaptive change in nature, and has important practical consequences for the evolution of ...
Frédéric D. Chevalier +22 more
semanticscholar +4 more sources
Survey on the clinical trial results achieved in Brazil comparing praziquantel and oxamniquine in the treatment of mansoni schistosomiasis [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 1985 A random, double-blind, parallel group clinical trial program was carried out to compare praziquantel, a recently developed anti-helmintic drug, and oxamniquine, an already established agent for treating mansoni schistosomiasis.
Getúlio Leonel de Rezende
doaj +6 more sources
Similar cellular responses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection. [PDF]
Malawi medical journal : the journal of Medical Association of Malawi, 2010 The effect of treatment with either oxamniquine or praziquantel on S.mansoni specific IFN-gamma, IL-4, IL-5 and IL-10 was compared on PBMC which were collected pretreatment, 6 and 18 weeks post treatment.
T. Mduluza +5 more
semanticscholar +4 more sources
Resistance of schistosomes to hycanthone and oxamniquine [PDF]
Memorias do Instituto Oswaldo Cruz, 1989 Genetic crosses between phenotypically resistant and sensitive schistosomes demonstrated that resistance to hycanthone and oxamniquine behaves like a recessive trait, thus suggesting that resistance is due to the lack of some factor. We hypothesized that,
Donato Cioli +2 more
doaj +5 more sources
Avaliação terapêutica duplo-cega baseada na técnica do oograma quantitativo, comparando praziquantel com oxamniquine na esquistossomose mansônica humana [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 1986 Um total de 54 pacientes adultos, com esquistossomose mansônica crônica, nas formas intestinal ou hepatintestinal, participou de um ensaio clínico duplo-cego, para comparar o praziquantel com a oxamniquine.
Aloisio Sales da Cunha +1 more
doaj +6 more sources
Stability of Schistosoma mansoni progeny to antischistosomal drugs [PDF]
Revista do Instituto de Medicina Tropical de São Paulo, 1985 The susceptibility of the MAP Brazilian strain (F1 to F5 progenies) of S. mansoni to four antischistosomal drugs has been reported in a previous study. In the present investigation, progeny F14 of the same strain, was tested for stability to the same 4 ...
Luiz Candido de Souza Dias +1 more
doaj +5 more sources
Addressing the oxamniquine in vitro-in vivo paradox to facilitate a new generation of anti-schistosome treatments [PDF]
Int J Parasitol Drugs Drug Resist, 2023 K. Toth +5 more
semanticscholar +2 more sources
PLOS Neglected Tropical Diseases, 2015 Background For over two decades, a racemic mixture of oxamniquine (OXA) was administered to patients infected by Schistosoma mansoni, but whether one or both enantiomers exert antischistosomal activity was unknown. Recently, a ~30 kDa S.
Alexander B Taylor +12 more
semanticscholar +8 more sources
Hipertensão pulmonar esquistossomotica persistente em paciente após reversão da forma hépato-esplênica: apresentação de um caso [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 1986 Os autores relatam o caso de um paciente masculino, de 24 anos, hépato-esplênico e com hipertensão pulmonar esquistossomótica (pressão média na artéria pulmonar de 27,5mm HG). Tratado com oxamniquine.
Antônio Emanuel +3 more
doaj +6 more sources